Search Results - "Khramtsov, Pavel"
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Optimizing the Composition of the Substrate Enhances the Performance of Peroxidase-like Nanozymes in Colorimetric Assays: A Case Study of Prussian Blue and 3,3′-Diaminobenzidine
Published in Molecules (Basel, Switzerland) (01-11-2023)“…One of the emerging trends in modern analytical and bioanalytical chemistry involves the substitution of enzyme labels (such as horseradish peroxidase) with…”
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Reaction of Pyrrolobenzothiazines with Schiff Bases and Carbodiimides: Approach to Angular 6/5/5/5-Tetracyclic Spiroheterocycles
Published in Molecules (Basel, Switzerland) (01-05-2024)“…1 -Pyrrole-2,3-diones, fused at [ ]-side with a heterocycle, are suitable platforms for the synthesis of various angular polycyclic alkaloid-like…”
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Nuclear magnetic resonance immunoassay of tetanus antibodies based on the displacement of magnetic nanoparticles
Published in Analytical and bioanalytical chemistry (01-02-2021)“…A nuclear magnetic resonance (NMR) immunoassay based on the application of carbon-coated iron nanoparticles conjugated with recognition molecules was designed…”
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The Effect of PEGylated Graphene Oxide Nanoparticles on the Th17-Polarization of Activated T Helpers
Published in Materials (16-01-2023)“…We investigated the direct effect of PEGylated graphene oxide (P-GO) nanoparticles on the differentiation, viability, and cytokine profile of activated T…”
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Modified Desolvation Method Enables Simple One-Step Synthesis of Gelatin Nanoparticles from Different Gelatin Types with Any Bloom Values
Published in Pharmaceutics (22-09-2021)“…Gelatin nanoparticles found numerous applications in drug delivery, bioimaging, immunotherapy, and vaccine development as well as in biotechnology and food…”
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Vertical Flow Immunoassay Based on Carbon Black Nanoparticles for the Detection of IgG against SARS-CoV-2 Spike Protein in Human Serum: Proof-of-Concept
Published in Biosensors (Basel) (29-08-2023)“…Point-of-care tests play an important role in serological diagnostics of infectious diseases and post-vaccination immunity monitoring, including in COVID-19…”
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Human Chorionic Gonadotropin in the Regulation of T-Helpers Type 17
Published in BIO Web of Conferences (01-01-2023)“…Chorionic gonadotropin (hCG) is a key pregnancy hormone that regulates steroidogenesis and has immunomodulatory activity. We studied the effects of native and…”
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Synthesis and Application of Albumin Nanoparticles Loaded with Prussian Blue Nanozymes
Published in Colloids and interfaces (01-06-2022)“…Prussian blue nanozymes exhibit peroxidase-like catalytic activity and are therefore considered a stable and inexpensive alternative to natural peroxidases in…”
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The effects of human pregnancy-specific β1-glycoprotein preparation on Th17 polarization of CD4+ cells and their cytokine profile
Published in BMC immunology (30-10-2020)“…Abstract Background Pregnancy-specific β1-glycoproteins are capable of regulating innate and adaptive immunity, exerting predominantly suppressive effects. In…”
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Interaction of Graphene Oxide Modified with Linear and Branched PEG with Monocytes Isolated from Human Blood
Published in Nanomaterials (Basel, Switzerland) (30-12-2021)“…Multiple graphene-based therapeutics have recently been developed, however potential risks related to the interaction between nanomaterials and immune cells…”
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Prussian Blue Nanozymes with Enhanced Catalytic Activity: Size Tuning and Application in ELISA-like Immunoassay
Published in Nanomaterials (Basel, Switzerland) (10-05-2022)“…Prussian blue nanozymes possessing peroxidase-like activity gather significant attention as alternatives to natural enzymes in therapy, biosensing, and…”
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Effects of pregnancy-specific β-1-glycoprotein on the helper T-cell response
Published in Archives of biological sciences (2019)“…Pregnancy-specific ?-1-glycoproteins (PSGs) are capable of regulating innate and adaptive immunity. As fetal antigens circulate in the blood of pregnant women,…”
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Magnetic Nanoclusters Coated with Albumin, Casein, and Gelatin: Size Tuning, Relaxivity, Stability, Protein Corona, and Application in Nuclear Magnetic Resonance Immunoassay
Published in Nanomaterials (Basel, Switzerland) (01-09-2019)“…The surface functionalization of magnetic nanoparticles improves their physicochemical properties and applicability in biomedicine. Natural polymers, including…”
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Measuring the concentration of protein nanoparticles synthesized by desolvation method: Comparison of Bradford assay, BCA assay, hydrolysis/UV spectroscopy and gravimetric analysis
Published in International journal of pharmaceutics (15-04-2021)“…[Display omitted] •Desolvation procedure and yield of nanoparticles depends on the source of BSA.•Thermally cross-linked BSA nanoparticles can be used as…”
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Development and performance of NLISA for C-reactive protein detection based on Prussian blue nanoparticle conjugates
Published in Analytical and bioanalytical chemistry (01-05-2024)“…Prussian blue nanoparticles (PBNPs), also called nanozymes, are very attractive as an alternative to horseradish peroxidase in immunoassay development due to…”
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Synthesis of Prussian Blue nanoparticles in water/alcohol mixtures
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (05-04-2024)“…Prussian Blue, a blue coordination polymer has a very promising future in the realm of biomedicine. Its nanoparticles, known as catalytic labels or nanozymes…”
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Solid-phase nuclear magnetic resonance immunoassay for the prostate-specific antigen by using protein-coated magnetic nanoparticles
Published in Mikrochimica acta (1966) (01-12-2019)“…A solid phase NMR-based sandwich immunoassay for the prostate-specific antigen (PSA) is presented. Carbon-encapsulated iron nanoparticles were functionalized…”
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Highly Stable Conjugates of Carbon Nanoparticles with DNA Aptamers
Published in Langmuir (04-09-2018)“…Conjugates of carbon nanoparticles and aptamers have great potential in many areas of biomedicine. In order to be implemented in practice, such conjugates…”
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Dot immunoassay for the simultaneous determination of postvaccination immunity against pertussis, diphtheria, and tetanus
Published in Analytical and bioanalytical chemistry (01-06-2017)“…A dot immunoassay for simultaneous semiquantitative detection of IgG against tetanus toxoid (Ttx) and diphtheria toxoid (Dtx) and qualitative detection of…”
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Conjugation of carbon coated-iron nanoparticles with biomolecules for NMR-based assay
Published in Colloids and surfaces, B, Biointerfaces (01-04-2019)“…[Display omitted] •Stable conjugates of iron-carbon nanoparticles with antibodies were synthesized.•The functionalization procedure is simple, well optimized…”
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