Search Results - "Khorsandi, Layasadat"

Zinc oxide nanoparticles enhance expression of maspin in human breast cancer cells by Khorsandi, Layasadat, Farasat, Maryam

“…Toxic and apoptotic impacts of zinc oxide nanoparticle (ZNP) on different cancer cells have been reported. Maspin (a mammary serine protease inhibitor) as a…”
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Effects of Quercetin-Loaded Nanoparticles on MCF-7 Human Breast Cancer Cells by Niazvand, Firoozeh, Orazizadeh, Mahmoud, Khorsandi, Layasadat, Abbaspour, Mohammadreza, Mansouri, Esrafil, Khodadadi, Ali

“…Background and objectives: Previous studies have shown anti-tumor activity of quercetin (QT). However, the low bioavailability of QT has restricted its use…”
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Protective effects of zingerone on oxidative stress and inflammation in cisplatin-induced rat nephrotoxicity by Alibakhshi, Tuba, Khodayar, Mohammad Javad, Khorsandi, Layasadat, Rashno, Mohammad, Zeidooni, Leila

“…•The cisplatin dose-related nephrotoxicity limits its use, so efforts are ongoing to find ways to prevent or reduce cisplatin nephrotoxicity.•Zingerone has…”
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Chrysin attenuates traumatic brain injury-induced recognition memory decline, and anxiety/depression-like behaviors in rats: Insights into underlying mechanisms by Rashno, Masome, Ghaderi, Shahab, Nesari, Ali, Khorsandi, Layasadat, Farbood, Yaghoob, Sarkaki, Alireza

“…Rationale Cortical and hippocampal neuronal apoptosis and neuroinflammation are associated with behavioral deficits following traumatic brain injury (TBI)…”
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Wharton's Jelly Mesenchymal Stem Cells Derived Secretome Inhibits Colorectal Cancer Cell Growth Via Suppressing Mitophagy by Alidadi, Hadis, Khodayar, Mohammad Javad, Khorsandi, Layasadat

“…Abstract The anti-cancer effects of Wharton's jelly mesenchymal stem cells (WJSC)-derived secretome (WJSC-S) have been demonstrated in previous studies…”
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Ketotifen counteracts cisplatin-induced acute kidney injury in mice via targeting NF-κB/NLRP3/Caspase-1 and Bax/Bcl2/Caspase-3 signaling pathways by Mohtadi, Shokooh, Salehcheh, Maryam, Tabandeh, Mohammad Reza, Khorsandi, Layasadat, Khodayar, Mohammad Javad

“…Cisplatin (CIS) stands as one of the most effective chemotherapy drugs currently available. Despite its anticancer properties, the clinical application of CIS…”
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Possible mechanisms involved in the neuroprotective effects of chrysin against mild traumatic brain injury-induced spatial cognitive decline: An in vivo study in a rat model by Rashno, Masome, Sarkaki, Alireza, Farbood, Yaghoob, Rashno, Mohammad, Khorsandi, Layasadat, Naseri, Mohammad Kazem Gharib, Dianat, Mahin

“…Traumatic brain injury (TBI) is recognized as an important risk factor for cognitive deficits. The present study was designed to determine the potential…”
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Beneficial effects of quercetin on titanium dioxide nanoparticles induced spermatogenesis defects in mice by Khorsandi, Layasadat, Orazizadeh, Mahmoud, Moradi-Gharibvand, Nahid, Hemadi, Masoud, Mansouri, Esrafil

“…Many recent studies have demonstrated that most nanoparticles (NPs) have an adverse or toxic action on male germ cells. In present study, protective effect of…”
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Anti-diabetic effect of betulinic acid on streptozotocin-nicotinamide induced diabetic male mouse model by Birgani, Golshan Arzani, Ahangarpour, Akram, Khorsandi, Layasadat, Moghaddam, Hadi Fathi

“…Diabetes is a metabolic disease caused by abnormal insulin secretion or action. In the present study, the effects of betulinic acid (BA, a triterpene) are…”
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Gene expression in human liver fibrosis associated with Echinococcus granulosus sensu lato by Mirzavand, Somayeh, Rafiei, Abdollah, Teimoori, Ali, Khorsandi, Layasadat, Bahreini, Amin, Motamedfar, Azim, Beiromvand, Molouk

