Search Results - "Khoury, Haia"
-
1
Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development
Published in Nature structural & molecular biology (01-03-2019)“…Germ cells manifest a unique gene expression program and regain totipotency in the zygote. Here, we perform Hi-C analysis to examine 3D chromatin organization…”
Get full text
Journal Article -
2
Abstract 7115: Mutational signatures in PDXs for improved understanding of drug response and companion biomarkers identification
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Genomic DNA editing is a continuous process that occurs during the entire cell life span. The type and frequency of these modifications can be related…”
Get full text
Journal Article -
3
Abstract 1304: Multiomic approaches to illuminate molecular drivers of breast cancer metastasis to the liver
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract The lack of knowledge around the mechanisms underlying metastatic progression is a major hurdle in achieving a durable response in the treatment of…”
Get full text
Journal Article -
4
Abstract 854: A pharmaco-pheno-multiomic integration analysis of pancreatic cancer: A highly predictive biomarker model of biomarkers of Gemcitabine/Abraxane sensitivity and resistance
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract The overall survival of patients diagnosed with Pancreatic Cancer remains low. Initial responses to current therapeutic interventions are below 50%,…”
Get full text
Journal Article