Search Results - "Ki, Kim H"

Increased nicotinamide adenine dinucleotide pool promotes colon cancer progression by suppressing reactive oxygen species level by Hong, Sun M., Hwang, Sung W., Wang, Taejun, Park, Chang W., Ryu, Yeon‐Mi, Jung, Jin‐Hak, Shin, Ji H., Kim, Sang‐Yeob, Lee, Jong L., Kim, Chan W., Yoon, Gyesoon, Kim, Ki H., Myung, Seung‐Jae, Choi, Kwan Y.

“…Nicotinamide adenine dinucleotide (NAD) exists in an oxidized form (NAD+) and a reduced form (NADH). NAD+ plays crucial roles in cancer metabolism, including…”
Get full text

Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes by Xu, Hao, Majmudar, Jaimeen D, Davda, Dahvid, Ghanakota, Phani, Kim, Ki H, Carlson, Heather A, Showalter, Hollis D, Martin, Brent R, Amidon, Gordon L

“…Understanding the mechanistic basis of prodrug delivery and activation is critical for establishing species-specific prodrug sensitivities necessary for…”
Get full text

Precise T cell recognition programs designed by transcriptionally linking multiple receptors by Williams, Jasper Z, Allen, Greg M, Shah, Devan, Sterin, Igal S, Kim, Ki H, Garcia, Vivian P, Shavey, Gavin E, Yu, Wei, Puig-Saus, Cristina, Tsoi, Jennifer, Ribas, Antoni, Roybal, Kole T, Lim, Wendell A

“…Living cells often identify their correct partner or target cells by integrating information from multiple receptors, achieving levels of recognition that are…”
Get full text

Programming multicellular assembly with synthetic cell adhesion molecules by Stevens, Adam J., Harris, Andrew R., Gerdts, Josiah, Kim, Ki H., Trentesaux, Coralie, Ramirez, Jonathan T., McKeithan, Wesley L., Fattahi, Faranak, Klein, Ophir D., Fletcher, Daniel A., Lim, Wendell A.

“…Cell adhesion molecules are ubiquitous in multicellular organisms, specifying precise cell–cell interactions in processes as diverse as tissue development,…”
Get full text

Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death by Jeong, Ji C, Shin, Won Y, Kim, Thae H, Kwon, Chae H, Kim, Jae H, Kim, Yong K, Kim, Ki H

“…Silibinin, a natural polyphenolic flavonoid, has been reported to induce cell death in various cancer cell types. However, the molecular mechanism is not…”
Get full text

Effects of Teriparatide and Vibration on Bone Mass and Bone Strength in People with Bone Loss and Spinal Cord Injury: A Randomized, Controlled Trial by Edwards, W Brent, Simonian, Narina, Haider, Ifaz T, Anschel, Alan S, Chen, David, Gordon, Keith E, Gregory, Elaine K, Kim, Ki H, Parachuri, Ramadevi, Troy, Karen L, Schnitzer, Thomas J

“…ABSTRACT Spinal cord injury (SCI) is associated with marked bone loss and an increased risk of fracture. We randomized 61 individuals with chronic SCI and low…”
Get full text

Modification of metal surfaces by microwave plasma at atmospheric pressure by Shin, Dong H., Bang, Chan U., Kim, Jong H., Han, Kun H., Hong, Yong C., Uhm, Han S., Park, Dae K., Kim, Ki H.

“…Continuous wave (CW) microwave discharges operated at atmospheric pressure in argon gas were applied to surface modification of metal surfaces for improvement…”
Get full text

Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent by Li, Qun, Woods, Keith W., Claiborne, Akiyo, Gwaltney, II, Stephen L., Barr, Kenneth J., Liu, Gang, Gehrke, Laura, Credo, R.Bruce, Hui, Yu Hua, Lee, Jang, Warner, Robert B., Kovar, Peter, Nukkala, Michael A., Zielinski, Nicolette A., Tahir, Stephen K., Fitzgerald, Michael, Kim, Ki H., Marsh, Kennan, Frost, David, Ng, Shi-Chung, Rosenberg, Saul, Sham, Hing L.

“…A series of indole containing oxazolines has been discovered as a result of structural modifications of the lead compound A-105972. The compounds exert their…”
Get full text

Predictive Value of Diaphragm Muscle Ultrasound for Ventilator Weaning Outcomes After Cervical Spinal Cord Injury: A Retrospective Case Series by Bhatia, Natasha S, Kunzweiler, Stephany, Conley, Christopher, Kim, Ki H, Adewuyi, Adenike A, Mondriguez-Gonzalez, Antonio, Wolfe, Lisa F, Kwasny, Mary, Franz, Colin K

“…Neuromuscular respiratory failure after cervical spinal cord injury (cSCI) can lead to dependence on an invasive mechanical ventilator. Ventilator-free…”
Get full text

Association Between Vascular Calcification Scores on Plain Radiographs and Fatty Acid Contents of Erythrocyte Membrane in Hemodialysis Patients by Son, Young K., MD, Lee, Su M., MD, Kim, Seong E., MD, Kim, Ki H., MD, Lee, Seon Y., BS, Bae, Hae R., MD, Han, Jin Y., MD, Park, Yongsoon, PhD, An, Won S., MD

“…Objective Vascular calcification (VC) scores determined by using simple plain radiographic films are known to be associated with coronary artery disease and…”
Get full text

Morphological features of mucous secretory organ and mucous secretion of loach Misgurnus anguillicaudatus skin for friction drag reduction by Seo, Eunseok, Yoon, Gun‐Young, Kim, Hae‐Nyeok, Lim, Jae H., Kim, Seonghan, Kim, Bumju, Kim, Ki H., Lee, Sang J.

