Search Results - "Kiaei, Dorsa Sadat"
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Development of a semi-automatic segmentation technique based on mean magnetic resonance imaging intensity thresholding for volumetric quantification of plexiform neurofibromas
Published in Heliyon (15-01-2024)“…Plexiform neurofibromas (PNs) are peripheral nerve tumors that occur in 25–50 % of patients with neurofibromatosis type 1. PNs may have complex, diffused, and…”
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A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway
Published in Journal of clinical oncology (01-06-2022)“…2042 Background: Pediatric low-grade gliomas (PLGG) are the most frequent brain tumors in children and the majority of PLGG have activation of the MAPK/ERK…”
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Impact of trametinib on the neuropsychological profile of NF1 patients
Published in Journal of neuro-oncology (01-05-2024)“…Purpose The use of trametinib in the treatment of pediatric low-grade gliomas (PLGG) and plexiform neurofibroma (PN) is being investigated in an ongoing…”
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NFB-08. TRAM-01: A Phase 2 study of trametinib for pediatric patients with neurofibromatosis type 1 and plexiform neurofibromas
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…BACKGROUND: Plexiform neurofibromas (PN) are found in up to 50% of patients with neurofibromatosis type 1 (NF1). Trametinib has been used widely to treat PN…”
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