Search Results - "Khuong, Thang"

Sucralose Promotes Food Intake through NPY and a Neuronal Fasting Response by Wang, Qiao-Ping, Lin, Yong Qi, Zhang, Lei, Wilson, Yana A., Oyston, Lisa J., Cotterell, James, Qi, Yue, Khuong, Thang M., Bakhshi, Noman, Planchenault, Yoann, Browman, Duncan T., Lau, Man Tat, Cole, Tiffany A., Wong, Adam C.N., Simpson, Stephen J., Cole, Adam R., Penninger, Josef M., Herzog, Herbert, Neely, G. Gregory

“…Non-nutritive sweeteners like sucralose are consumed by billions of people. While animal and human studies have demonstrated a link between synthetic sweetener…”
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Peripheral straightjacket (α2δ Ca 2+ channel subunit) expression is required for neuropathic sensitization in Drosophila by Khuong, Thang M, Hamoudi, Zina, Manion, John, Loo, Lipin, Muralidharan, Arjun, Neely, G Gregory

“…Nerve injury leads to devastating and often untreatable neuropathic pain. While acute noxious sensation (nociception) is a crucial survival mechanism and is…”
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Synaptic PI(3,4,5)P3 Is Required for Syntaxin1A Clustering and Neurotransmitter Release by Khuong, Thang Manh, Habets, Ron L.P., Kuenen, Sabine, Witkowska, Agata, Kasprowicz, Jaroslaw, Swerts, Jef, Jahn, Reinhard, van den Bogaart, Geert, Verstreken, Patrik

“…PI(3,4,5)P3 is a low-abundance lipid thought to play a role in the regulation of synaptic activity; however, the mechanism remains obscure. We have constructed…”
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Molecular dissection of box jellyfish venom cytotoxicity highlights an effective venom antidote by Lau, Man-Tat, Manion, John, Littleboy, Jamie B., Oyston, Lisa, Khuong, Thang M., Wang, Qiao-Ping, Nguyen, David T., Hesselson, Daniel, Seymour, Jamie E., Neely, G. Gregory

“…The box jellyfish Chironex fleckeri is extremely venomous, and envenoming causes tissue necrosis, extreme pain and death within minutes after severe exposure…”
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Systematic functional identification of cancer multi-drug resistance genes by Lau, Man-Tat, Ghazanfar, Shila, Parkin, Ashleigh, Chou, Angela, Rouaen, Jourdin R, Littleboy, Jamie B, Nessem, Danielle, Khuong, Thang M, Nevoltris, Damien, Schofield, Peter, Langley, David, Christ, Daniel, Yang, Jean, Pajic, Marina, Neely, G Gregory

“…Drug resistance is a major obstacle in cancer therapy. To elucidate the genetic factors that regulate sensitivity to anti-cancer drugs, we performed…”
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Epiregulin and EGFR interactions are involved in pain processing by Martin, Loren J, Smith, Shad B, Khoutorsky, Arkady, Magnussen, Claire A, Samoshkin, Alexander, Sorge, Robert E, Cho, Chulmin, Yosefpour, Noosha, Sivaselvachandran, Sivaani, Tohyama, Sarasa, Cole, Tiffany, Khuong, Thang M, Mir, Ellen, Gibson, Dustin G, Wieskopf, Jeffrey S, Sotocinal, Susana G, Austin, Jean Sebastien, Meloto, Carolina B, Gitt, Joseph H, Gkogkas, Christos, Sonenberg, Nahum, Greenspan, Joel D, Fillingim, Roger B, Ohrbach, Richard, Slade, Gary D, Knott, Charles, Dubner, Ronald, Nackley, Andrea G, Ribeiro-da-Silva, Alfredo, Neely, G Gregory, Maixner, William, Zaykin, Dmitri V, Mogil, Jeffrey S, Diatchenko, Luda

“…The EGFR belongs to the well-studied ErbB family of receptor tyrosine kinases. EGFR is activated by numerous endogenous ligands that promote cellular growth,…”
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Nerve injury drives a heightened state of vigilance and neuropathic sensitization in Drosophila by Khuong, Thang M, Wang, Qiao-Ping, Manion, John, Oyston, Lisa J, Lau, Man-Tat, Towler, Harry, Lin, Yong Qi, Neely, G Gregory

“…Injury can lead to devastating and often untreatable chronic pain. While acute pain perception (nociception) evolved more than 500 million years ago, virtually…”
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Conserved systems and functional genomic assessment of nociception by Khuong, Thang M, Neely, Graham Greg

“…Chronic pain represents a significant public health concern and current therapies do not adequately meet patient needs. With the advent of genomic…”
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PGC1α Controls Sucrose Taste Sensitization in Drosophila by Wang, Qiao-Ping, Lin, Yong Qi, Lai, Mei-Ling, Su, Zhiduan, Oyston, Lisa J., Clark, Teleri, Park, Scarlet J., Khuong, Thang M., Lau, Man-Tat, Shenton, Victoria, Shi, Yan-Chuan, James, David E., Ja, William W., Herzog, Herbert, Simpson, Stephen J., Neely, G. Gregory