“…We examined the functional morphology of loach Misgurnus anguillicaudatus skin by using synchrotron X‐ray micro‐computed tomography (SR‐μCT) and high‐contrast…”
Get full text

Unilateral cutaneous mycotic septic vasculitis in a patient with Aspergillus vegetation in the ascending aorta by PARK, Jeong Y., SHIN, Dong H., CHOI, Jong S., KIM, Ki H., BAE, Young K.

Get full text

Low-Temperature-Grown Transition Metal Oxide Based Storage Materials and Oxide Transistors for High-Density Non-volatile Memory by Lee, Myoung-Jae, Kim, Sun I., Lee, Chang B., Yin, Huaxiang, Ahn, Seung-Eon, Kang, Bo S., Kim, Ki H., Park, Jae C., Kim, Chang J., Song, Ihun, Kim, Sang W., Stefanovich, Genrikh, Lee, Jung H., Chung, Seok J., Kim, Yeon H., Park, Youngsoo

“…An effective stacked memory concept utilizing all‐oxide‐based device components for future high‐density nonvolatile stacked structure data storage is…”
Get full text

From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells by Gaisina, Irina N, Gallier, Franck, Ougolkov, Andrei V, Kim, Ki H, Kurome, Toru, Guo, Songpo, Holzle, Denise, Luchini, Doris N, Blond, Sylvie Y, Billadeau, Daniel D, Kozikowski, Alan P

“…Recent studies have demonstrated that glycogen synthase kinase 3β (GSK-3β) is overexpressed in human colon and pancreatic carcinomas, contributing to cancer…”
Get full text

Gene structure and differential modulation of multiple rockbream ( Oplegnathus fasciatus) hepcidin isoforms resulting from different biological stimulations by Cho, Young S., Lee, Sang Y., Kim, Ki H., Kim, Sung K., Kim, Dong S., Nam, Yoon K.

“…Hepcidin, an antimicrobial and iron-regulating peptide, is a key molecule of the innate immune system of bony fish. In this study, four isoforms of hepcidin…”
Get full text

Discovery and Optimization of Anthranilic Acid Sulfonamides as Inhibitors of Methionine Aminopeptidase-2:  A Structural Basis for the Reduction of Albumin Binding by Sheppard, George S, Wang, Jieyi, Kawai, Megumi, Fidanze, Steve D, BaMaung, Nwe Y, Erickson, Scott A, Barnes, David M, Tedrow, Jason S, Kolaczkowski, Lawrence, Vasudevan, Anil, Park, David C, Wang, Gary T, Sanders, William J, Mantei, Robert A, Palazzo, Fabio, Tucker-Garcia, Lora, Lou, Pingping, Zhang, Qian, Park, Chang H, Kim, Ki H, Petros, Andrew, Olejniczak, Edward, Nettesheim, David, Hajduk, Phillip, Henkin, Jack, Lesniewski, Richard, Davidsen, Steven K, Bell, Randy L

“…Methionine aminopeptidase-2 (MetAP2) is a novel target for cancer therapy. As part of an effort to discover orally active reversible inhibitors of MetAP2, a…”
Get full text

Mechanistic interpretation of the genotoxicity of nitrofurans (antibacterial agents) using quantitative structure-activity relationships and comparative molecular field analysis by Debnath, Asim Kumar, Hansch, Corwin, Kim, Ki H, Martin, Yvonne C

“…Quantitative structure-activity relationship (QSAR) and comparative molecular field analysis (CoMFA) have been applied to elucidate the mechanisms of…”
Get full text

Poster 513 Videogame-Induced Ulnar and Median Nerve Neuropathy in a Patient With Spinal Cord Injury: A Case Report by Amorapanth, Prin, Kim, Ki H.

Get full text

Synthesis and structure–activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors by Ouyang, Xiaohu, Chen, Xiaoling, Piatnitski, Evgueni L., Kiselyov, Alexander S., He, Hai-Ying, Mao, Yunyu, Pattaropong, Vatee, Yu, Yang, Kim, Ki H., Kincaid, John, Smith, Leon, Wong, Wai C., Lee, Sui Ping, Milligan, Daniel L., Malikzay, Asra, Fleming, James, Gerlak, Jason, Deevi, Dhanvanthri, Doody, Jacqueline F., Chiang, Hui-Hsien, Patel, Sheetal N., Wang, Ying, Rolser, Robin L., Kussie, Paul, Labelle, Marc, Tuma, M. Carolina

“…The synthesis and SAR studies on triazole-containing tubulin inhibitor class are reported. A novel triazole-containing chemical series was shown to inhibit…”
Get full text

Triphendiol (NV-196), development of a novel therapy for pancreatic cancer by Wang, Xiaohong, McKernan, Robert, Kim, Ki H, Alvero, Ayesha B, Whiting, Ainslie, Thompson, John Anthony, Mor, Gil, Saif, Muhammad Wasif, Husband, Alan J, Brown, David M, Tytler, Ewan Milne

“…Despite incremental progress in the treatment of pancreatic adenocarcinoma, the prognosis of patients remains poor. Here, we report the preclinical studies in…”
Get full text