Search Results - "Kiehl, Douglas E"
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The role of mass spectrometry and related techniques in the analysis of extractable and leachable chemicals
Published in Mass spectrometry reviews (01-03-2020)“…In addition to degradation products, impurities, and exogenous contaminants, industries such as pharmaceutical, food, and others must concern themselves with…”
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Facile synthesis of tilmicosin and tylosin related haptens for use as protein conjugates
Published in Journal of antibiotics (01-05-2003)“…Synthesis is described for the haptens 23-demycinosyl-23-deoxy-23-(3-aminoprop-1-yl)-aminotilmicosin (6) from 5-O-mycaminosyltylonolide (OMT) and for…”
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Genetic engineering of aminodeoxyhexose biosynthesis in Streptomyces fradiae
Published in Nature biotechnology (01-07-2002)“…The antibacterial properties of macrolide antibiotics (such as erythromycin, tylosin, and narbomycin) depend ultimately on the glycosylation of otherwise…”
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Identification and Synthesis of an Oxidation Product of Tilmicosin
Published in Journal of agricultural and food chemistry (17-08-1998)“…During formulation development of the veterinary macrolide antibiotic tilmicosin, an oxidation product of the parent molecule was identified. Use of liquid…”
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Electrospray ionization mass spectrometry with in-source collision-induced dissociation of monensin factors and related metabolites
Published in Rapid communications in mass spectrometry (31-07-1998)“…Monensins are a series of polyether ionophore antibiotic factors produced by Streptomyces cinnamonensis. Three monensin factors and four metabolites of…”
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Separation and characterization of the tryptic peptide mapping of recombinant bovine growth hormone by reversed-phase high-performance liquid chromatography electrospray mass spectrometry
Published in Rapid communications in mass spectrometry (01-01-1997)“…Reversed phase high‐performance liquid chromatography (RPHPLC) coupled with electrospray ionization mass spectrometry (ESI‐MS) was used to separate and…”
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Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry
Published in Rapid communications in mass spectrometry (1995)“…Tilmicosin is a semisynthetic macrolide antibiotic used in the treatment of respiratory disease in cattle and swine. The technique of liquid…”
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Improved potency assay for recombinant bovine somatotropin by high-performance size-exclusion chromatography
Published in Journal of Chromatography A (07-06-1996)“…A high-performance size-exclusion chromatographic method was developed for the determination of potency of recombinant bovine somatotropin (rbST) monomer and…”
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