Search Results - "Kiebist, Jan"

Peroxide-Mediated Oxygenation of Organic Compounds by Fungal Peroxygenases by Hofrichter, Martin, Kellner, Harald, Herzog, Robert, Karich, Alexander, Kiebist, Jan, Scheibner, Katrin, Ullrich, René

“…Unspecific peroxygenases (UPOs), whose sequences can be found in the genomes of thousands of filamentous fungi, many yeasts and certain fungus-like protists,…”
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From Alkanes to Carboxylic Acids: Terminal Oxygenation by a Fungal Peroxygenase by Olmedo, Andrés, Aranda, Carmen, del Río, José C., Kiebist, Jan, Scheibner, Katrin, Martínez, Angel T., Gutiérrez, Ana

“…A new heme–thiolate peroxidase catalyzes the hydroxylation of n‐alkanes at the terminal position—a challenging reaction in organic chemistry—with H2O2 as the…”
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Synthesis of cyclophosphamide metabolites by a peroxygenase from Marasmius rotula for toxicological studies on human cancer cells by Steinbrecht, Susanne, Kiebist, Jan, König, Rosalie, Thiessen, Markus, Schmidtke, Kai-Uwe, Kammerer, Sarah, Küpper, Jan-Heiner, Scheibner, Katrin

“…Cyclophosphamide (CPA) represents a widely used anti-cancer prodrug that is converted by liver cytochrome P450 (CYP) enzymes into the primary metabolite…”
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Vesicle-based cell-free synthesis of short and long unspecific peroxygenases by Walter, Ruben Magnus, Zemella, Anne, Schramm, Marina, Kiebist, Jan, Kubick, Stefan

“…Unspecific peroxygenases (UPOs, EC 1.11.2.1) are fungal enzymes that catalyze the oxyfunctionalization of non-activated hydrocarbons, making them valuable…”
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High Epoxidation Yields of Vegetable Oil Hydrolyzates and Methyl Esters by Selected Fungal Peroxygenases by González-Benjumea, Alejandro, Marques, Gisela, Herold-Majumdar, Owik M, Kiebist, Jan, Scheibner, Katrin, Del Río, José C, Martínez, Angel T, Gutiérrez, Ana

“…Epoxides of vegetable oils and free and methylated fatty acids are of interest for several industrial applications. In the present work, refined rapeseed,…”
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Enzymatic Epoxidation of Long-Chain Terminal Alkenes by Fungal Peroxygenases by Babot, Esteban D, Aranda, Carmen, Kiebist, Jan, Scheibner, Katrin, Ullrich, René, Hofrichter, Martin, Martínez, Angel T, Gutiérrez, Ana

“…Terminal alkenes are among the most attractive starting materials for the synthesis of epoxides, which are essential and versatile intermediate building blocks…”
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Novel Unspecific Peroxygenase from Truncatella angustata Catalyzes the Synthesis of Bioactive Lipid Mediators by König, Rosalie, Kiebist, Jan, Kalmbach, Johannes, Herzog, Robert, Schmidtke, Kai-Uwe, Kellner, Harald, Ullrich, René, Jehmlich, Nico, Hofrichter, Martin, Scheibner, Katrin

“…Lipid mediators, such as epoxidized or hydroxylated eicosanoids (EETs, HETEs) of arachidonic acid (AA), are important signaling molecules and play diverse…”
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Cell-Free Protein Synthesis with Fungal Lysates for the Rapid Production of Unspecific Peroxygenases by Schramm, Marina, Friedrich, Stephanie, Schmidtke, Kai-Uwe, Kiebist, Jan, Panzer, Paul, Kellner, Harald, Ullrich, René, Hofrichter, Martin, Scheibner, Katrin

“…Unspecific peroxygenases (UPOs, EC 1.11.2.1) are fungal biocatalysts that have attracted considerable interest for application in chemical syntheses due to…”
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Biocatalytic Syntheses of Antiplatelet Metabolites of the Thienopyridines Clopidogrel and Prasugrel Using Fungal Peroxygenases by Kiebist, Jan, Schmidtke, Kai-Uwe, Schramm, Marina, König, Rosalie, Quint, Stephan, Kohlmann, Johannes, Zuhse, Ralf, Ullrich, René, Hofrichter, Martin, Scheibner, Katrin

“…Antithrombotic thienopyridines, such as clopidogrel and prasugrel, are prodrugs that undergo a metabolic two-step bioactivation for their pharmacological…”
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Unspezifische Peroxygenasen — Oxyfunktionalisierung außerhalb der Pilzhyphe by Scheibner, Katrin, Ullrich, René, Kiebist, Jan, Kellner, Harald, Hofrichter, Martin

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From Alkanes to Carboxylic Acids: Terminal Oxygenation by a Fungal Peroxygenase by Olmedo, Andrés, Aranda, Carmen, del Río, José C., Kiebist, Jan, Scheibner, Katrin, Martínez, Angel T., Gutiérrez, Ana

