Search Results - "Ki Cheol Park"
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An Orally Administered Multitarget Tyrosine Kinase Inhibitor, SU11248, Is a Novel Potent Inhibitor of Thyroid Oncogenic RET/Papillary Thyroid Cancer Kinases
Published in The journal of clinical endocrinology and metabolism (01-10-2006)“…Context: The oncogenic RET/PTC tyrosine kinase causes papillary thyroid cancer (PTC). The use of inhibitors specific for RET/PTC may be useful for targeted…”
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2
Let-7 microRNA inhibits the proliferation of human glioblastoma cells
Published in Journal of neuro-oncology (01-03-2011)“…MicroRNAs (miRNAs) are small noncoding RNAs comprising 21–23 nucleotides that regulate gene expression by transcriptionally repressing their complementary…”
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3
The relationship between miRNA-26b and connective tissue growth factor in rat models of aortic banding and debanding
Published in The Korean journal of internal medicine (31-05-2021)“…Background/Aims: Connective tissue growth factor (CTGF) is a profibrotic factor implicated in pressure overload-mediated myocardial fibrosis. In this study, we…”
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4
Dysregulated Expression Profiles of MicroRNAs of Experimentally Induced Cerebral Aneurysms in Rats
Published in Journal of Korean Neurosurgical Society (01-02-2013)“…Cerebral aneurysm (CA) is an important acquired cerebrovascular disease that can cause catastrophic results. MicroRNAs (miRNAs) are small non-coding RNAs,…”
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Environmental and economic loss analyses of the oil discharge from shipwreck for salvage planning
Published in Marine pollution bulletin (01-06-2020)“…In this study, we carry out environmental and economic loss analyses of the oil discharge from the shipwreck Jeh Hun. By performing 500 simulations of…”
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6
Efficacy of robot arm-assisted endoscopic submucosal dissection in live porcine stomach (with video)
Published in Scientific reports (29-07-2024)“…Endoscopic submucosal dissection (ESD) is technically challenging and requires a high level of skill. However, there is no effective method of exposing the…”
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Orphan Nuclear Receptor Small Heterodimer Partner Represses Hepatocyte Nuclear Factor 3/Foxa Transactivation via Inhibition of Its DNA Binding
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2004)“…Small heterodimer partner (SHP; NR0B2) is an atypical orphan nuclear receptor and acts as a coregulator of various nuclear receptors. Herein, we examined a…”
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8
Loss of primary cilia promotes mitochondria-dependent apoptosis in thyroid cancer
Published in Scientific reports (18-02-2021)“…The primary cilium is well-preserved in human differentiated thyroid cancers such as papillary and follicular carcinoma. Specific thyroid cancers such as…”
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9
Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer
Published in Oncogene (09-08-2018)“…Primary cilia are microtubule-based, dynamic organelles characterized by continuous assembly and disassembly. The intraflagellar transport (IFT) machinery,…”
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10
Orphan Nuclear Receptor Small Heterodimer Partner, a Novel Corepressor for a Basic Helix-Loop-Helix Transcription Factor BETA2/NeuroD
Published in Molecular endocrinology (Baltimore, Md.) (01-04-2004)“…Small heterodimer partner (SHP; NR0B2) is an atypical orphan nuclear receptor that lacks a conventional DNA binding domain (DBD) and represses the…”
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Antimicrobial Peptide, Lumbricusin, Ameliorates Motor Dysfunction and Dopaminergic Neurodegeneration in a Mouse Model of Parkinson`s Disease
Published in Journal of microbiology and biotechnology (31-10-2015)“…We recently reported that the antimicrobial peptide Lumbricusin (NH2-RNRRWCIDQQA), isolated from the earthworm, increases cell proliferation in neuroblastoma…”
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12
Differential Role of the Loop Region between Helices H6 and H7 within the Orphan Nuclear Receptors Small Heterodimer Partner and DAX-1
Published in Molecular endocrinology (Baltimore, Md.) (01-05-2004)“…The orphan nuclear receptors small heterodimer partner (SHP) and dosage-sensitive sex-reversal adrenal hypoplasia congenital (AHC) critical region on the X…”
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13
The relationship between miRNA-26b and connective tissue growth factor in rat models of aortic banding and debanding
Published in The Korean journal of internal medicine (01-05-2021)“…Connective tissue growth factor (CTGF) is a profibrotic factor implicated in pressure overload-mediated myocardial fibrosis. In this study, we determined the…”
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Journal Article -
14
Regeneration of thyroid follicles from primordial cells in a murine thyroidectomized model
Published in Laboratory investigation (01-04-2017)“…The functional unit of the thyroid gland, the thyroid follicle, dynamically responds to various stimuli to maintain thyroid hormone homeostasis. However,…”
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15
Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice
Published in PLoS genetics (01-03-2013)“…Impaired mitochondrial oxidative phosphorylation (OXPHOS) has been proposed as an etiological mechanism underlying insulin resistance. However, the initiating…”
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16
Predictive and prognostic roles of electrical cardiometry in noninvasive assessments of community-acquired pneumonia patients with dyspnoea
Published in Hong Kong journal of emergency medicine (01-07-2021)“…Background: Thoracic impedance monitoring able to detect pneumonia in the very early phase of emerging infiltration prior the patient developed remarkable…”
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The physical properties of Al-doped zinc oxide films prepared by RF magnetron sputtering
Published in Thin solid films (01-08-1997)“…Al-doped zinc oxide (AZO) films are prepared by RF magnetron sputtering on glass and Si substrates with specifically designed ZnO targets containing different…”
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18
The Atypical Orphan Nuclear Receptor DAX-1 Interacts with Orphan Nuclear Receptor Nur77 and Represses Its Transactivation
Published in Molecular endocrinology (Baltimore, Md.) (01-08-2004)“…DAX-1 (dosage-sensitive sex reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1) (NROB1) is an atypical member of the nuclear…”
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19
Orphan nuclear receptor SHP interacts with and represses hepatocyte nuclear factor-6 (HNF-6) transactivation
Published in Biochemical journal (01-08-2008)“…SHP (small heterodimer partner; NR0B2) is an atypical orphan NR (nuclear receptor) that functions as a transcriptional co-repressor by interacting with a…”
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Tumor Suppressor LKB1 Inhibits Activation of Signal Transducer and Activator of Transcription 3 (STAT3) by Thyroid Oncogenic Tyrosine Kinase Rearranged in Transformation (RET)/Papillary Thyroid Carcinoma (PTC)
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2007)“…The tumor suppressor LKB1 (STK11) is a cytoplasmic/nuclear serine/threonine kinase, defects in which cause Peutz-Jeghers syndrome (PJS) in humans and animals…”
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