Search Results - "Kibble, J. D."

Volume regulation is defective in renal proximal tubule cells isolated from KCNE1 knockout mice by Millar, I. D., Hartley, J. A., Haigh, C., Grace, A. A., White, S. J., Kibble, J. D., Robson, L.

“…The membrane protein KCNE1 has been implicated in cell volume regulation. Using a knockout mouse model, this study examined the role of KCNE1 in regulatory…”
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Renal defects in KCNE1 knockout mice are mimicked by chromanol 293B in vivo: identification of a KCNE1‐regulated K+ conductance in the proximal tubule by Neal, A. M., Taylor, H. C., Millar, I. D., Kibble, J. D., White, S. J., Robson, L.

“…Non‐technical summary  The kidney plays a critical role in regulating body fluid volume and blood pressure by conserving ions, solutes and water. Knowing the…”
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Whole cell Cl- conductances in mouse choroid plexus epithelial cells do not require CFTR expression by Kibble, J D, Garner, C, Colledge, W H, Brown, S, Kajita, H, Evans, M, Brown, P D

“…Whole cell patch-clamp studies were performed with tissue isolated from the cystic fibrosis (CF) transgenic Cftrm1cam mouse, to determine whether anion…”
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Evidence for cystic fibrosis transmembrane conductance regulator-dependent sodium reabsorption in kidney, using Cftr(tm2cam) mice by Kibble, J D, Neal, A M, Colledge, W H, Green, R, Taylor, C J

“…The aims of this study were to investigate (a) if renal Na(+) handling was normal in Cftr(tm2cam) delta F508 cystic fibrosis mice, (b) whether adaptation to…”
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Improved analysis of picomole quantities of lithium, sodium, and potassium in biological fluids by Shalmi, M, Kibble, J D, Day, J P, Christensen, P, Atherton, J C

“…The analysis of picomolar lithium, sodium, and potassium by electrothermal atomic absorption spectrophotometry was studied using a Perkin-Elmer Zeeman 3030…”
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Estimated potassium reflection coefficient in perfused proximal convoluted tubules of the anaesthetized rat in vivo by Wareing, M, Wilson, R W, Kibble, J D, Green, R

“…1. As yet there is no definitive description of the mechanism and route by which K+ reabsorption is achieved in the proximal convoluted tubule (PCT). We have…”
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Evidence for cystic fibrosis transmembrane conductance regulator-dependent sodium reabsorption in kidney, using Cftrtm2cammice by Kibble, J. D., Neal, A. M., Colledge, W. H., Green, R., Taylor, C. J.

“…The aims of this study were to investigate (a) if renal Na + handling was normal in Cftr tm2cam ΔF508 cystic fibrosis mice, (b) whether adaptation to dietary…”
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A hypertonicity-activated nonselective conductance in single proximal tubule cells isolated from mouse kidney by Balloch, K J D, Hartley, J A, Millar, I D, Kibble, J D, Robson, L

“…The whole-cell patch-clamp technique was used to examine nonselective conductances in single proximal tubule cells isolated from mouse kidney. Single cells…”
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Adaptive downregulation of a quinidine-sensitive cation conductance in renal principal cells of TWIK-1 knockout mice by Millar, I D, Taylor, H C, Cooper, G J, Kibble, J D, Barhanin, J, Robson, L

“…TWIK-1, a member of the two-pore domain K(+) channel family, is expressed in brain, kidney, and lung. The aim of this study was to examine the effect of loss…”
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Effect of barium on potassium diffusion across the proximal convoluted tubule of the anesthetized rat by Kibble, J D, Wareing, M, Wilson, R W, Green, R

“…The role of diffusion in transepithelial potassium flux and the importance of potassium channels in the luminal cell membrane to this process were examined by…”
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Kir2.3-like K⁺ Conductance in Mouse Cortical Collecting Duct Principal Cells by Millar, I.D, Taylor, H.C, Cooper, G.J, Kibble, J.D, Robson, L

“…K⁺ channels play an important role in renal collecting duct cell function. The current study examined barium (Ba²⁺)-sensitive whole-cell K⁺ currents (IKBa) in…”
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Dose-response effects of adrenergic and cholinergic stimulation on atrial natriuretic peptide secretion from beating isolated guinea-pig atria by Speake, P F, Pirie, S C, Kibble, J D, Muneer, A, Taylor, D, Birring, S, Green, R

“…1. The possible role of autonomic neurotransmitters in atrial natriuretic peptide secretion was investigated using spontaneously beating guinea-pig atria in…”
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A new protocol for the measurement of picomole quantities of magnesium in rat renal tubular fluid by Kibble, J D, Audsley, N, Day, J P, Green, R

“…The analysis of picomolar quantities of magnesium by electrothermal atomic absorption spectrophotometry (EAAS) was studied using a Perkin-Elmer-Zeeman 3030…”
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Renal proximal tubule function is preserved in Cftrtm2camΔF508 cystic fibrosis mice by Kibble, J. D., Balloch, K. J. D., Neal, A. M., Hill, C., White, S., Robson, L., Green, R., Taylor, C. J.

“…1 Changes in proximal tubule function have been reported in cystic fibrosis patients. The aim of this study was to investigate proximal tubule function in the…”
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Properties of the cAMP-activated C1- current in choroid plexus epithelial cells isolated from the rat by Kibble, J D, Trezise, A E, Brown, P D

“…1. This study used whole-cell patch clamp and RNA in situ hybridization experiments to determine whether the cAMP-activated C1- current expressed in choroid…”
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Model explaining the relation between distal nephron Li+ reabsorption and urinary Na+ excretion in rats by Shalmi, M, Jonassen, T, Thomsen, K, Kibble, J D, Bie, P, Christensen, S

“…Li+ may be reabsorbed via an amiloride-sensitive mechanism in the collecting ducts of rats administered a low-Na+ diet. This was investigated by measuring the…”
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A Ca2+-activated whole-cell Cl- conductance in human placental cytotrophoblast cells activated via a G protein by Kibble, J D, Greenwood, S L, Clarson, L H, Sibley, C P

“…Whole-cell patch clamp experiments were performed on cultured human cytotrophoblast cells incubated for 24-48 hr after their isolation from term placentas…”
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Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells by Speake, Tracey, Kibble, Jonathan D, Brown, Peter D

“…The choroid plexuses secrete, and maintain the composition of, the cerebrospinal fluid. K+ channels play an important role in these processes. In this study…”
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Evidence for cystic fibrosis transmembrane conductance regulator‐dependent sodium reabsorption in kidney, using Cftr tm2cam mice by Kibble, J. D., Neal, A. M., Colledge, W. H., Green, R., Taylor, C. J.

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Renal proximal tubule function is preserved in Cftr(tm2cam) deltaF508 cystic fibrosis mice by Kibble, J D, Balloch, K J, Neal, A M, Hill, C, White, S, Robson, L, Green, R, Taylor, C J

“…1. Changes in proximal tubule function have been reported in cystic fibrosis patients. The aim of this study was to investigate proximal tubule function in the…”
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