Search Results - "Khoury, H J"

Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin by Elf, S, Lin, R, Xia, S, Pan, Y, Shan, C, Wu, S, Lonial, S, Gaddh, M, Arellano, M L, Khoury, H J, Khuri, F R, Lee, B H, Boggon, T J, Fan, J, Chen, J

“…The oxidative pentose phosphate pathway (PPP) is crucial for cancer cell metabolism and tumor growth. We recently reported that targeting a key oxidative PPP…”
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Efficacy and safety of dasatinib in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blast phase by Cortes, J, Kim, D-W, Raffoux, E, Martinelli, G, Ritchie, E, Roy, L, Coutre, S, Corm, S, Hamerschlak, N, Tang, J-L, Hochhaus, A, Khoury, H J, Brümmendorf, T H, Michallet, M, Rege-Cambrin, G, Gambacorti-Passerini, C, Radich, J P, Ernst, T, Zhu, C, Van Tornout, J M A, Talpaz, M

“…Dasatinib is an inhibitor of BCR-ABL and SRC-family kinases for patients with imatinib-resistant or -intolerant chronic myelogenous leukemia (CML). In this…”
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FASH and MASH: female and male adult human phantoms based on polygon mesh surfaces: I. Development of the anatomy by Cassola, V F, Lima, V J de Melo, Kramer, R, Khoury, H J

“…Among computational models, voxel phantoms based on computer tomographic (CT), nuclear magnetic resonance (NMR) or colour photographic images of patients,…”
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Prognostic factors for outcomes in allogeneic transplantation for CML in the imatinib era: a CIBMTR analysis by Khoury, H J, Kukreja, M, Goldman, J M, Wang, T, Halter, J, Arora, M, Gupta, V, Rizzieri, D A, George, B, Keating, A, Gale, R P, Marks, D I, McCarthy, P L, Woolfrey, A, Szer, J, Giralt, S A, Maziarz, R T, Cortes, J, Horowitz, M M, Lee, S J

“…Allogeneic hematopoietic SCT is an effective treatment in accelerated (AP) or blast phase (BP) CML. Imatinib (IM) has transient but significant activity in…”
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The safety of Bosutinib for the treatment of chronic myeloid leukemia by Kong, Jee Hyun, Khoury, H J, Kim, Audrey Sunwha, Hill, Brittany Gray, Kota, Vamsi

“…Tyrosine kinase inhibitors (TKIs) are a potentially lifelong treatment for patients with chronic myeloid leukemia (CML). Adverse events (AEs) associated with…”
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MAX06 and FAX06: update of two adult human phantoms for radiation protection dosimetry by Kramer, R, Khoury, H J, Vieira, J W, Lima, V J M

“…The International Commission on Radiological Protection (ICRP) is currently preparing new recommendations which will replace those released in ICRP 1991, 1990…”
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Favorable impact of pre-transplant ATG on outcomes of reduced-intensity hematopoietic cell transplants from partially mismatched unrelated donors by Langston, A A, Prichard, J M, Muppidi, S, Nooka, A, Lechowicz, M J, Lonial, S, Sinha, R, Graiser, M, Kaufman, J L, Khoury, H J, Flowers, C R, Waller, E K

“…Reduced-intensity conditioning (RIC) permits allogeneic hematopoietic progenitor cell transplantation in patients who would not be considered candidates for…”
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All about FAX: a Female Adult voXel phantom for Monte Carlo calculation in radiation protection dosimetry by Kramer, R, Khoury, H J, Vieira, J W, Loureiro, E C M, Lima, V J M, Lima, F R A, Hoff, G

“…The International Commission on Radiological Protection (ICRP) has created a task group on dose calculations, which, among other objectives, should replace the…”
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Targeting 14-3-3 sensitizes native and mutant BCR-ABL to inhibition with U0126, rapamycin and Bcl-2 inhibitor GX15-070 by Dong, S, Kang, S, Lonial, S, Khoury, H J, Viallet, J, Chen, J

