Search Results - "Kidd, Vincent J"

Potentiation of neuroblastoma metastasis by loss of caspase-8 by Stupack, Dwayne G, Lahti, Jill M, Teitz, Tal, Potter, Matthew D, Mikolon, David, Houghton, Peter J, Kidd, Vincent J, Cheresh, David A

“…Neuroblastoma, the most common paediatric solid tumour, arises from defective neural crest cells. Genetic alterations occur frequently in the most aggressive…”
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ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53 by Tang, Damu, Wu, Dongcheng, Hirao, Atsushi, Lahti, Jill M., Liu, Lieqi, Mazza, Brie, Kidd, Vincent J., Mak, Tak W., Ingram, Alistair J.

“…In response to DNA damage, ataxia-telangiectasia mutant and ataxia-telangiectasia and Rad-3 activate p53, resulting in either cell cycle arrest or apoptosis…”
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Loss of ChlR1 Helicase in Mouse Causes Lethality Due to the Accumulation of Aneuploid Cells Generated by Cohesion Defects and Placental Malformation by Inoue, Akira, Li, Tongyuan, Roby, Sarah K., Valentine, Marcus B., Inoue, Madoka, Boyd, Kelli, Kidd, Vincent J., Lahti, Jill M.

“…Human DDX11 and DDX12 are closely related genes encoding the helicases ChlR1 and ChlR2, which belong to the CHL1 DNA helicase family. Recently, it was shown…”
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Dopaminergic cell death induced by MPP+, oxidant and specific neurotoxicants shares the common molecular mechanism by . Chun, Hong S, Gibson, Gary E., DeGiorgio, Lorraine A., Zhang, H., Kidd, Vincent J., Son, Jin H.

“…Recent etiological study in twins (Tanner et al. 1999) strongly suggests that environmental factors play an important role in typical, non‐familial Parkinson's…”
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CDK11 Complexes Promote Pre-mRNA Splicing by Hu, Dongli, Mayeda, Akila, Trembley, Janeen H, Lahti, Jill M, Kidd, Vincent J

“…The PITSLRE protein kinases, hereafter referred to as CDK11 because of their association with the cyclin L regulatory partner, belong to large molecular weight…”
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Apoptotic Release of Histones from Nucleosomes by Wu, Dongcheng, Ingram, Alistair, Lahti, Jill H., Mazza, Brie, Grenet, Jose, Kapoor, Anil, Liu, Lieqi, Kidd, Vincent J., Tang, Damu

“…Chromatin structure is influenced by histone modification, and this may help direct chromatin behavior to facilitate transcription, DNA replication, and DNA…”
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ASAP, a Novel Protein Complex Involved in RNA Processing and Apoptosis by Schwerk, Christian, Prasad, Jayendra, Degenhardt, Kurt, Erdjument-Bromage, Hediye, White, Eileen, Tempst, Paul, Kidd, Vincent J., Manley, James L., Lahti, Jill M., Reinberg, Danny

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Activation of Pre-mRNA Splicing by Human RNPS1 Is Regulated by CK2 Phosphorylation by Trembley, Janeen H., Tatsumi, Sawako, Sakashita, Eiji, Loyer, Pascal, Slaughter, Clive A., Suzuki, Hitoshi, Endo, Hitoshi, Kidd, Vincent J., Mayeda, Akila

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Casein Kinase 2 Interacts with Cyclin-dependent Kinase 11 (CDK11) in Vivo and Phosphorylates Both the RNA Polymerase II Carboxyl-terminal Domain and CDK11 in Vitro by Trembley, Janeen H, Hu, Dongli, Slaughter, Clive A, Lahti, Jill M, Kidd, Vincent J

“…The PITSLRE protein kinases, hereafter referred to as cyclin-dependent kinase 11 (CDK11) due to their association with cyclin L, are part of large molecular…”
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PITSLRE p110 Protein Kinases Associate with Transcription Complexes and Affect Their Activity by Trembley, Janeen H., Hu, Dongli, Hsu, Li-Chung, Yeung, Cho-Yau, Slaughter, Clive, Lahti, Jill M., Kidd, Vincent J.