“…Liver fibrosis is a dynamic process that occurs in response to chronic liver disease resulting from factors such as chronic infections, autoimmune reactions,…”
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Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal by Radmehr, Vahid, Ahangarpour, Akram, Mard, Seyyed Ali, Khorsandi, Layasadat

“…Methylglyoxal (MG) provokes endoplasmic reticulum (ER) stress in β-cells and triggers pancreatic β-cell dysfunction. Crocin has anti-diabetic properties. The…”
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Myricetin Loaded Solid Lipid Nanoparticles Upregulate MLKL and RIPK3 in Human Lung Adenocarcinoma by Khorsandi, Layasadat, Mansouri, Esrafil, Rashno, Mohammad, Karami, Masoud Ali, Ashtari, Atefeh

“…Beneficial effects of MYC such as antioxidant, cytoprotective and antimicrobial activity have been investigated in various studies. The aim of the present…”
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Crocin attenuates endoplasmic reticulum stress in methylglyoxal-induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways by Radmehr, Vahid, Ahangarpour, Akram, Mard, Seyyed Ali, Khorsandi, Layasadat

“…Accumulation of methylglyoxal (MGO) occurs in diabetes. MicroRNA-204 is an important intracellular marker in the diagnosis of endoplasmic reticulum stress…”
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The effects of ozone and melatonin on busulfan-induced testicular damage in mice by Moghadam, Mahin Taheri, Dadfar, Reza, Khorsandi, Layasadat

“…Busulfan is one of the most common chemotherapeutic drugs and has the ability to induce apoptosis in testicular germ cells, which leads to infertility. In this…”
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Adipose-Derived Stem Cells' Secretome Attenuates Lesion Size and Parasite Loading in Leishmaniasis Caused by Leishmania Major in Mice by Khodkar, Iman, Saki, Jasem, Arjmand, Reza, Saki, Ghasem, Khorsandi, Layasadat

“…Stem cell-derived secretome (SE) released into the extracellular space contributes to tissue repair. The present study aimed to investigate the impact of…”
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Taurine attenuates valproic acid-induced hepatotoxicity via modulation of RIPK1/RIPK3/MLKL-mediated necroptosis signaling in mice by Khodayar, Mohammad Javad, Kalantari, Heibatullah, Khorsandi, Layasadat, Ahangar, Nematollah, Samimi, Azin, Alidadi, Hadis

“…Valproic acid (VPA) is known as a common drug in seizure and bipolar disorders treatment. Hepatotoxicity is the most important complication of VPA. Taurine…”
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Corrigendum to “vanillic acid attenuates effects of transient bilateral common carotid occlusion and reperfusion in rats” [Biomed. Pharmacother. 96 (2017) 667–674] by Khoshnam, Seyed Esmaeil, Sarkaki, Alireza, Khorsandi, Layasadat, Winlow, William, Badavi, Mohammad, Moghaddam, Hadi Fathi, Farbood, Yaghoob

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Protective effects of Chrysin against memory impairment, cerebral hyperemia and oxidative stress after cerebral hypoperfusion and reperfusion in rats by Shooshtari, Maryam Khombi, Sarkaki, Alireza, Mansouri, Seyed Mohammad Taghi, Badavi, Mohammad, Khorsandi, Layasadat, Ghasemi Dehcheshmeh, Mohammad, Farbood, Yaghoob

“…Stroke is devastating and a leading cause of morbidity and mortality worldwide. Cerebral ischemia-reperfusion and its subsequent reactive hyperemia lead to…”
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Chemotherapy Drugs Based on Solid Lipid Nanoparticles for Breast Cancer Treatment by Ashtari, Atefeh, Niazvand, Firoozeh, Khorsandi, Layasadat

“…Cancer is a group of diseases that include uncontrolled cell division and cell migration, as well as resistance to cell death [...]…”
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Cannabidiol attenuates arsenic-induced nephrotoxicity via the NOX4 and NF-κB pathways in mice by Vadizadeh, Ali, Salehcheh, Maryam, Kalantar, Hadi, Khorsandi, Layasadat, Rashno, Mohammad, Mahdavinia, Masoud

“…Cannabidiol (CBD) is a phenolic terpene compound with anticancer, antioxidant, anti-inflammatory, antibacterial, neuroprotective, and anticonvulsant…”
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