Search Results - "Khutornaya, Maria"

Atorvastatin Can Modulate DNA Damage Repair in Endothelial Cells Exposed to Mitomycin C by Sinitsky, Maxim, Asanov, Maxim, Sinitskaya, Anna, Shishkova, Daria, Khutornaya, Maria, Minina, Varvara, Ponasenko, Anastasia

“…HMG-CoA reductase inhibitors (statins) are widely used in the therapy of atherosclerosis and have a number of pleiotropic effects, including DNA repair…”
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TREM-1 as a Marker of Multiple Organ Failure in Cardiac Surgery by Khutornaya, Maria V., Sinitsky, Maxim Yu, Sinitskaya, Anna V., Asanov, Maxim А., Ponasenko, Anastasia V., Grigoriev, Evgeny V.

“…Systemic inflammatory response syndrome (SIRS) frequently accompanies early postoperative period after cardiac surgery and in some cases is complicated by…”
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IL18-family Genes Polymorphism Is Associated with the Risk of Myocardial Infarction and IL18 Concentration in Patients with Coronary Artery Disease by Ponasenko, Anastasia V., Tsepokina, Anna V., Khutornaya, Maria V., Sinitsky, Maxim Yu, Barbarash, Olga L.

“…Atherogenesis is mainly determined by endothelial dysfunction, lipid metabolism disorders and inflammation. The atherogenesis-related inflammatory process is a…”
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The Role of Polymorphism in the Endothelial Homeostasis and Vitamin D Metabolism Genes in the Severity of Coronary Artery Disease by Ponasenko, Anastasia, Sinitskaya, Anna, Sinitsky, Maxim, Khutornaya, Maria, Barbarash, Olga

“…Coronary artery disease (CAD) remains one of the leading causes of cardiovascular morbidity and mortality worldwide. The maintenance of endothelial homeostasis…”
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Association of TLR and TREM-1 gene polymorphisms with risk of coronary artery disease in a Russian population by Golovkin, Alexey S., Ponasenko, Anastasia V., Khutornaya, Maria V., Kutikhin, Anton G., Salakhov, Ramil R., Yuzhalin, Arseniy E., Zhidkova, Irina I., Barbarash, Olga L., Barbarash, Leonid S.

“…Atherosclerosis, manifesting itself as acute coronary syndrome, stroke, and peripheral arterial diseases, is a chronic progressive inflammatory disease which…”
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A Genomics-Based Model for Prediction of Severe Bioprosthetic Mitral Valve Calcification by Ponasenko, Anastasia V, Khutornaya, Maria V, Kutikhin, Anton G, Rutkovskaya, Natalia V, Tsepokina, Anna V, Kondyukova, Natalia V, Yuzhalin, Arseniy E, Barbarash, Leonid S

“…Severe bioprosthetic mitral valve calcification is a significant problem in cardiovascular surgery. Unfortunately, clinical markers did not demonstrate…”
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Identification of Key Genes and Pathways in Genotoxic Stress Induced Endothelial Dysfunction: Results of Whole Transcriptome Sequencing by Sinitsky, Maxim, Sinitskaya, Anna, Shishkova, Daria, Tupikin, Alexey, Asanov, Maxim, Khutornaya, Maria, Kabilov, Marsel, Ponasenko, Anastasia

“…Atherosclerosis is a leading cause of cardiovascular morbidity and mortality worldwide. Endothelial disfunction underlying the atherogenesis can be triggered…”
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An association between single nucleotide polymorphisms within TLR and TREM-1 genes and infective endocarditis by Golovkin, Alexey S., Ponasenko, Anastasia V., Yuzhalin, Arseniy E., Salakhov, Ramil R., Khutornaya, Maria V., Kutikhin, Anton G., Rutkovskaya, Natalia V., Savostyanova, Yulia Yu, Barbarash, Leonid S.

“…•Immune response gene polymorphisms may be associated with risk of various diseases.•TLR and TREM-1 gene polymorphisms may be associated with IE risk.•TLR6…”
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Inherited Variation in Cytokine, Acute Phase Response, and Calcium Metabolism Genes Affects Susceptibility to Infective Endocarditis by Yuzhalin, Arseniy E., Barbarash, Leonid S., Kazachek, Yana V., Odarenko, Yuri N., Kondyukova, Natalia V., Rutkovskaya, Natalia V., Khutornaya, Maria V., Kutikhin, Anton G., Ponasenko, Anastasia V., Tsepokina, Anna V.

