Search Results - "Kibbie, Jon J"
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Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFNγ Production From Human Colonic ILC3s via Multiple Mechanisms
Published in Frontiers in immunology (29-03-2019)“…Innate lymphoid cells (ILCs) are a diverse family of cells that play critical roles in mucosal immunity. One subset of the ILC family, Group 3 ILCs (ILC3s),…”
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Journal Article -
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Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling
Published in Immunobiology (1979) (01-09-2021)“…An important function of the gut microbiome is the fermentation of non-digestible dietary fibers into short chain fatty acids (SCFAs). The three primary SCFAs:…”
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Journal Article -
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The number needed to biopsy for cutaneous melanoma in academic dermatology clinics
Published in Melanoma research (01-08-2024)“…A standard metric for melanoma detection is the number needed to biopsy (NNB). This metric has been used to evaluate practicing dermatologists, dermatology…”
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Journal Article -
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Age‐related alterations in human gut CD4 T cell phenotype, T helper cell frequencies, and functional responses to enteric bacteria
Published in Journal of leukocyte biology (01-01-2020)“…Intestinal lamina propria (LP) CD4 T cells play critical roles in maintaining intestinal homeostasis and in immune responses to enteric microbes, yet little is…”
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Journal Article -
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Immunomodulatory Effects of the Short Chain Fatty Acid Butyrate on Gut Mucosal T Cells in the Setting of HIV-1 Infection
Published 01-01-2019“…The gastrointestinal tract is profoundly affected during acute and chronic HIV-1 infection. Early in the course of the infection, there is a breakdown in gut…”
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Dissertation