“…Perceived palatability of food controls caloric intake. Sweet taste is the primary means of detecting the carbohydrate content of food. Surprisingly, sweet…”
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A simple high throughput assay to evaluate water consumption in the fruit fly by Lau, Man-Tat, Lin, Yong Qi, Kisling, Stefan, Cotterell, James, Wilson, Yana A., Wang, Qiao-Ping, Khuong, Thang M., Bakhshi, Noman, Cole, Tiffany A., Oyston, Lisa J., Cole, Adam R., Neely, G. Gregory

“…Water intake is essential for survival and thus under strong regulation. Here, we describe a simple high throughput system to monitor water intake over time in…”
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Neuronal Lamin regulates motor circuit integrity and controls motor function and lifespan by Oyston, Lisa J, Lin, Yong Qi, Khuong, Thang M, Wang, Qiao-Ping, Lau, Man Tat, Clark, Teleri, Neely, G Gregory

“…Neuronal aging involves a progressive decline in cognitive abilities and loss of motor function. Mutations in human genes ( ) lead to a wide-range of diseases…”
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Fruit flies as a powerful model to drive or validate pain genomics efforts by Leung, Calvin, Wilson, Yana, Khuong, Thang M, Neely, G Gregory

“…Chronic pain is a disabling condition that persists even after normal healing processes are complete and presents considerable physical, psychological and…”
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CAMELLIA HOAANA (THEACEAE, SECTION CORALLINA), A NEW SPECIES FROM BU GIA MAP NATIONAL PARK IN SOUTHERN VIETNAM by Yang, Shi-Xiong, Kieu, Dinh Thap, Le, Trong Hung, Khuong, Huu Thang

“…Camellia hoaana, a new species of the Camellia sect. Corallina (Theaceae) from Bu Gia Map National Park, Vietnam, is described and illustrated. Morphological…”
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WASP is activated by phosphatidylinositol-4,5-bisphosphate to restrict synapse growth in a pathway parallel to bone morphogenetic protein signaling by Khuong, Thang Manh, Habets, Ron L. P., Slabbaert, Jan R., Verstreken, Patrik

“…Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P₂] is a membrane lipid involved in several signaling pathways. However, the role of this lipid in the regulation…”
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Exploring the Therapeutic Potential of Camellia longii Orel & Luu Leaf Extracts for Memory Loss in Alzheimer’s Disease: Novel Findings and Functional Food Applications by Anh Phan, Dao Thi, Tran, Huy Thanh, Le, Hien Phung, Khuong, Thang Huu, Ha, Hue Thi, Nguyen, Dzung Tan, Nguyen, Giang Tien, Le, Minh Van, Ly, Trieu Hai

“…Novel research on the chemical compositions and biochemical activities of Camellia longii Orel and Luu leaf extracts revealed valuable resources with potential…”
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A fruit fly model for studying paclitaxel-induced peripheral neuropathy and hyperalgesia [version 2; peer review: 2 approved, 1 approved with reservations] by Hamoudi, Zina, Khuong, Thang Manh, Cole, Tiffany, Neely, G. Gregory

“…Background: Paclitaxel-induced peripheral neuropathy is a common and limiting side effect of an approved and effective chemotherapeutic agent. The cause of…”
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Phosphoinositides at the Neuromuscular Junction of Drosophila melanogaster: A Genetic Approach by Slabbaert, Jan R., Khuong, Thang Manh, Verstreken, Patrik

“…Phosphoinositides are critically important for numerous cellular signaling pathways such as membrane trafficking, cytoskeleton rearrangement, and ion channel…”
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Vitamin B5 is a context-dependent dietary regulator of nociception by Hamoudi, Zina, Leung, Calvin, Khuong, Thang Manh, Cooney, Gregory, Neely, G Gregory

“…Abstract Chronic pain has an enormous impact on the quality of life of billions of patients, families, and caregivers worldwide. Current therapies do not…”
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Human induced pluripotent stem cell-derived GABAergic interneuron transplants attenuate neuropathic pain by Manion, John, Khuong, Thang, Harney, Dylan, Littleboy, Jamie B., Ruan, Travis, Loo, Lipin, Costigan, Michael, Larance, Mark, Caron, Leslie, Neely, G. Gregory

“…Neuropathic pain causes severe suffering, and most patients are resistant to current therapies. A core element of neuropathic pain is the loss of inhibitory…”
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Peripheral straightjacket (α2δ Ca2+ channel subunit) expression is required for neuropathic sensitization in Drosophila by Khuong, Thang M., Hamoudi, Zina, Manion, John, Loo, Lipin, Muralidharan, Arjun, Neely, G. Gregory

“…Nerve injury leads to devastating and often untreatable neuropathic pain. While acute noxious sensation (nociception) is a crucial survival mechanism and is…”
Get full text