Search Results - "Kiel, Jeffrey W."
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Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits
Published in Journal of ocular pharmacology and therapeutics (01-04-2015)“…AR-13324 is a potential new drug for the treatment of patients with glaucoma that has been shown to lower intraocular pressure (IOP) by increasing trabecular…”
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2
Effects of chronic mild hyperoxia on retinal and choroidal blood flow and retinal function in the DBA/2J mouse model of glaucoma
Published in PloS one (25-03-2022)“…To test the hypothesis that mild chronic hyperoxia treatment would improve retinal function despite a progressive decline in ocular blood flow in the DBA/2J…”
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3
Potency and Sterility of Fortified Tobramycin, Fortified Vancomycin, and Moxifloxacin at 4, 24, and 35°C for 14 Days
Published in Cornea (01-01-2016)“…PURPOSE:To assess the potency and sterility of ophthalmic antibiotic drops commonly used in the treatment of bacterial keratitis. METHODS:This was a basic…”
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4
Topical Proparacaine and Episcleral Venous Pressure in the Rabbit
Published in Investigative ophthalmology & visual science (01-06-2009)“…To determine the effect of proparacaine-induced topical anesthesia on episcleral venous pressure (EVP). In anesthetized rabbits (n = 11), EVP was measured with…”
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5
Episcleral venous pressure response to brain stem stimulation: Effect of topical lidocaine
Published in Experimental eye research (01-11-2021)“…Episcleral venous pressure (EVP) is important for steady state intraocular pressure (IOP), as it has to be overcome by aqueous humor in order to leave the eye…”
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6
Retinal Vascular and Anatomical Features in the Spontaneously Hypertensive Rat
Published in Current eye research (01-11-2020)“…Purpose: To evaluate whether in vivo optical imaging methods and histology can detect comparable vascular and neuronal damage in the retina due to the effects…”
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7
Effects of Dorzolamide on Retinal and Choroidal Blood Flow in the DBA/2J Mouse Model of Glaucoma
Published in Investigative ophthalmology & visual science (01-03-2016)“…To test the hypothesis that acute topical dorzolamide (DZ) decreases intraocular pressure (IOP) and increases retinal and choroidal blood flow in the DBA/2J…”
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8
Episcleral venous pressure and IOP responses to central electrical stimulation in the rat
Published in Investigative ophthalmology & visual science (21-10-2013)“…Histological evidence suggests a role for the central nervous system in controlling episcleral venous pressure (EVP). Based on prior studies that identified…”
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9
Comparative Pharmacokinetics and Injection Site Histopathology in Nude Mice Treated with Long-acting Buprenorphine Formulations
Published in Journal of the American Association for Laboratory Animal Science (01-03-2023)“…Two long-acting formulations of buprenorphine are commercially available as analgesics for rodents. However, these drugs have not yet been studied in nude…”
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10
Magnetic resonance imaging indicates decreased choroidal and retinal blood flow in the DBA/2J mouse model of glaucoma
Published in Investigative ophthalmology & visual science (01-02-2012)“…This study tests the hypothesis that reduced retinal and choroidal blood flow (BF) occur in the DBA/2J mouse model of glaucoma. Quantitative BF magnetic…”
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11
Effects of Dorzolamide on Choroidal Blood Flow, Ciliary Blood Flow, and Aqueous Production in Rabbits
Published in Investigative ophthalmology & visual science (01-05-2009)“…To determine the effects of topical dorzolamide (a carbonic anhydrase inhibitor) on choroidal and ciliary blood flow and the relationship between ciliary blood…”
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12
Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester
Published in Investigative ophthalmology & visual science (01-03-2010)“…To determine the episcleral venous pressure (EVP) responses to nitroprusside (NP) and L-NAME. In anesthetized rabbits (n = 36), arterial pressure and IOP were…”
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13
Magnetic resonance imaging of vascular oxygenation changes during hyperoxia and carbogen challenges in the human retina
Published in Investigative ophthalmology & visual science (01-01-2011)“…To demonstrate blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) of vascular oxygenation changes in normal, unanesthetized human…”
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14
Choroidal Blood Flow Decreases with Age: An MRI Study
Published in Current eye research (01-10-2014)“…Abstract Purpose: To verify that a visual fixation protocol with cued eye blinks achieves sufficient stability for magnetic resonance imaging (MRI) blood-flow…”
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15
The effect of vasopressin on ciliary blood flow and aqueous flow
Published in Investigative ophthalmology & visual science (21-01-2014)“…Previous experiments have shown that arginine-vasopressin (AVP) reduces intraocular pressure (IOP) dose-dependently. The present study investigated the…”
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16
In vivo depth-resolved oxygen saturation by Dual-Wavelength Photothermal (DWP) OCT
Published in Optics express (21-11-2011)“…Microvasculature hemoglobin oxygen saturation (SaO2) is important in the progression of various pathologies. Non-invasive depth-resolved measurement of SaO2…”
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17
Lamina-specific functional MRI of retinal and choroidal responses to visual stimuli
Published in Investigative ophthalmology & visual science (15-07-2011)“…To demonstrate lamina-specific functional magnetic resonance imaging (MRI) of retinal and choroidal responses to visual stimulation of graded luminance,…”
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18
Pharmacological MRI of the choroid and retina: Blood flow and BOLD responses during nitroprusside infusion
Published in Magnetic resonance in medicine (01-10-2012)“…Nitroprusside, a vasodilatory nitric oxide donor, is clinically used during vascular surgery and to lower blood pressure in acute hypertension. This article…”
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The effect of vasopressin on choroidal blood flow, intraocular pressure, and orbital venous pressure in rabbits
Published in Investigative ophthalmology & visual science (01-09-2011)“…To investigate the effects of arginine-vasopressin (AVP) on intraocular pressure (IOP), orbital venous pressure (OVP), and choroidal blood flow (ChorBF)…”
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20
Postocclusive reactive hyperemia occurs in the rat retinal circulation but not in the choroid
Published in Investigative ophthalmology & visual science (30-07-2013)“…We tested the hypothesis that retinal blood flow has a postocclusive reactive hyperemia response modulated by occlusion duration and metabolic activity, and…”
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