Search Results - "Kiefer, Lea"
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Anti‐KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria
Published in Allergy (Copenhagen) (01-05-2023)“…Background Chronic inducible urticaria (CIndU) is characterized by mast cell (MC)‐mediated wheals in response to triggers: cold in cold urticaria (ColdU) and…”
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Using Wearable Sensors to Measure Goal Achievement in Older Veterans with Dementia
Published in Sensors (Basel, Switzerland) (01-12-2022)“…Aligning treatment with patients' self-determined goals and health priorities is challenging in dementia care. Wearable-based remote health monitoring may…”
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Guiding Post-Hospital Recovery by 'What Matters:' Implementation of Patient Priorities Identification in a VA Community Living Center
Published in Geriatrics (Basel) (04-07-2023)“…Patient priorities care (PPC) is an effective age-friendly health systems (AFHS) approach to aligning care with goals derived from 'what matters'. The purpose…”
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Models for treating depression in specialty medical settings: a narrative review
Published in General hospital psychiatry (01-07-2015)“…Abstract Objective This review answered two questions: (a) what types of specialty medical settings are implementing models for treating depression, and (b) do…”
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Evidence for histamine release in chronic inducible urticaria – A systematic review
Published in Frontiers in immunology (28-07-2022)“…Background Chronic inducible urticaria (CIndU) constitutes a group of nine different CIndUs in which pruritic wheals and/or angioedema occur after exposure to…”
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Empowering patients in chronic care to improve diabetes distress and glycaemic control: Protocol for a hybrid implementation‐effectiveness clinical trial
Published in Endocrinology, diabetes & metabolism (01-01-2020)“…Objectives To evaluate the effectiveness of a collaborative goal‐setting intervention (Empowering Patients in Chronic Care [EPIC]) to improve glycaemic control…”
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TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding
Published in Nature methods (01-03-2018)“…TimeLapse-seq chemically recodes labeled s 4 U nucleosides to a cytidine derivative and monitors transcriptional dynamics. RNA sequencing (RNA-seq) offers a…”
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Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6‑Thioguanosine
Published in Journal of the American Chemical Society (07-11-2018)“…RNA-sequencing (RNA-seq) measures RNA abundance in a biological sample but does not provide temporal information about the sequenced RNAs. Metabolic labeling…”
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A marine pebbly mudstone from the Swiss Alps: palaeotectonic implications and some consequences for the interpretation of Precambrian diamictites
Published in Swiss Journal of geosciences (01-10-2017)“…Pebbly mudstones are a conspicuous element of sedimentary sequences deposited in different tectonic settings and sedimentary environments. Whereas for many…”
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Stella’s Role in Oocyte DNA Methylation Suggests Additional Activities of DNMT1
Published in Biochemistry (Easton) (09-04-2019)Get full text
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Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin
Published in Nature structural & molecular biology (01-03-2020)“…Understanding the targeting and spreading patterns of long non-coding RNAs (lncRNAs) on chromatin requires a technique that can detect both high-intensity…”
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An algorithm for the diagnosis and treatment of chronic inducible urticaria, 2024 update
Published in Allergy (Copenhagen) (01-09-2024)Get full text
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Studying Stimulus‐Induced Changes in RNA Dynamics by Mutational Mapping through TimeLapse‐seq
Published in The FASEB journal (01-04-2018)“…The eukaryotic transcriptome is dynamically regulated through RNA transcription and decay allowing cells to respond to environmental stimuli in a rapid and…”
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New insights into chronic inducible urticaria
Published in Current allergy and asthma reports (01-08-2024)“…Purpose of Review Chronic inducible urticaria (CIndU) is a group of long-persisting and challenging to manage diseases, characterized by recurrent wheals and…”
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Author Correction: Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin
Published in Nature structural & molecular biology (01-04-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Tuning cohesin trajectories enables differential readout of the Pcdhα cluster across neurons
Published in Science (American Association for the Advancement of Science) (26-07-2024)“…Expression of Protocadherin (Pcdh) genes is critical to the generation of neuron identity and wiring of the nervous system. Pcdhα genes are arranged in…”
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Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies
Published in Molecular cell (17-03-2022)“…Splicing factor mutations are common among cancers, recently emerging as drivers of myeloid malignancies. U2AF1 carries hotspot mutations in its RNA-binding…”
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Implementation of patient priorities-aligned care in a home-based primary care program
Published in Journal of the American Pharmacists Association (01-01-2024)“…Older adults may be limited in their ability to access care that meets their health goals owing to disease burden, financial instability, and psychosocial…”
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WAPL functions as a rheostat of Protocadherin isoform diversity that controls neural wiring
Published in Science (American Association for the Advancement of Science) (23-06-2023)“…Neural type-specific expression of clustered Protocadherin (Pcdh) proteins is essential for the establishment of connectivity patterns during brain…”
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Investigation of the Interaction and Role of CHP1 and CHP2 with NHE1 in Lung Fibroblasts
Published in The FASEB journal (01-04-2015)“…Abstract only Intracellular pH (pH i ) homeostasis is crucial for cell survival. The membrane protein Sodium‐Hydrogen exchanger 1 (NHE1) is one of the major…”
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