Search Results - "Khyrul, Wara A.K.M."
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Deficiency of lncRNA SNHG12 impairs ischemic limb neovascularization by altering an endothelial cell cycle pathway
Published in JCI insight (11-01-2022)“…SNHG12, a long noncoding RNA (lncRNA) dysregulated in atherosclerosis, is known to be a key regulator of vascular senescence in endothelial cells (ECs)…”
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Gene expression in endothelial cells and intimal smooth muscle cells in atherosclerosis-prone or atherosclerosis-resistant regions of the human aorta
Published in Journal of vascular research (01-01-2008)“…We compared the atherogenic gene expression in the intimas of atherosclerosis-prone regions (proximal walls), which are exposed to disturbed shear stress, and…”
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Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence
Published in Science translational medicine (19-02-2020)“…Long noncoding RNAs (lncRNAs) are emerging regulators of biological processes in the vessel wall; however, their role in atherosclerosis remains poorly…”
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A Smooth Muscle Cell–Enriched Long Noncoding RNA Regulates Cell Plasticity and Atherosclerosis by Interacting With Serum Response Factor
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2021)“…Vascular smooth muscle cell (VSMC) plasticity plays a critical role in the development of atherosclerosis. Long noncoding RNAs (lncRNAs) are emerging as…”
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Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2021)“…[Figure: see text]…”
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The Integrin-linked Kinase Regulates Cell Morphology and Motility in a Rho-associated Kinase-dependent Manner
Published in The Journal of biological chemistry (24-12-2004)“…The integrin-linked kinase (ILK) is a multidomain focal adhesion protein implicated in signal transmission from integrin and growth factor receptors. We have…”
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Abstract 14679: LncRNA SNHG12 Regulates Vascular Senescence and Atherosclerosis by Targeting A DNA-PK-Mediated DNA Damage Response
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionNon-coding RNAs have garnered widespread attention as emerging regulators of diverse biological processes. Herein, we identify and validate a…”
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