Search Results - "Khorram Khorshid, H R"

Dyads of GGC and GCC form hotspot colonies that coincide with the evolution of human and other great apes by Arabfard, M, Tajeddin, N, Alizadeh, S, Salesi, M, Bayat, H, Khorram Khorshid, H R, Khamse, S, Delbari, A, Ohadi, M

“…GGC and GCC short tandem repeats (STRs) are of various evolutionary, biological, and pathological implications. However, the fundamental two-repeats (dyads) of…”
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An exceptionally long CA-repeat in the core promoter of SCGB2B2 links with the evolution of apes and Old World monkeys by Nikkhah, M., Rezazadeh, M., Khorram Khorshid, H.R., Biglarian, A., Ohadi, M.

“…We have recently reported a genome-scale catalog of human protein-coding genes that contain “exceptionally long” STRs (≥6-repeats) in their core promoter,…”
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Association of interleukin-16 polymorphisms with disease progression and susceptibility in endometriosis by Azimzadeh, P., Khorram Khorshid, H. R., Akhondi, M. M., Shirazi, A.

“…Summary Interleukin‐16 (IL‐16) is a multifunctional pro‐inflammatory cytokine that was previously found in association with complex disorders, and it is now…”
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A GCC repeat in RAB26 undergoes natural selection in human and harbors divergent genotypes in late-onset Alzheimer's disease by Alizadeh, S, Khamse, S, Tajeddin, N, Khorram Khorshid, H R, Delbari, A, Ohadi, M

“…Although mainly located in genic regions and being mutation hotspots, intact blocks of CG-rich trinucleotide short tandem repeats (STRs) are largely overlooked…”
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Reversion of the human calreticulin gene promoter to the ancestral type as a result of a novel psychosis-associated mutation by Farokhashtiani, T., Mirabzadeh, A., Olad Nabi, M., Ghaem Magham, Z., Khorram Khorshid, H.R., Najmabadi, H., Ohadi, M.

“…Development-dependent, tissue-specific expression of the calreticulin (CALR) gene in the gray matter coincides with the expression of psychoses phenotypes. We…”
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Natural selection at the RASGEF1C (GGC) repeat in human and divergent genotypes in late-onset neurocognitive disorder by Jafarian, Z., Khamse, S., Afshar, H., Khorshid, H.R. Khorram, Delbari, A., Ohadi, M.

“…Expression dysregulation of the neuron-specific gene, RASGEF1C (RasGEF Domain Family Member 1C), occurs in late-onset neurocognitive disorders (NCDs), such as…”
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Novel mutations in the calreticulin gene core promoter and coding sequence in schizoaffective disorder by Olad Nabi, M., Mirabzadeh, A., Feizzadeh, G., Khorram Khorshid, H.R., Karimlou, M., Zarif Yeganeh, M., Asgharian, A.M., Najmabadi, H., Ohadi, M.

“…We have recently reported the first case of mutation in the core promoter sequence of the human calreticulin gene in a family case of schizoaffective disorder…”
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The association between Y chromosome microdeletion and recurrent pregnancy loss by Edalatkhah, H., Khorshid, H. R. Khorram, Sadeghi, M. R., Saliminejad, K., Bahreini, F., Ghorbian, S., Javadi, Gh. R., Kamali, K., Amirjannati, N.

“…Background : To date, the role of male factor contributing in evaluation of spontaneous recurrent pregnancy loss (RPL) has been less investigated and there is…”
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Novel extreme homozygote haplotypes at the human caveolin 1 gene upstream purine complex in sporadic Alzheimer's disease by Zarif Yeganeh, M., Mirabzadeh, A., Khorram Khorshid, H.R., Kamali, K., Heshmati, Y., Gozalpour, E., Veissy, K., Olad Nabi, M., Najmabadi, H., Ohadi, M.

“…Aberrant expression of the caveolin‐1 (CAV1) gene is associated with Alzheimer's disease (AD) brain. We have recently reported a polymorphic purine stretch…”
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A primate-specific functional GTTT-repeat in the core promoter of CYTH4 is linked to bipolar disorder in human by Rezazadeh, M., Gharesouran, J., Mirabzadeh, A., Khorram Khorshid, H.R., Biglarian, A., Ohadi, M.