“…A new heme–thiolate peroxidase catalyzes the hydroxylation of n‐alkanes at the terminal position—a challenging reaction in organic chemistry—with H2O2 as the…”
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Functional Expression of Two Unusual Acidic Peroxygenases from Candolleomyces aberdarensis in Yeasts by Adopting Evolved Secretion Mutations by Gomez de Santos, Patricia, Hoang, Manh Dat, Kiebist, Jan, Kellner, Harald, Ullrich, René, Scheibner, Katrin, Hofrichter, Martin, Liers, Christiane, Alcalde, Miguel

“…Fungal unspecific peroxygenases (UPOs) are emergent biocatalysts that perform highly selective C-H oxyfunctionalizations of organic compounds, yet their…”
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A Peroxygenase from Chaetomium globosum Catalyzes the Selective Oxygenation of Testosterone by Kiebist, Jan, Schmidtke, Kai‐Uwe, Zimmermann, Jörg, Kellner, Harald, Jehmlich, Nico, Ullrich, René, Zänder, Daniel, Hofrichter, Martin, Scheibner, Katrin

“…Unspecific peroxygenases (UPO, EC 1.11.2.1) secreted by fungi open an efficient way to selectively oxyfunctionalize diverse organic substrates, including…”
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Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids by Gomez de Santos, Patricia, González‐Benjumea, Alejandro, Fernandez‐Garcia, Angela, Aranda, Carmen, Wu, Yinqi, But, Andrada, Molina‐Espeja, Patricia, Maté, Diana M., Gonzalez‐Perez, David, Zhang, Wuyuan, Kiebist, Jan, Scheibner, Katrin, Hofrichter, Martin, Świderek, Katarzyna, Moliner, Vicent, Sanz‐Aparicio, Julia, Hollmann, Frank, Gutiérrez, Ana, Alcalde, Miguel

“…The hydroxylation of fatty acids is an appealing reaction in synthetic chemistry, although the lack of selective catalysts hampers its industrial…”
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Early-stage sustainability assessment of enzyme production in the framework of lignocellulosic biorefinery by Bello, Sara, Pérez, Noelia, Kiebist, Jan, Scheibner, Katrin, Sánchez Ruiz, María Isabel, Serrano, Ana, Martínez, Ángel T., Feijoo, Gumersindo, Moreira, Maria Teresa

“…The use and integration of enzymatic processes for the biotransformation of biomass within the biorefinery framework creates the need to confirm whether these…”
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Selective Oxygenation of Ionones and Damascones by Fungal Peroxygenases by Babot, Esteban D, Aranda, Carmen, del Rı́o, José C, Ullrich, René, Kiebist, Jan, Scheibner, Katrin, Hofrichter, Martin, Martı́nez, Angel T, Gutiérrez, Ana

“…Apocarotenoids are among the most highly valued fragrance constituents, being also appreciated as synthetic building blocks. This work shows the ability of…”
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Fatty Acid Chain Shortening by a Fungal Peroxygenase by Olmedo, Andrés, Río, José C. del, Kiebist, Jan, Ullrich, René, Hofrichter, Martin, Scheibner, Katrin, Martínez, Angel T., Gutiérrez, Ana

“…A recently discovered peroxygenase from the fungus Marasmius rotula (MroUPO) is able to catalyze the progressive one‐carbon shortening of medium and long‐chain…”
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Singlet‐Oxygen Generation by Peroxidases and Peroxygenases for Chemoenzymatic Synthesis by Ingenbosch, Kim N., Quint, Stephan, Dyllick‐Brenzinger, Melanie, Wunschik, Dennis S., Kiebist, Jan, Süss, Philipp, Liebelt, Ute, Zuhse, Ralf, Menyes, Ulf, Scheibner, Katrin, Mayer, Christian, Opwis, Klaus, Gutmann, Jochen S., Hoffmann‐Jacobsen, Kerstin

“…Singlet oxygen is a reactive oxygen species undesired in living cells but a rare and valuable reagent in chemical synthesis. We present a fluorescence…”
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Selective Epoxidation of Fatty Acids and Fatty Acid Methyl Esters by Fungal Peroxygenases by Aranda, Carmen, Olmedo, Andrés, Kiebist, Jan, Scheibner, Katrin, del Río, José C., Martínez, Angel T., Gutiérrez, Ana

“…Recently discovered fungal unspecific peroxygenases from Marasmius rotula and Chaetomium globosum catalyze the epoxidation of unsaturated fatty acids (FA) and…”
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Unspezifische Peroxygenasen — Oxyfunktionalisierung außerhalb der Pilzhyphe by Scheibner, Katrin, Ullrich, René, Kiebist, Jan, Kellner, Harald, Hofrichter, Martin

“…Unspecific peroxygenases (UPOs) secreted by fungi represent an intriguing enzyme type that selectively transfers peroxide-borne oxygen with high efficiency to…”
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