Search Results - "Kiefel, Ben R"
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Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma
Published in Clinical & translational immunology (2021)“…Objectives The increasing success of Chimeric Antigen Receptor (CAR) T cell therapy in haematological malignancies is reinvigorating its application in many…”
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Bacterial cytoplasmic display platform Retained Display (ReD) identifies stable human germline antibody frameworks
Published in Biotechnology journal (01-05-2015)“…Conventional antibody surface display requires fusion protein export through at least one cellular membrane, constraining the yield and occasioning…”
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Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV
Published in Human vaccines & immunotherapeutics (02-11-2017)“…While broadly neutralizing antibodies (bnAbs) are a promising preventative and therapeutic tool for HIV infection, production is difficult and expensive…”
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Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs
Published in Nature (London) (18-11-2021)“…The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented…”
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Targeting of intracellular oncoproteins with peptide-centric CARs
Published in Nature (London) (23-11-2023)“…The majority of oncogenic drivers are intracellular proteins, constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented by…”
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Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs
Published in Nature (London) (23-11-2023)“…Following the publication of our manuscript, a new high-resolution structure of the HLA-A·24:02/PHOX2B peptide/10LH scFv complex by X-ray crystallography…”
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Two Dictyostelium Orthologs of the Prokaryotic Cell Division Protein FtsZ Localize to Mitochondria and Are Required for the Maintenance of Normal Mitochondrial Morphology
Published in Eukaryotic Cell (01-12-2003)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
Published in Science immunology (01-12-2023)“…Peptide-centric chimeric antigen receptors (PC-CARs) recognize oncoprotein epitopes displayed by cell-surface human leukocyte antigens (HLAs) and offer a…”
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The maturation of antibody technology for the HIV epidemic
Published in Immunology and cell biology (01-08-2014)“…Antibodies are one of our most useful biological tools. Indeed, improvements in antibody‐based technologies have ushered in a new era of antibody‐based…”
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Diverse Eukaryotes have Retained Mitochondrial Homologues of the Bacterial Division Protein FtsZ
Published in Protist (01-03-2004)“…Mitochondrial fission requires the division of both the inner and outer mitochondrial membranes. Dynamin-related proteins operate in division of the outer…”
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RETRACTED ARTICLE: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs
Published in Nature (London) (18-11-2021)“…The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented…”
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Cell Biology of Mitochondrial Dynamics
Published in International Review of Cytology (01-01-2006)“…Mitochondria are the product of an ancient endosymbiotic event between an alpha-proteobacterium and an archael host. An early barrier to overcome in this…”
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Erratum: Novel high-affinity EGFRvIII-specific chimeric antigen receptor T cells effectively eliminate human glioblastoma
Published in Clinical & translational immunology (2021)“…[This corrects the article DOI: 10.1002/cti2.1283.]…”
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