Search Results - "Kieltyka, Jacqueline"
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JAK Inhibition Differentially Affects NK Cell and ILC1 Homeostasis
Published in Frontiers in immunology (19-12-2019)“…Janus kinase (JAK) inhibitors are widely used in the treatment of multiple autoimmune and inflammatory diseases. Immunologic and transcriptomic profiling have…”
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A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2021)“…The discovery of cytokines and their role in immune and inflammatory disease led to the development of a plethora of targeted biologic therapies. Later,…”
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A Decade of Jakinibs: what have we learned and what may be the future
Published in Arthritis & rheumatology (Hoboken, N.J.) (02-11-2021)“…The discovery of cytokines and their role in immune and inflammatory disease led to the development a plethora of targeted biologic therapies. Later, efforts…”
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Overexpression of Insulin‐like Growth Factor Binding Protein 1 (IGFBP1) Generates Tamoxifen Resistance in Breast Cancer Cells
Published in The FASEB journal (01-04-2018)“…Tamoxifen, a selective estrogen receptor modulator and antagonist for estrogen receptor alpha (ERα) in breast tissue, is a commonly prescribed adjuvant…”
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High throughput pSTAT signaling profiling by fluorescent cell barcoding and computational analysis
Published in Journal of immunological methods (01-02-2020)“…Fluorescent cell barcoding (FCB) is a multiplexing technique for high-throughput flow cytometry (FCM). Although powerful in minimizing staining variability, it…”
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