Search Results - "Kibbe, W A"
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Cancer Moonshot Data and Technology Team: Enabling a National Learning Healthcare System for Cancer to Unleash the Power of Data
Published in Clinical pharmacology and therapeutics (01-05-2017)“…The Cancer Moonshot emphasizes the need to learn from the experiences of cancer patients to positively impact their outcomes, experiences, and qualities of…”
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OligoCalc: an online oligonucleotide properties calculator
Published in Nucleic acids research (01-07-2007)“…We developed OligoCalc as a web-accessible, client-based computational engine for reporting DNA and RNA single-stranded and double-stranded properties,…”
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Disease Ontology: a backbone for disease semantic integration
Published in Nucleic acids research (01-01-2012)“…The Disease Ontology (DO) database (http://disease-ontology.org) represents a comprehensive knowledge base of 8043 inherited, developmental and acquired human…”
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dictyBase update 2011: web 2.0 functionality and the initial steps towards a genome portal for the Amoebozoa
Published in Nucleic acids research (01-01-2011)“…dictyBase (http://www.dictybase.org), the model organism database for Dictyostelium, aims to provide the broad biomedical research community with well…”
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The SV40 core sequence functions as a repressor element in yeast
Published in The Journal of biological chemistry (15-11-1991)“…Our previous studies showed that the AP-1 recognition element (ARE) present within the SV40 72-base pair (bp) enhancer will activate transcription in yeast…”
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The Gene Ontology: enhancements for 2011
Published in Nucleic acids research (01-01-2012)“…The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of…”
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The Saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties
Published in Cell (13-02-1987)“…The heat shock transcription factor (HSTF) has been purified to apparent homogeneity from S. cerevisiae and D. melanogaster by sequence-specific DNA-affinity…”
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Generating a focused view of disease ontology cancer terms for pan-cancer data integration and analysis
Published in Database : the journal of biological databases and curation (04-04-2015)“…Bio-ontologies provide terminologies for the scientific community to describe biomedical entities in a standardized manner. There are multiple initiatives that…”
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Xanthusbase: adapting wikipedia principles to a model organism database
Published in Nucleic acids research (01-01-2007)“…xanthusBase () is the official model organism database (MOD) for the social bacterium Myxococcus xanthus. In many respects, M.xanthus represents the pioneer…”
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dictyBase: a new Dictyostelium discoideum genome database
Published in Nucleic acids research (01-01-2004)“…Dictyostelium discoideum is a powerful and genetically tractable model system used for the study of numerous cellular molecular mechanisms including…”
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Irrational exuberance in clinical proteomics
Published in Clinical cancer research (15-11-2005)Get full text
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Improved prediction of treatment response using microarrays and existing biological knowledge
Published in Pharmacogenomics (01-04-2006)“…A desired application for microarrays in the clinic is to predict treatment response from an often diverse patient population. We present a method for…”
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A genome end-game: understanding gene function in the nervous system
Published in Nature neuroscience (01-05-2004)Get full text
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Annotating nonspecific SAGE tags with microarray data
Published in Genomics (San Diego, Calif.) (2006)“…SAGE (serial analysis of gene expression) detects transcripts by extracting short tags from the transcripts. Because of the limited length, many SAGE tags are…”
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Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function
Published in Brain research. Molecular brain research. (20-12-2004)“…N-ethyl- N-nitrosourea (ENU) mutagenesis is presented as a powerful approach to developing models for human disease. The efforts of three NIH Mutagenesis…”
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Journal Article Conference Proceeding -
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Application of Wavelet Transform to the MS-based Proteomics Data Preprocessing
Published in 2007 IEEE 7th International Symposium on BioInformatics and BioEngineering (01-01-2007)“…Mass spectrometry (MS) has become one of the major detection technologies for high-throughput proteomics. The preprocessing of mass spectra is crucial for its…”
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Conference Proceeding Journal Article