Search Results - "Kibaly, Cherkaouia"

Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability by Kibaly, Cherkaouia, Alderete, Jacob A., Liu, Steven H., Nasef, Hazem S., Law, Ping-Yee, Evans, Christopher J., Cahill, Catherine M.

“…It is estimated that nearly a third of people who abuse drugs started with prescription opioid medicines. Approximately, 11.5 million Americans used…”
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Effects of inflammatory pain on CB1 receptor in the midbrain periaqueductal gray by Wilson-Poe, Adrianne R., Wiese, Beth, Kibaly, Cherkaouia, Lueptow, Lindsay, Garcia, Jeniffer, Anand, Preeti, Cahill, Catherine, Morón, Jose A.

“…The periaqueductal gray (PAG) mediates the antinociceptive properties of analgesics, including opioids and cannabinoids. Administration of either opioids or…”
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Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord by Kibaly, Cherkaouia, Meyer, Laurence, Patte-Mensah, Christine, Mensah-Nyagan, Ayikoe G

“…We investigated the role and mechanism of action of dehydroepiandrosterone (DHEA) produced by the spinal cord (SC) in pain modulation in sciatic-neuropathic…”
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Src‐dependent phosphorylation of μ‐opioid receptor at Tyr336 modulates opiate withdrawal by Zhang, Lei, Kibaly, Cherkaouia, Wang, Yu‐Jun, Xu, Chi, Song, Kyu Young, McGarrah, Patrick W, Loh, Horace H, Liu, Jing‐Gen, Law, Ping‐Yee

“…Opiate withdrawal/negative reinforcement has been implicated as one of the mechanisms for the progression from impulsive to compulsive drug use. Increase in…”
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Substance P Inhibits Progesterone Conversion to Neuroactive Metabolites in Spinal Sensory Circuit: A Potential Component of Nociception by Patte-Mensah, Christine, Kibaly, Cherkaouia, Mensah-Nyagan, Ayikoe G., Baulieu, Etienne-Emile

“…A crucial biochemical reaction in vertebrates is progesterone conversion into neuroactive metabolites such as dihydroprogesterone (5α-DHP) and…”
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Molecular and neurochemical evidence for the biosynthesis of dehydroepiandrosterone in the adult rat spinal cord by Kibaly, Cherkaouia, Patte‐Mensah, Christine, Mensah‐Nyagan, Ayikoe G.

“…Various studies have indicated that exogenous dehydroepiandrosterone (DHEA) modulates several mechanisms in the CNS of rodents. As adult rodent glands do not…”
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Neurogenic pain and steroid synthesis in the spinal cord by Patte-Mensah, Christine, Kibaly, Cherkaouia, Boudard, Domitille, Schaeffer, Véronique, Béglé, Aurélie, Saredi, Simona, Meyer, Laurence, Mensah-Nyagan, Ayikoe G

“…The spinal cord (SC) is a biosynthetic center for neurosteroids, including pregnenolone (PREG), progesterone (PROG), and 3alpha/5alpha-tetrahydroprogesterone…”
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Non-nociceptive roles of opioids in the CNS: opioids’ effects on neurogenesis, learning, memory and affect by Kibaly, Cherkaouia, Xu, Chi, Cahill, Catherine M., Evans, Christopher J., Law, Ping-Yee

“…Mortality due to opioid use has grown to the point where, for the first time in history, opioid-related deaths exceed those caused by car accidents in many…”
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Naltrexone Facilitates Learning and Delays Extinction by Increasing AMPA Receptor Phosphorylation and Membrane Insertion by Kibaly, Cherkaouia, Kam, Angel Y.F, Loh, Horace H, Law, Ping-Yee

“…Abstract Background The opioid antagonists naloxone/naltrexone are involved in improving learning and memory, but their cellular and molecular mechanisms…”
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Evidence for a key role of steroids in the modulation of pain by Mensah-Nyagan, Ayikoe G, Meyer, Laurence, Schaeffer, Véronique, Kibaly, Cherkaouia, Patte-Mensah, Christine

“…Summary Neurotransmitters such as glutamate, substance P, serotonin and gamma-aminobutyric acid pivotally control pain mechanisms. It is also well known that…”
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Spinal or supraspinal phosphorylation deficiency at the MOR C-terminus does not affect morphine tolerance in vivo by Kibaly, Cherkaouia, Lin, Hong-Yiou, Loh, Horace H., Law, Ping-Yee

“…[Display omitted] The development of tolerance to morphine, one of the most potent analgesics, in the management of chronic pain is a significant clinical…”
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Temporal effect of manipulating NeuroD1 expression with the synthetic small molecule KHS101 on morphine contextual memory by Zhang, Yue, Kibaly, Cherkaouia, Xu, Chi, Loh, Horace H., Law, Ping-Yee

“…The treatment of opioid addiction is challenging because addicts are highly prone to relapse when the memory of the former drug experience is triggered by…”
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Effects of inflammatory pain on CB1 receptor in the midbrain periaqueductal gray by Wilson-Poe, Adrianne R., Wiese, Beth, Kibaly, Cherkaouia, Lueptow, Lindsay, Garcia, Jeniffer, Anand, Preeti, Cahill, Catherine, Morón, Jose A.

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Src-dependent phosphorylation of μ-opioid receptor at Tyr 336 modulates opiate withdrawal by Zhang, Lei, Kibaly, Cherkaouia, Wang, Yu-Jun, Xu, Chi, Song, Kyu Young, McGarrah, Patrick W, Loh, Horace H, Liu, Jing-Gen, Law, Ping-Yee

“…Opiate withdrawal/negative reinforcement has been implicated as one of the mechanisms for the progression from impulsive to compulsive drug use. Increase in…”
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Assessment of neuroactive steroid formation in diabetic rat spinal cord using high-performance liquid chromatography and continuous flow scintillation detection by Mensah-Nyagan, Ayikoe Guy, Saredi, Simona, Schaeffer, Veronique, Kibaly, Cherkaouia, Meyer, Laurence, Melcangi, Roberto Cosimo, Patte-Mensah, Christine

“…The combination of pulse-chase experiments with high-performance liquid chromatography and continuous flow scintillation detection was used successfully to…”
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Regulatory effect of dehydroepiandrosterone on spinal cord nociceptive function by Patte-Mensah, Christine, Meyer, Laurence, Kibaly, Cherkaouia, Mensah-Nyagan, Ayikoe G

“…To characterize endogenous molecules regulating nociception, various groups have focused on dehydroepiandrosterone (DHEA). Indeed, DHEA modulates NMDA and P2X…”
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Assessment of neuroactive steroid formation in diabetic rat spinal cord using high-performance liquid chromatography and continuous flow scintillation detection : Neurosteroids by MENSAH-NYAGAN, Ayikoe Guy, SAREDI, Simona, SCHAEFFER, Veronique, KIBALY, Cherkaouia, MEYER, Laurence, COSIMO MELCANGI, Roberto, PATTE-MENSAH, Christine

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