Search Results - "Kibler, D."
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De novo design of protein logic gates
Published in Science (American Association for the Advancement of Science) (03-04-2020)“…The design of modular protein logic for regulating protein function at the posttranscriptional level is a challenge for synthetic biology. Here, we describe…”
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De novo design of knotted tandem repeat proteins
Published in Nature communications (24-10-2023)“…De novo protein design methods can create proteins with folds not yet seen in nature. These methods largely focus on optimizing the compatibility between the…”
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Novel Role of Macrophage Migration Inhibitory Factor in Upstream Control of the Unfolded Protein Response After Ethanol Feeding in Mice
Published in Alcoholism, clinical and experimental research (01-07-2019)“…Background Macrophage migration inhibitory factor (MIF), a pluripotent immune regulator, is an emerging mediator in alcohol‐related liver disease (ALD). MIF is…”
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Relations between hydrology and velocity of a continuously moving landslide--evidence of pore-pressure feedback regulating landslide motion
Published in Landslides (01-09-2009)“…We measured displacement, pore-water pressure, and climatic conditions for 3 years at the continuously moving Slumgullion landslide in Colorado, USA. The…”
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Genetically Encoded XTEN‐based Hydrogels with Tunable Viscoelasticity and Biodegradability for Injectable Cell Therapies
Published in Advanced science (01-06-2024)“…While direct cell transplantation holds great promise in treating many debilitating diseases, poor cell survival and engraftment following injection have…”
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Role of MIF in coordinated expression of hepatic chemokines in patients with alcohol-associated hepatitis
Published in JCI insight (08-06-2021)“…The chemokine system of ligands and receptors is implicated in the progression of alcohol-associated hepatitis (AH). Finding upstream regulators could lead to…”
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Hallucinating symmetric protein assemblies
Published in Science (American Association for the Advancement of Science) (07-10-2022)“…Deep learning generative approaches provide an opportunity to broadly explore protein structure space beyond the sequences and structures of natural proteins…”
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Seasonal movement of the Slumgullion landslide determined from Global Positioning System surveys and field instrumentation, July 1998–March 2002
Published in Engineering geology (01-02-2003)“…Measurements of landslide movement made by global positioning system surveys and extensometers over a 3.5-year period show that the Slumgullion landslide in…”
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Novel biphasic gels can mimic and replace animal fat in fully-cooked coarse-ground sausage
Published in Meat science (01-12-2022)“…Four biphasic gels (BPG) were developed and tested as pork fat replacers in coarse-ground fully-cooked sausages. An oleogel (OG) phase (92.5% high-oleic…”
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10
Precisely patterned nanofibres made from extendable protein multiplexes
Published in Nature chemistry (01-12-2023)“…Molecular systems with coincident cyclic and superhelical symmetry axes have considerable advantages for materials design as they can be readily lengthened or…”
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Blueprinting extendable nanomaterials with standardized protein blocks
Published in Nature (London) (28-03-2024)“…A wooden house frame consists of many different lumber pieces, but because of the regularity of these building blocks, the structure can be designed using…”
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A concise review of lobster utilization by worldwide human populations from prehistory to the modern era
Published in ICES journal of marine science (01-07-2015)“…Abstract Lobsters are important resources throughout the world's oceans, providing food security, employment, and a trading commodity. Whereas marine…”
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Site-specific Substitutions Eliminate Aggregation Properties of Hemopressin
Published in Chemical biology & drug design (01-12-2015)“…Hemopressin is a naturally occurring and therapeutically relevant peptide with applications in hypertension, pain, addiction, and obesity. We had previously…”
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CONSTRUCTING A PROBLEM SOLVING ENVIRONMENT TOOL FOR HYDROLOGIC ASSESSMENT OF LAND USE CHANGE
Published in Journal of the American Water Resources Association (01-04-2002)“…Using the Back Creek watershed in the upper Roanoke River basin, VA, as the study area, a graphically based, user-friendly, web-enabled Problem Solving…”
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Hydrological and Fiscal Impacts of Residential Development: Virginia Case Study
Published in Journal of water resources planning and management (01-03-2003)“…This study examined hydrological and fiscal effects of residential growth patterns in Virginia. Eleven scenarios that consider a fixed increase in population…”
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From landscapes to waterscapes: A PSE for landuse change analysis
Published in Engineering with computers (01-07-2003)“…We describe the design and implementation of L2W - a Problem Solving Environment (PSE) for landuse change analysis. L2W organizes and unifies the diverse…”
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Sizing Storm-Water Detention Basins for Pollutant Removal
Published in Journal of environmental engineering (New York, N.Y.) (1994)“…A statistical formulation for estimating the average time of detention within a pond for a captured runoff volume is presented. For a conservative estimator,…”
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Integrated Computing Environments for Watershed Management
Published in Journal of computing in civil engineering (01-10-2002)“…This paper describes a new computing paradigm known as a problem solving environment (PSE), explores the role this new paradigm might play in watershed…”
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Using hexamers to predict cis-regulatory motifs in Drosophila
Published in BMC bioinformatics (27-10-2005)“…Cis-regulatory modules (CRMs) are short stretches of DNA that help regulate gene expression in higher eukaryotes. They have been found up to 1 megabase away…”
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Necessary and sufficient conditions for the existence of the modular Fourier transform: Comments on "Number theoretic transforms to implement fast digital convolution"
Published in Proceedings of the IEEE (01-02-1977)“…A correct proof of Theorem 2 from the paper "Number Theoretic Transforms to Implement Fast Digital Convolutions," giving necessary and sufficient conditions…”
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