“…Although the PITSLRE protein kinases are members of the cyclin-dependent kinase superfamily, their cellular function is unclear. Previously we demonstrated…”
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CDK11p⁵⁸ is required for the maintenance of sister chromatid cohesion by Hu, Dongli, Valentine, Marcus, Kidd, Vincent J, Lahti, Jill M

“…Cyclin-dependent kinase 11 (CDK11) mRNA produces a 110-kDa protein (CDK11p¹¹⁰) throughout the cell cycle and a 58-kDa protein (CDK11p⁵⁸) that is specifically…”
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CDK11(p58) is required for the maintenance of sister chromatid cohesion by Hu, Dongli, Valentine, Marcus, Kidd, Vincent J, Lahti, Jill M

“…Cyclin-dependent kinase 11 (CDK11) mRNA produces a 110-kDa protein (CDK11(p110)) throughout the cell cycle and a 58-kDa protein (CDK11(p58)) that is…”
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Characterization of Cyclin L1 and L2 Interactions with CDK11 and Splicing Factors: INFLUENCE OF CYCLIN L ISOFORMS ON SPLICE SITE SELECTION by Loyer, Pascal, Trembley, Janeen H, Grenet, Jose A, Busson, Adeline, Corlu, Anne, Zhao, Wei, Kocak, Mehmet, Kidd, Vincent J, Lahti, Jill M

“…Although it has been reported that cyclin L1α and L2α proteins interact with CDK11p¹¹⁰, the nature of the cyclin L transcripts, the formation of complexes…”
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Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN by Kidd, Vincent J, Teitz, Tal, Wei, Tie, Valentine, Marcus B, Vanin, Elio F, Grenet, Jose, Valentine, Virginia A, Behm, Frederick G, Look, A. Thomas, Lahti, Jill M

“…Caspase 8 is a cysteine protease regulated in both a death-receptor-dependent and -independent manner during apoptosis. Here, we report that the gene for…”
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Proteolytic activities that mediate apoptosis by Kidd, V J

“…Since the discovery that cells can activate their own suicide program, investigators have attempted to determine whether the events that are associated with…”
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Role of CDK/cyclin complexes in transcription and RNA splicing by Loyer, Pascal, Trembley, Janeen H., Katona, Robert, Kidd, Vincent J., Lahti, Jill M.

“…The production of mRNAs in all living organisms is an extremely complex process that includes multiple catalytic activities such as transcription, capping,…”
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Caspase-8 Activation and Bid Cleavage Contribute to MCF7 Cellular Execution in a Caspase-3-dependent Manner during Staurosporine-mediated Apoptosis by Tang, Damu, Lahti, Jill M., Kidd, Vincent J.

“…There are at least two distinct classes of caspases, initiators (e.g. caspases-8, -9, and -10) and effectors (e.g. caspase-3). Furthermore, it is believed that…”
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The Murine G+C-Rich Promoter Binding Protein mGPBP Is Required for Promoter-Specific Transcription by Hsu, Li-Chung, Liu, Shu, Abedinpour, Ferishteh, Beech, Robert D., Lahti, Jill M., Kidd, Vincent J., Greenspan, Jeffrey A., Yeung, Cho-Yau

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Cleavage of DFF-45/ICAD by Multiple Caspases Is Essential for Its Function during Apoptosis by Tang, Damu, Kidd, Vincent J.

“…Apoptosis involves the proteolysis of specific cellular proteins by a group of cysteine proteases known as caspases. Many of these cellular targets are either…”
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Mutant p53 Cooperates with ETS and Selectively Up-regulates Human MDR1 Not MRP1 by Sampath, Janardhan, Sun, Daxi, Kidd, Vincent J., Grenet, Jose, Gandhi, Amisha, Shapiro, Linda H., Wang, Qingjian, Zambetti, Gerard P., Schuetz, John D.

“…The most frequently expressed drug resistance genes, MDR1 and MRP1, occur in human tumors with mutant p53. However, it was unknown if mutant p53…”
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