“…Infective endocarditis (IE) is a septic inflammation of the endocardium. Recognition of microbial patterns, cytokine and acute phase responses, hemostasis…”
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TREM1 AS AN IMPORTANT PARTICIPANT IN THE DEVELOPMENT OF CRITICAL COMPLICATIONS IN HEART SURGERY PATIENTS by Khutornaya, Maria Vladimirovna, Ponasenko, Anastasia Valerievna, Grigoriev, E V

“…Introduction: It is known that the variability of immune response genes and the corresponding immune profile modulate the risk of a number of pathologies…”
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Association of TLR and TREM-1 gene polymorphisms with atherosclerosis severity in a Russian population by Kutikhin, Anton G., Ponasenko, Anastasia V., Khutornaya, Maria V., Yuzhalin, Arseniy E., Zhidkova, Irina I., Salakhov, Ramil R., Golovkin, Alexey S., Barbarash, Olga L., Barbarash, Leonid S.

“…Local vascular immune response is primarily initiated via Toll-like receptors (TLRs) and triggering receptor expressed on myeloid cells-1 (TREM-1). We…”
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REGULATION OF THE SYSTEMIC INFLAMMATORY RESPONSE IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS by Ponasenko, Anastasia Valerievna, Khutornaya, Maria Vladimirovna, Sinitskaya, Anna Victorovna, Barbarash, Olga Leonidovna

“…Introduction. Data on the role of inflammation in the progression and manifestation of multifocal atherosclerosis (MFA) are contradictory. The systemic process…”
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EVALUATION OF THE LOCAL PROFILE OF CYTOKINES EXPRESSED BY NATIVE HEART VALVES OBTAINED FROM PATIENTS WITH ACQUIRED HEART DEFECTS by Sinitskaya, Anna Victorovna, Sinitsky, Maksim Yurievich, Khutornaya, Maria Vladimirovna, Ponasenko, Anastasia Valerievna

“…Doing. The pathogenesis of acquired heart defects is a complex process involving many different factors. One of the triggers for the development of…”
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VARIABILITY OF THE GENES OF NATRIURETIC PEPTIDES AND ANTIOXIDANT PROTECTION IN PATIENTS WITH MYOCARDIAL INFARCTION by Khryachkova, O. N., Khutornaya, Maria V., Sinitskaya, A. V., Poddubnyak, Alyona O, Ponasenko, A V

“…Introduction. Cardiovascular diseases (CVD) continue to be the subject of scientific research in relation to molecular genetic predictors of their development…”
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CIRCULATION MICRORNA AS A POSSIBLE PREDICTOR OF ANTHRACYCLINE-INDUCED CARDIOTOXICITY by Khutornaya, Maria Vladimirovna, Sinitskaya, Anna Victorovna, Shcheglova, Anna Victorovna, Sumin, Alexei Nikolaevich, Ponasenko, Anastasia Valerievna

“…Introduction. Doxorubicin is an anthracycline antibiotic widely used in the treatment of malignant neoplasms. Anthracyclines have been shown to have an…”
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Inflammatory Response Genes' Polymorphism Associated with Risk of Rheumatic Heart Disease by Sinitskaya, Anna, Khutornaya, Maria, Hryachkova, Oksana, Asanov, Maxim, Poddubnyak, Alyona, Ponasenko, Anastasia, Sinitsky, Maxim

“…Rheumatic heart disease (RHD) caused by group A streptococcus infection is one of the most important reasons of cardiovascular morbidity and mortality in low-…”
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Immune Response and Lipid Metabolism Gene Polymorphisms Are Associated with the Risk of Obesity in Middle-Aged and Elderly Patients by Ponasenko, Anastasia, Sinitsky, Maxim, Minina, Varvara, Vesnina, Anna, Khutornaya, Maria, Prosekov, Alexander, Barbarash, Olga

“…More than two billion people around the world are overweight or obese. Even in apparently healthy people, obesity has a potent effect on their quality of life…”
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Role of the genes of the natriuretic peptide and antioxidant defense systems in creating the risk of myocardial infarction development (the preliminary results of a pilot study) by Khutornaya, M.V., Khryachkova, O.N., Sinitskaya, A.V., Poddubnya, A.O., Ponasenko, A.V., Kashtalap, V.V.

“…Aim: to reveal a relationship of single-nucleotide polymorphic variants of the genes of the natriuretic peptides, antioxidant defense systems and the…”
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Genetic Markers of Systemic Inflammatory Response in Cardiac Surgery (Review) by Ponasenko, A. V., Sinitsky, M. Yu, Khutornaya, M. V., Barabash, O. L.

“…The systemic inflammatory response syndrome is a typical systemic reaction to tissue injury and an important factor for structural and functional regeneration…”
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