“…Evidence of primate-specific genes and gene regulatory mechanisms linked to bipolar disorder (BD) lend support to evolutionary/adaptive processes in the…”
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Dominant and Protective Role of the CYTH4 Primate-Specific GTTT-Repeat Longer Alleles Against Neurodegeneration by Rezazadeh, M., Gharesouran, J., Movafagh, A., Taheri, M., Darvish, H., Emamalizadeh, B., Shahmohammadibeni, N., Khorram Khorshid, H. R., Behmanesh, M., Sahraian, M. A., Ohadi, M.

“…Primate-specific genes and regulatory mechanisms could provide insight into human brain functioning and disease. In a genome-scale analysis of the entire…”
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A Hypermutable Region in the DISP2 Gene Links to Natural Selection and Late-Onset Neurocognitive Disorders in Humans by Khamse, S., Alizadeh, S., Khorshid, H. R. Khorram, Delbari, A., Tajeddin, N., Ohadi, M.

“…(CCG) short tandem repeats (STRs) are predominantly enriched in genic regions, mutation hotspots for C to T truncating substitutions, and involved in various…”
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Association between Alzheimer's Disease and Apolipoprotein E Polymorphisms by Gozalpour, E, Kamali, K, Mohammd, K, Khorshid, Hr Khorram, Ohadi, M, Karimloo, M, Mirabzadeh, A, Fotouhi, A

“…Alzheimer's disease as a neurodegenerative disorder is the commonest type of dementia. A growing number of genes have been reported as the risk factors, which…”
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The association between sporadic Alzheimer’s disease and the human ABCA1 and APOE gene polymorphisms in Iranian population by Shahhusayni, M. H., Karimlu, M., Khorshid, H. R. Khorram, Gozalpour, E., Ohadi, M., Kamali, K.

“…Background: Apo lipoprotein E (APOE), which its ε4 allele has been reported as a risk factor in late onset Alzheimer’s disease (AD), is the main cholesterol…”
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Effects of Semelil (ANGIPARS™) on focal cerebral ischemia in male rats by Asadi-Shekaari, M, Eftekhar Vaghefi, H, Talakoub, A, Khorram Khorshid, Hr

“…Cerebral ischemia is one of the main causes of long term disability and death in aged populations. Many herbal drugs and extracts have been used for the…”
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Preclinical and phase 1 clinical safety of Setarud (IMOD super(TM)), a novel immunomodulator by Khairandish, P, Mohraz, M, Farzamfar, B, Abdollahi, M, Shahhosseiny, M H, Madani, H, Sadeghi, B, Heshmat, R, Gharibdoust, F, Khorram-Khorshid, H R

“…Background: A new herbal drug, Setarud (IMOD super(TM)) that has been shown to have beneficial immune effects was tested to determine its acute and chronic…”
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Studies on potential mutagenic and genotoxic activity of Setarud by Khorshid, KHR, Novitsky, YA, Abdollahi, M, Shahhosseiny, MH, Sadeghi, B, Madani, H, Rahimi, R, Farzamfar, B

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A clinical trial on the efficacy of IMOD in AIDS patients by Mohraz, M, Khairandish, P, Kazerooni, P A, Davarpanah, MA, Shahhosseiny, M H, Mahdavian, B, Vaziry, S, Shahriary, S, Kamali, K, Khorram, KHR, Heshmat, R, Farhadi, M, Gharibdoust, F

“…Background and the purpose of the study: Following the phase I clinical trial of the herbal drug IMOD in HIV/AIDS patients, further studies were required to…”
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Setarud (IMODTM) as a Multiherbal Drug with Promising Benefits in Animal and Human Studies: A Comprehensive Review of Biochemical and Cellular Evidences by Mohammadir, Azadeh, Khorram-Kh, H.R., Gharibdoos, Farhad, Abdollahi, Mohammad

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On the Protective Effects of IMOD and Silymarin Combination in a Rat Model of Acute Hepatic Failure Through Anti Oxidative Stress Mechanisms by Rahimi, H.R., Gholami, M., Khorram-Kh, H.R., Gharibdoos, F., Abdollahi, M.

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