Search Results - "Kieffer, Lynda"

Identification of a Candidate Regulatory Region in the Human CD8 Gene Complex by Colocalization of DNase I Hypersensitive Sites and Matrix Attachment Regions Which Bind SATB1 and GATA-3 by Kieffer, Lynda J, Greally, John M, Landres, Inna, Nag, Shanta, Nakajima, Yuko, Kohwi-Shigematsu, Terumi, Kavathas, Paula B

“…To locate elements regulating the human CD8 gene complex, we mapped nuclear matrix attachment regions (MARs) and DNase I hypersensitive (HS) sites over a…”
Get full text

Human CD8α expression in NK cells but not cytotoxic T cells of transgenic mice by Kieffer, Lynda J., Bennett, Jane A., Cunningham, Ann C., Gladue, Ron P., McNeish, John, Kavathas, Paula B., Hanke, Jeffrey H.

“…In our previous work, DNase hypersensitivity mapping was used to identify an enhancer within the human CD8α (hCD8α) gene which allowed T cell-specific…”
Get full text

Human CD8β, But Not Mouse CD8β, Can Be Expressed in the Absence of CD8α as a ββ Homodimer by Devine, Lesley, Kieffer, Lynda J., Aitken, Victoria, Kavathas, Paula B.

“…Abstract The T cell coreceptor CD8 exists on mature T cells as disulfide-linked homodimers of CD8α polypeptide chains and heterodimers of CD8α- and…”
Get full text

Cyclophilin-40, a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterization by KIEFFER, L. J, SENG, T. W, WEI LI, OSTERMAN, D. G, HANDSCHUMACHER, R. E, BAYNEY, R. M

“…We have reported previously the isolation and preliminary characterization of a 40-kDa cyclosporin A (CsA)-binding protein, cyclophilin-40 (CyP-40). To…”
Get full text

Isolation and characterization of a 40-kDa cyclophilin-related protein by KIEFFER, L. J, THALHAMMER, T, HANDSCHUMACHER, R. E

“…Major and minor isoforms of cyclophilin (CyP-18), a 17.8-kDa protein with peptidyl-prolyl cis-trans isomerase activity, comprise the primary intracellular…”
Get full text

Appropriate developmental expression of human CD8 beta in transgenic mice by Kieffer, LJ, Yan, L, Hanke, JH, Kavathas, PB

“…The human CD8 glycoprotein is expressed either as an alpha beta heterodimer or as an alpha alpha homodimer on thymocytes, mature T cells, and subpopulations of…”
Get full text

A modified cell surface marker gene for transgenic animal studies by Kieffer, Lynda, Kavathas, Paula B.

“…We developed a marker gene encoding a human cell surface molecule called CD8 for use in transgenic animal studies. The CD8 cDNA contains three mutations: one…”
Get full text

Human (CD8 alpha) expression in NK cells but not cytotoxic T cells of transgenic mice by Kieffer, Lynda J, Bennett, Jane A, Cunningham, Ann C, Gladue, Ron P

Get full text

Isolation and characterization of cyclophilin-40 and cloning of itscDNA by Kieffer, Lynda Jane

“…Cyclophilin-18 (CyP-18), a 17.8kD protein with peptidyl-prolyl cis-trans isomerase (PPI-ase) activity, is the primary binding protein for the…”
Get full text

Human CD8{beta}, But Not Mouse CD8{beta}, Can Be Expressed in the Absence of CD8{alpha} as a {beta}{beta} Homodimer by Devine, Lesley, Kieffer, Lynda J, Aitken, Victoria, Kavathas, Paula B

Get full text

Conformational requirements of substrates for activity with phenylethanolamine N-methyltransferase by Grunewald, Gary L, Ye, Qizhuang, Kieffer, Lynda, Monn, James A

“…beta-Phenylethanolamines have long been known to be substrates for the enzyme that converts norepinephrine to epinephrine (phenylethanolamine…”
Get full text

Estradiol decreases retention of rhodamine 123 fluorescence in GH4C1 pituitary tumor cells by Van Itallie, C M, Kieffer, L J, Carbone, R, Dannies, P S

“…Rhodamine 123 is a lipophilic cationic fluorescent dye that localizes in mitochondria. We found that 17 beta-estradiol changes the ability of GH4C1 cells,…”
Get more information

Isolation and partial characterization of membrane‐associated cyclophilin and a related 22‐kDa glycoprotein by THALHAMMER, Theresia, KIEFFER, Lynda J., JIANG, Tian‐rong, HANDSCHUMACHER, Robert E.

“…The presence of membrane‐associated proteins which stereospecifically bind cyclosporin A and react with anti‐cyclophilin antibodies has been documented in rat…”
Get full text