“…Small molecule tyrosine kinase inhibitors, such as imatinib, are effective therapies for BCR-ABL-mediated human leukemias. However, clinical drug resistance…”
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Vancomycin-resistant enterococcal bloodstream infections on a hematopoietic stem cell transplant unit: are the sick getting sicker? by DUBBERKE, E. R, HOLLANDS, J. M, GEORGANTOPOULOS, P, AUGUSTIN, K, DIPERSIO, J. F, MUNDY, L. M, KHOURY, H. J

“…Patients with hematologic malignancies and hematopoietic stem cell transplant (HSCT) recipients are at high risk for bacterial bloodstream infections (BSI)…”
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Biomarkers of immune activation to screen for severe, acute GVHD by August, K J, Chiang, K-Y, Bostick, R M, Flanders, W D, Waller, E K, Langston, A, Worthington-White, D, Rowland, P, Moore, K F, Khoury, H J, Horan, J T

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Radiation exposure to patients and medical staff in hepatic chemoembolisation interventional procedures in Recife, Brazil by Khoury, H J, Garzon, W J, Andrade, G, Lunelli, N, Kramer, R, de Barros, V S M, Huda, A

“…The purpose of this study was to evaluate patient and medical staff absorbed doses received from transarterial chemoembolisation of hepatocellular carcinoma,…”
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All about MAX: a male adult voxel phantom for Monte Carlo calculations in radiation protection dosimetry by Kramer, R, Vieira, J W, Khoury, H J, Lima, F R A, Fuelle, D

“…The MAX (Male Adult voXel) phantom has been developed from existing segmented images of a male adult body, in order to achieve a representation as close as…”
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European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia by Steegmann, J L, Baccarani, M, Breccia, M, Casado, L F, García-Gutiérrez, V, Hochhaus, A, Kim, D-W, Kim, T D, Khoury, H J, Le Coutre, P, Mayer, J, Milojkovic, D, Porkka, K, Rea, D, Rosti, G, Saussele, S, Hehlmann, R, Clark, R E

“…Most reports on chronic myeloid leukaemia (CML) treatment with tyrosine kinase inhibitors (TKIs) focus on efficacy, particularly on molecular response and…”
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Skeletal dosimetry in the MAX06 and the FAX06 phantoms for external exposure to photons based on vertebral 3D-microCT images by Kramer, R, Khoury, H J, Vieira, J W, Kawrakow, I

“…3D-microCT images of vertebral bodies from three different individuals have been segmented into trabecular bone, bone marrow and bone surface cells (BSC), and…”
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Practical management of toxicities associated with bosutinib in patients with Philadelphia chromosome-positive chronic myeloid leukemia by Khoury, H.J., Gambacorti-Passerini, C., Brümmendorf, T.H.

“…Bosutinib (SKI-606) is an oral, dual Src/Abl tyrosine kinase inhibitor (TKI) approved for treatment of patients with Philadelphia chromosome-positive (Ph+)…”
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Development of newborn and 1-year-old reference phantoms based on polygon mesh surfaces by Cassola, V F, Kramer, R, de Melo Lima, V J, de Oliveira Lira, C A B, Khoury, H J, Vieira, J W, Robson Brown, K

“…The purpose of this study is the development of paediatric reference phantoms for newborn and 1-year-old infants to be used for the calculation of organ and…”
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Organ doses and risks of computed tomography examinations in Recife, Brazil by Andrade, M E A, Borrás, C, Khoury, H J, Dias, S K, Barros, V S M

“…Computed tomography (CT) examinations have increased significantly in recent years due to technological innovations. In some industrialised countries, CT…”
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RADIATION DOSES TO ANAESTHETISTS DURING PROSTATIC ARTERY EMBOLIZATION INTERVENTIONAL PROCEDURES by Garzón, W J, Khoury, H J

“…The objective of this study was to assess the radiation doses received by anaesthetists from prostatic artery embolization (PAE) procedures. Ten PAE procedures…”
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Application of Response Surface Methodology (RSM) Technique to Optimize the Sintering Process of CaF2:Tm3 by Amorim, L. M. F., Asfora, V. K., Pimentel, M. F., Barros, V. S. M., Khoury, H. J.

“…The aim of this work was to optimize the sintering process of Tm-doped calcium fluoride in order to maximize the thermoluminescent (TL) response and the…”
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