Search Results - "Khot, Prasanna D"

Novel Approach for Differentiating Shigella Species and Escherichia coli by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry by Khot, Prasanna D, Fisher, Mark A

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Optimization of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Analysis for Bacterial Identification by KHOT, Prasanna D, COUTURIER, Marc R, WILSON, Andrew, CROFT, Ann, FISHER, Mark A

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Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids by Sorensen, Matthew, Chandler, Courtney E., Gardner, Francesca M., Ramadan, Salma, Khot, Prasanna D., Leung, Lisa M., Farrance, Christine E., Goodlett, David R., Ernst, Robert K., Nilsson, Erik

“…Rapid infection diagnosis is critical to improving patient treatment and outcome. Recent studies have shown microbial lipids to be sensitive and selective…”
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Identification of Nocardia Species by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry by Khot, Prasanna D, Bird, Brian A, Durrant, Robert J, Fisher, Mark A

“…Matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Nocardia species remains challenging. By identifying 83.1%…”
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Sequencing and Analysis of Fungal rRNA Operons for Development of Broad-Range Fungal PCR Assays by Khot, Prasanna D, Ko, Daisy L, Fredricks, David N

“…rRNA genes are attractive targets for developing PCR assays targeting human fungal pathogens. Most studies have focused on the 18S rRNA gene, internal…”
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Comparison of quantitative real time PCR with Sequencing and ribosomal RNA-FISH for the identification of fungi in formalin fixed, paraffin-embedded tissue specimens by Rickerts, Volker, Khot, Prasanna D, Myerson, David, Ko, Daisy L, Lambrecht, Evelyn, Fredricks, David N

“…Identification of the causative agents of invasive fungal infections (IFI) is critical for guiding antifungal therapy. Cultures remain negative in a…”
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Development and optimization of quantitative PCR for the diagnosis of invasive aspergillosis with bronchoalveolar lavage fluid by Khot, Prasanna D, Ko, Daisy L, Hackman, Robert C, Fredricks, David N

“…The diagnosis of invasive pulmonary aspergillosis (IPA) remains challenging. Culture and histopathological examination of bronchoalveolar lavage (BAL) fluid…”
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A Small Subpopulation of Blastospores in Candida albicans Biofilms Exhibit Resistance to Amphotericin B Associated with Differential Regulation of Ergosterol and β-1,6-Glucan Pathway Genes by KHOT, Prasanna D, SUCI, Peter A, MILLER, R. Lance, NELSON, Raoul D, TYLER, Bonnie J

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PCR-based diagnosis of human fungal infections by Khot, Prasanna D, Fredricks, David N

“…PCR is a very appealing technology for the detection of human pathogens, but the detection of fungal pathogens is particularly challenging. Fungi have cell…”
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Mass Spectrometry in the Clinical Microbiology Laboratory, Part I: PCR-MS by Khot, Prasanna D., Ph.D, Fisher, Mark A., Ph.D

“…Abstract For some time, mass spectrometry (MS) has been an important diagnostic tool in the field of clinical chemistry; however, the technology is now making…”
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Candida albicans viability after exposure to amphotericin B: Assessment using metabolic assays and colony forming units by Khot, Prasanna D., Suci, Peter A., Tyler, Bonnie J.

“…Metabolic assays are a preferred method for evaluation of Candida albicans viability after exposure to antimicrobial agents in cases in which the culture is a…”
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Mass spectrometry in the clinical microbiology laboratory, part II: MALDI-TOF MS by Khot, Prasanna D., Ph.D, Fisher, Mark A., Ph.D

“…Abstract Recently, mass spectrometry methods have made significant inroads into the clinical microbiology laboratory. This transformation has been driven…”
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Isolation and Characterization of “Pseudomonas andersonii” from Four Cases of Pulmonary Granulomas and Emended Species Description by Simmon, Keith E, Fang, Deanna C, Tesic, Vera, Khot, Prasanna D, Giangeruso, Enrico, Bolesta, E Stephen, Wagner-Reiss, Katherine M, Fisher, Mark A, Petti, Cathy A, Han, Xiang Y, She, Rosemary C

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Enhanced fungal DNA-extraction from formalin-fixed, paraffin-embedded tissue specimens by application of thermal energy by Rickerts, Volker, Khot, Prasanna D., Ko, Daisy L., Fredricks, David N.

“…Determining the etiology of invasive fungal infections (IFI) is critical for patient management as fungi vary in their susceptibility to antifungals. However,…”
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Sequencing and Analysis of Fungal rRNA Operons for Development of Broad-Ranee Fungal PCR Assays by KHOT, Prasanna D, KO, Daisy L, FREDRICKS, David N

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A Small Subpopulation of Blastospores in Candida albicans Biofilms Exhibit Resistance to Amphotericin B Associated with Differential Regulation of Ergosterol and {szligbeta}-1,6-Glucan Pathway Genes by Khot, Prasanna D, Suci, Peter A, Miller, RLance, Nelson, Raoul D, Tyler, Bonnie J

“…The resistance of Candida albicans biofilms to a broad spectrum of antimicrobial agents has been well documented. Biofilms are known to be heterogeneous,…”
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Drug resistance of Candida albicans biofilms to amphotericin B by Khot, Prasanna D

“…The resistance of Candida albicans biofilms to a broad spectrum of antimicrobial agents poses a major clinical problem. Developing effective tools to quantify…”
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