Liposomes loaded with lipophilic derivative of closo-carborane as a potential boron delivery system for boron neutron capture therapy of tumors

[Display omitted] Liposomes encapsulated with lipophilic derivative of 1,2-dicarba-closo-dodecaborane have been obtained and tested for toxicity to glioblastoma U87 cells and biodistribution on a U87MG xenograft mouse model. The liposomes are able to penetrate the tumor and provide boron concentrati...

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Bibliographic Details

Published in:	Mendeleev communications Vol. 31; no. 5; pp. 659 - 661
Main Authors:	Tsygankova, Alphiya R., Gruzdev, Dmitry A., Kanygin, Vladimir V., Ya. Guselnikova, Tatiana, Telegina, Angelina A., Kasatova, Anna I., Kichigin, Aleksandr I., Levit, Galina L., Mechetina, Ludmila V., Mukhamadiyarov, Rinat A., Razumov, Ivan A., Solovieva, Olga I., Yu. Volkova, Olga, Ponomarev, Andrey A., Krasnov, Victor P., Zavjalov, Evgenii L.
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01-09-2021
Subjects:	amide biodistribution BNCT closo-carborane liposomes toxicity U87 tumor model toxicity biodistribution BNCT amide liposomes closo-carborane U87 tumor model
Online Access:	Get full text
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