Search Results - "Khorram, R."
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1
Natural selection at the RASGEF1C (GGC) repeat in human and divergent genotypes in late-onset neurocognitive disorder
Published in Scientific reports (28-09-2021)“…Expression dysregulation of the neuron-specific gene, RASGEF1C (RasGEF Domain Family Member 1C), occurs in late-onset neurocognitive disorders (NCDs), such as…”
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2
A GCC repeat in RAB26 undergoes natural selection in human and harbors divergent genotypes in late-onset Alzheimer's disease
Published in Gene (30-01-2024)“…Although mainly located in genic regions and being mutation hotspots, intact blocks of CG-rich trinucleotide short tandem repeats (STRs) are largely overlooked…”
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3
Novel crossover and recombination hotspots massively spread across primate genomes
Published in Biology direct (21-08-2024)“…The recombination landscape and subsequent natural selection have vast consequences forevolution and speciation. However, most of the crossover and…”
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4
A Hypermutable Region in the DISP2 Gene Links to Natural Selection and Late-Onset Neurocognitive Disorders in Humans
Published in Molecular neurobiology (01-11-2024)“…(CCG) short tandem repeats (STRs) are predominantly enriched in genic regions, mutation hotspots for C to T truncating substitutions, and involved in various…”
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5
Dyads of GGC and GCC form hotspot colonies that coincide with the evolution of human and other great apes
Published in BMC genetics (21-02-2024)“…GGC and GCC short tandem repeats (STRs) are of various evolutionary, biological, and pathological implications. However, the fundamental two-repeats (dyads) of…”
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6
An exceptionally long CA-repeat in the core promoter of SCGB2B2 links with the evolution of apes and Old World monkeys
Published in Gene (15-01-2016)“…We have recently reported a genome-scale catalog of human protein-coding genes that contain “exceptionally long” STRs (≥6-repeats) in their core promoter,…”
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7
A primate-specific functional GTTT-repeat in the core promoter of CYTH4 is linked to bipolar disorder in human
Published in Progress in neuro-psychopharmacology & biological psychiatry (02-01-2015)“…Evidence of primate-specific genes and gene regulatory mechanisms linked to bipolar disorder (BD) lend support to evolutionary/adaptive processes in the…”
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8
Association of interleukin-16 polymorphisms with disease progression and susceptibility in endometriosis
Published in International journal of immunogenetics (01-10-2016)“…Summary Interleukin‐16 (IL‐16) is a multifunctional pro‐inflammatory cytokine that was previously found in association with complex disorders, and it is now…”
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9
Reversion of the human calreticulin gene promoter to the ancestral type as a result of a novel psychosis-associated mutation
Published in Progress in neuro-psychopharmacology & biological psychiatry (30-03-2011)“…Development-dependent, tissue-specific expression of the calreticulin (CALR) gene in the gray matter coincides with the expression of psychoses phenotypes. We…”
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10
Dominant and Protective Role of the CYTH4 Primate-Specific GTTT-Repeat Longer Alleles Against Neurodegeneration
Published in Journal of molecular neuroscience (01-07-2015)“…Primate-specific genes and regulatory mechanisms could provide insight into human brain functioning and disease. In a genome-scale analysis of the entire…”
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Novel mutations in the calreticulin gene core promoter and coding sequence in schizoaffective disorder
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01-03-2010)“…We have recently reported the first case of mutation in the core promoter sequence of the human calreticulin gene in a family case of schizoaffective disorder…”
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12
The association between Y chromosome microdeletion and recurrent pregnancy loss
Published in Iranian red crescent medical journal (01-06-2012)“…Background : To date, the role of male factor contributing in evaluation of spontaneous recurrent pregnancy loss (RPL) has been less investigated and there is…”
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13
Novel extreme homozygote haplotypes at the human caveolin 1 gene upstream purine complex in sporadic Alzheimer's disease
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01-01-2010)“…Aberrant expression of the caveolin‐1 (CAV1) gene is associated with Alzheimer's disease (AD) brain. We have recently reported a polymorphic purine stretch…”
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14
Association between Alzheimer's Disease and Apolipoprotein E Polymorphisms
Published in Iranian journal of public health (01-01-2010)“…Alzheimer's disease as a neurodegenerative disorder is the commonest type of dementia. A growing number of genes have been reported as the risk factors, which…”
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15
Cost of Ownership/Yield Enhancement of High Volume Immersion Lithography Using Topcoat-Less Resists
Published in IEEE transactions on semiconductor manufacturing (01-02-2012)“…The complexity and extra cost associated with a resist topcoat layer has motivated the industry to transition to topcoat-less (TC-less) resist processes. By…”
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The association between sporadic Alzheimer’s disease and the human ABCA1 and APOE gene polymorphisms in Iranian population
Published in Iranian red crescent medical journal (01-04-2011)“…Background: Apo lipoprotein E (APOE), which its ε4 allele has been reported as a risk factor in late onset Alzheimer’s disease (AD), is the main cholesterol…”
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17
SYNTHESIS AND CORROSION PROTECTION BEHAVIOR OF EPOXYTiO2-MICACEOUS IRON OXIDE NANO - COMPOSITE COATING ON St-37
Published in Iranian journal materials science and engineering (Online) (01-03-2016)“…The micro layers micaceous iron oxide and nano-TiO 2 were incorporated into the epoxy resin by mechanical mixing and sonication process. Optical micrographs…”
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18
Cost of Ownership/Yield Enhancement of High Volume Immersion Lithography Using Topcoat-Less Resists
Published in IEEE transactions on semiconductor manufacturing (01-05-2011)“…The complexity and extra cost associated with a resist topcoat (TC) layer has motivated the industry to transition to TC-less resist processes. By switching to…”
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Journal Article Conference Proceeding -
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Effects of Semelil (ANGIPARS™) on focal cerebral ischemia in male rats
Published in Daru (2010)“…Cerebral ischemia is one of the main causes of long term disability and death in aged populations. Many herbal drugs and extracts have been used for the…”
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MEMS manufacturing solutions
Published in 2015 26th Annual SEMI Advanced Semiconductor Manufacturing Conference (ASMC) (01-05-2015)“…Reducing time to market and cost-of-ownership is essential to MEMS makers. Therefore, lithography tools that continue to provide new, flexible, and versatile…”
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Conference Proceeding