Search Results - "Khouri, E"
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1
Wnt/β-catenin pathway and cell adhesion deregulation in CSDE1-related intellectual disability and autism spectrum disorders
Published in Molecular psychiatry (01-07-2021)“…Among the genetic factors playing a key role in the etiology of intellectual disabilities (IDs) and autism spectrum disorders (ASDs), several encode…”
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2
Relating growth and nutrition to site factors in young chestnut plantations established on agricultural and forest land in northern Spain
Published in Agroforestry systems (01-07-2010)“…The growth and nutritional status of 97 hybrid chestnut plantations on former agricultural land and forest land were studied in relation to site conditions…”
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3
EVALUATION OF THE MITOCHONDRIA RESPIROMETRIC FUNCTION IN THE CONDITIONS OF PATHOLOGIES OF VARIOUS GENESES
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (01-01-2019)“…The aim of the paper is to assess the change in the mitochondrial respirometric function under conditions of various pathologies. Materials and methods. The…”
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4
Modelling diameter distributions of birch (Betula alba L.) and pedunculate oak (Quercus robur L.) stands in Northwest Spain with the beta distribution
Published in Forest systems (01-12-2008)“…The diameter distribution of 125 and 172 permanent plots installed respectively in birch-dominated (Betula alba L.) and pedunculate oak-dominated (Quercus…”
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5
Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide
Published in Gene (15-02-1991)“…The baculovirus/insect cell system has been remarkably successful in yielding high levels of synthesis of many proteins which have been difficult to synthesize…”
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6
Contribution of the glutamine 19 side chain to transition-state stabilization in the oxyanion hole of papain
Published in Biochemistry (Easton) (01-09-1991)“…The existence of an oxyanion hole in cysteine proteases able to stabilize a transition-state complex in a manner analogous to that found with serine proteases…”
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7
Pharmacokinetics of the combination of fluvastatin and gemfibrozil
Published in The American journal of cardiology (13-07-1995)“…High-risk patients with dyslipidemias resistant to diet and single-agent pharmacotherapy may require combination therapy to achieve target levels of low…”
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Relationship among soil parameters, tree nutrition and site index of Pinus radiata D. Don in Asturias, NW Spain
Published in Forest systems (2010)“…Se estudia en 38 parcelas de 0,1 ha cada una las propiedades del suelo que más influyen en el índice de sitio (IS) de plantaciones de Pinus radiata D. Don de…”
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9
Primary Structure of the Merozoite Surface Antigen 1 of Plasmodium vivax Reveals Sequences Conserved Between Different Plasmodium Species
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1991)“…Merozoite surface antigen 1 (MSA1) of several species of plasmodia has been shown to be a promising candidate for a vaccine directed against the asexual blood…”
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10
Wnt/[beta]-catenin pathway and cell adhesion deregulation in CSDE1-related intellectual disability and autism spectrum disorders
Published in Molecular psychiatry (01-07-2021)“…Among the genetic factors playing a key role in the etiology of intellectual disabilities (IDs) and autism spectrum disorders (ASDs), several encode…”
Get full text
Journal Article -
11
Processing of the papain precursor. Purification of the zymogen and characterization of its mechanism of processing
Published in The Journal of biological chemistry (15-11-1991)“…The precursor of the cysteine protease papain has been expressed and secreted as propapain from insect cells infected with a recombinant baculovirus expressing…”
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12
Pharmacokinetics of the combination of fluvastatin and gemfibrozil
Published in The American journal of cardiology (01-07-1995)“…High-risk patients with dyslipidemias resistant todiet and single-agent pharmacotherapy may require combination therapy to achieve target levels of low density…”
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Journal Article -
13
Engineering of papain: selective alteration of substrate specificity by site-directed mutagenesis
Published in Biochemistry (Easton) (17-09-1991)“…The S2 subsite specificity of the plant protease papain has been altered to resemble that of mammalian cathepsin B by site-directed mutagenesis. On the basis…”
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14
A protein engineering study of the role of aspartate 158 in the catalytic mechanism of papain
Published in Biochemistry (Easton) (17-07-1990)“…The controversy concerning the various suggested roles for the side chain of Asp158 in the active site of papain has been clarified by using site-directed…”
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15
Secretion of functional papain precursor from insect cells. Requirement for N-glycosylation of the pro-region
Published in The Journal of biological chemistry (25-09-1990)“…The synthetic gene coding for the precursor of the cysteine protease papain (EC 3.4.22.2) has been expressed using the baculovirus/insect cell system. The…”
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16
A model to explain the pH-dependent specificity of cathepsin B-catalysed hydrolyses
Published in Biochemical journal (01-05-1991)“…1. Three synthetic substrates of cathepsin B (EC 3.4.22.1) with various amino acid residues at the P2 position (Cbz-Phe-Arg-NH-Mec, Cbz-Arg-Arg-NH-Mec and…”
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17
Importance of hydrogen-bonding interactions involving the side chain of Asp158 in the catalytic mechanism of papain
Published in Biochemistry (Easton) (01-06-1991)“…In a previous study, it was shown that replacing Asp158 in papain by Asn had little effect on activity and that the negatively charged carboxylate of Asp158…”
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18
Correlation of co-ordinated amino acid changes at the two-domain interface of cysteine proteases with protein stability
Published in Journal of molecular biology (20-03-1992)“…The engineering of a protein containing an alternative local residue packing for a set of side-chains has proven to be a major challenge because compositional,…”
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19
Risk Factors Associated With Small Bowel Adenocarcinoma in Crohn's Disease: A Case-Control Study
Published in The American journal of gastroenterology (01-07-2008)“…It is well established that Crohn's disease (CD) is associated with an increased risk of small bowel adenocarcinoma (SBA). The data concerning SBA risk factors…”
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20
Plasmodium vivax:recombination between potential allelic types of the merozoite surface protein MSP1 in parasites isolated from patients
Published in Experimental parasitology (01-03-1993)“…The merozoite surface protein MSP1, which is one of the most promising candidates for a malaria vaccine directed against erythrocytic stages, has been shown to…”
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