Search Results - "Kidson, S. H."
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An evaluation of molecular markers for improved detection of breast cancer metastases in sentinel nodes
Published in Journal of clinical pathology (01-03-2006)“…Background and objectives: In patients with breast cancer (BC), the sentinel node (SN) is the first node in the axillary basin that receives the primary…”
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A rare repigmentation pattern in a vitiligo patient: a clue to an epidermal stem-cell reservoir of melanocytes?
Published in Clinical and experimental dermatology (01-03-2009)Get full text
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Molecular analysis of vitiligo lesions reveals sporadic melanocyte survival
Published in International journal of dermatology (01-03-2007)“…Vitiligo is a depigmenting disease of uncertain aetio‐pathogenesis. Although accepted as dogma, the question of whether melanocytes survive in vitiligo lesions…”
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Towards guidelines for informed consent for prospective stem cell research
Published in South African Journal of Bioethics and Law (16-09-2015)“…Stem cell science is advancing at an unprecedented rate, with thousands of research papers being published every year and many clinical trials for a wide range…”
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Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development
Published in Human molecular genetics (12-04-2000)“…Anterior segment developmental disorders, including Axenfeld-Rieger anomaly (ARA), variably associate with harmfully elevated intraocular pressure (IOP), which…”
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KUVA (khellin plus ultraviolet A) stimulates proliferation and melanogenesis in normal human melanocytes and melanoma cells in vitro
Published in British journal of dermatology (1951) (01-10-2003)“…Summary Background Khellin is a naturally occurring furochromone which, when combined with artificial ultraviolet (UV) A or solar irradiation (KUVA), is…”
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Proliferation and cell shape changes during ciliary body morphogenesis in the mouse
Published in Developmental dynamics (01-05-2005)“…Very little is known about the structure and development of the ciliary processes in the mouse eye. Our scanning electron microscope (SEM) studies reveal that,…”
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The rise of developmental genetics - a historical account of the fusion of embryology and cell biology with human genetics and the emergence of the Stem Cell Initiative
Published in South African medical journal (25-05-2016)“…Genetics and cell biology are very prominent areas of biological research with rapid advances being driven by a flood of theoretical, technological and…”
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Advances in imaging the blood and aqueous vessels of the ocular limbus
Published in Experimental eye research (01-08-2010)“…The vessels of the limbus play a pivotal role in the drainage of the major portion of aqueous humour from the anterior chamber. Aberrations in the limbal…”
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Accurate molecular detection of melanoma nodal metastases: an assessment of multimarker assay specificity, sensitivity, and detection rate
Published in Molecular pathology (01-02-2003)“…Background: The application of lymphoscintigraphy followed by sentinel lymph node (SN) biopsy to patients with primary melanoma has revolutionised the ability…”
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Stem cell transplantation: a collegial conversation
Published in South African medical journal (01-01-2013)“…To assist our readers in their understanding of ''Pioneer' Paarl neuro sets alarm bells ringing' in Izindaba (p. 8-9), the SAMJ sought the opinions of…”
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A new class of stem cells in South Africa: iPS cells
Published in South African medical journal (01-01-2013)“…Created from adult rather than embryonic cells, induced pluripotent stem (iPS) cells represent a breakthrough in stem cell science, and their pioneers have…”
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Molecular events in early development of the ciliary body: A question of folding
Published in Experimental eye research (01-04-2007)“…Ciliary body morphogenesis is a complicated, multi-step process requiring coordinated changes in cell shape, flexure of epithelial sheets and dynamic shifts in…”
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The detection of circulating melanoma cells correlates with tumour thickness and ulceration but is not predictive of metastasis for patients with primary melanoma
Published in Melanoma research (01-10-1999)“…We analysed peripheral blood samples from 143 patients with primary melanoma (PM) for the presence of tyrosinase mRNA by reverse transcription-polymerase chain…”
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TYPES OF ALBINISM IN THE BLACK SOUTHERN AFRICA POPULATION
Published in East African medical journal (01-01-2012)“…Oculocutaneous albinism (OCA) is the most common inherited disorder in Southern African blacks and several types have been described. Molecular techniques,…”
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SV-40 LARGE T ANTIGEN REVERSIBLY INHIBITS EXPRESSION OF TYROSINASE, TRP-1, TRP-2 AND MITF, BUT NOT PAX-3, IN CONDITIONALLY IMMORTALIZED MOUSE MELANOCYTES
Published in Cell biology international (01-01-2001)“…Transformation of mouse melanocytes with a variety of exogenous oncogenes or chemical carcinogens frequently results in irreversible loss of pigmentation. We…”
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Cytokine-mediated Inhibition of Erythropoietin Synthesis by Dexamethasone
Published in Journal of pharmacy and pharmacology (01-09-1996)“…The effect of inflammatory cytokines on the in‐vitro synthesis of erythropoietin by HepG2 cells was evaluated. Monocyte‐conditioned medium, and the cytokines…”
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The Forkhead/Winged-Helix Gene, Mf1, Is Necessary for the Normal Development of the Cornea and Formation of the Anterior Chamber in the Mouse Eye
Published in Developmental biology (15-07-1999)“…Mf1, which encodes a winged-helix/forkhead transcription factor, is the murine homolog of human FKHL7, mutated in individuals with autosomal dominant inherited…”
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An improved and combined reverse transcription-polymerase chain reaction assay for reliable detection of metastatic melanoma cells in peripheral blood
Published in Melanoma research (01-04-1997)“…The application of reverse transcription-polymerase chain reaction (RT-PCR) for detection of metastatic melanoma cells in peripheral blood has been used by a…”
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The Cloning and Characterization of Chick Tyrosinase from a Novel Embryonic cDNA Library
Published in Experimental cell research (01-05-1996)“…Very little is known about the genes involved in the regulation of avian skin and feather pigmentation. In mammals, two gene families have been identified as…”
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