Search Results - "Khou, Sokchea"

Thymidine phosphorylase facilitates retinoic acid inducible gene-I induced endothelial dysfunction by Baris, Adrian, Fraile-Bethencourt, Eugenia, Eubanks, Jaiden, Khou, Sokchea, Anand, Sudarshan

“…Activation of nucleic acid sensors in endothelial cells (ECs) has been shown to drive inflammation across pathologies including cancer, atherosclerosis and…”
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Analysis of the Equilibrium Phase in Immune-Controlled Tumors Provides Hints for Designing Better Strategies for Cancer Treatment by Atsou, Kevin, Khou, Sokchea, Anjuère, Fabienne, Braud, Véronique M., Goudon, Thierry

“…When it comes to improving cancer therapies, one challenge is to identify key biological parameters that prevent immune escape and maintain an equilibrium…”
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Autofluorescence identifies highly phagocytic tissue-resident macrophages in mouse and human skin and cutaneous squamous cell carcinoma by Bourdely, Pierre, Petti, Luciana, Khou, Sokchea, Meghraoui-Kheddar, Aida, Elaldi, Roxane, Cazareth, Julie, Mossadegh-Keller, Noushine, Boyer, Julien, Sieweke, Michael H., Poissonnet, Gilles, Sudaka, Anne, Braud, Veronique M., Anjuère, Fabienne

“…Macrophages from human and mouse skin share phenotypic and functional features, but remain to be characterized in pathological skin conditions. Skin-resident…”
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The nucleic acid sensor RIG-I as an inducer of anti-tumor response by Fraile-Bethencourt, Eugenia, Khou, Sokchea, Anand, Sudarshan

“…Abstract The immune microenvironment plays a critical role in tumor progression. Recently, approaches to target Pattern Recognition Receptors (PRRs) have…”
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Role of RIG-I in tumor endothelium by Baris, Adrian, Anand, Sudarshan, Khou, Sokchea

“…Abstract The immune microenvironment plays a critical role in the efficacy of cancer treatment. The manipulation of cytosolic nucleic acid sensors has become a…”
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Abstract 3177: Intrinsic and acquired resistance to RIG-I induced anti-tumor responses by Fraile-Bethencourt, Eugenia, Khou, Sokchea, Anand, Sudarshan

“…Abstract The immune microenvironment plays a critical role in cancer orchestrating tumor progression and response to therapeutics. Strategies to manipulate the…”
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Abstract PO-095: Intrinsic and acquired resistance to RIG-I induced anti-tumor responses by Anand, Sudarshan, Fraile-Bethencourt, Eugenia, Khou, Sokchea

“…Abstract The immune microenvironment plays a critical role in cancer orchestrating tumor progression and response to therapeutics. Strategies to manipulate the…”
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Chymotrypsin activity signals to intestinal epithelium by protease‐activated receptor‐dependent mechanisms by Guignard, Simon, Saifeddine, Mahmoud, Mihara, Koichiro, Motahhary, Majid, Savignac, Magali, Guiraud, Laura, Sagnat, David, Sebbag, Mireille, Khou, Sokchea, Rolland, Corinne, Edir, Anissa, Bournet, Barbara, Buscail, Louis, Buscail, Etienne, Alric, Laurent, Camare, Caroline, Ambli, Mouna, Vergnolle, Nathalie, Hollenberg, Morley D., Deraison, Céline, Bonnart, Chrystelle

“…Background and Purpose Chymotrypsin is a pancreatic protease secreted into the lumen of the small intestine to digest food proteins. We hypothesized that…”
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Differential regulation of microRNA-15a by radiation affects angiogenesis and tumor growth via modulation of acid sphingomyelinase by Rana, Shushan, Espinosa-Diez, Cristina, Ruhl, Rebecca, Chatterjee, Namita, Hudson, Clayton, Fraile-Bethencourt, Eugenia, Agarwal, Anupriya, Khou, Sokchea, Thomas, Charles R., Anand, Sudarshan

“…Activation of acid sphingomyelinase (SMPD1) and the generation of ceramide is a critical regulator of apoptosis in response to cellular stress including…”
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Cutaneous Squamous Cell Carcinoma Development Is Associated with a Temporal Infiltration of ILC1 and NK Cells with Immune Dysfunctions by Luci, Carmelo, Bihl, Franck, Bourdely, Pierre, Khou, Sokchea, Popa, Alexandra, Meghraoui-Kheddar, Aida, Vermeulen, Ophelie, Elaldi, Roxane, Poissonnet, Gilles, Sudaka, Anne, Bozec, Alexandre, Bekri, Selma, Cazareth, Julie, Ponzio, Gilles, Barbry, Pascal, Rezzonico, Roger, Mari, Bernard, Braud, Veronique M., Anjuère, Fabienne

“…NK cells and tissue-resident innate lymphoid cells (ILCs) are innate effectors found in the skin. To investigate their temporal dynamics and specific functions…”
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Tumor-Associated Neutrophils Dampen Adaptive Immunity and Promote Cutaneous Squamous Cell Carcinoma Development by Khou, Sokchea, Popa, Alexandra, Luci, Carmelo, Bihl, Franck, Meghraoui-Kheddar, Aida, Bourdely, Pierre, Salavagione, Emie, Cosson, Estelle, Rubod, Alain, Cazareth, Julie, Barbry, Pascal, Mari, Bernard, Rezzonico, Roger, Anjuère, Fabienne, Braud, Veronique M.

“…Cutaneous squamous cell carcinoma (cSCC) development has been linked to immune dysfunctions but the mechanisms are still unclear. Here, we report a progressive…”
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Abstract LB224: Neoplastic immune mimicry potentiates breast cancer progression by Berens, Eric B., Khou, Sokchea, Huang, Elaine, Hoffman, Amber, Johnson, Briana, Werb, Zena, Heiser, Laura M., Coussens, Lisa M.

“…Abstract Dedifferentiation programs are commonly enacted during breast cancer progression where they enable novel cellular phenotypes. Increased cellular…”
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PAR2-dependent activation of GSK3β regulates the survival of colon stem/progenitor cells by Nasri, Imen, Bonnet, Delphine, Zwarycz, Bailey, d'Aldebert, Emilie, Khou, Sokchea, Mezghani-Jarraya, Raoudha, Quaranta, Muriel, Rolland, Corinne, Bonnart, Chrystelle, Mas, Emmanuel, Ferrand, Audrey, Cenac, Nicolas, Magness, Scott, Van Landeghem, Laurianne, Vergnolle, Nathalie, Racaud-Sultan, Claire

“…Protease-activated receptors PAR1 and PAR2 play an important role in the control of epithelial cell proliferation and migration. However, the survival of…”
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Abstract 3205: Role of RIG-I in tumor endothelium by Baris, Adrian M., Fraile-Bethencourt, Eugenia, Khou, Sokchea, Ruhl, Rebecca, Hudson, Clay, Anand, Sudarshan

“…Abstract The immune microenvironment plays a critical role in the efficacy of cancer treatment. The manipulation of cytosolic nucleic acid sensors has become a…”
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A Distinct Innate Immune Signature of Early Onset Colorectal Cancer by Gardner, Ivy H, Siddharthan, Ragavan, Watson, Katherine, Dewey, Elizabeth, Ruhl, Rebecca, Khou, Sokchea, Guan, Xiangnan, Xia, Zheng, Tsikitis, V Liana, Anand, Sudarshan

“…Despite a decrease in the prevalence of colorectal cancer (CRC) over the last 40 y, the prevalence of CRC in people under 50 y old is increasing around the…”
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