Search Results - "Khorattanakulchai, Narach"
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Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana
Published in Scientific reports (19-10-2020)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the ongoing global outbreak of coronavirus disease (COVID-19) which is a…”
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Emergence of monkeypox: Another concern amidst COVID-19 crisis
Published in Asian Pacific journal of tropical medicine (01-05-2022)Get full text
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Plant-produced SARS-CoV-2 receptor binding domain (RBD) variants showed differential binding efficiency with anti-spike specific monoclonal antibodies
Published in PloS one (11-08-2021)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the ongoing coronavirus disease (COVID-19) pandemic which is characterized by…”
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SARS-CoV-2 variants: A continuing threat to global health
Published in Asian Pacific journal of tropical medicine (01-01-2022)Get full text
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Functional Characterization of Pembrolizumab Produced in Nicotiana benthamiana Using a Rapid Transient Expression System
Published in Frontiers in plant science (09-09-2021)“…The striking innovation and clinical success of immune checkpoint inhibitors (ICIs) have undoubtedly contributed to a breakthrough in cancer immunotherapy…”
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Antitumor effect of plant-produced anti-CTLA-4 monoclonal antibody in a murine model of colon cancer
Published in Frontiers in plant science (29-08-2023)“…Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is an immune checkpoint regulator exclusively expressed on T cells that obstructs the cell’s effector…”
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A recombinant subunit vaccine candidate produced in plants elicits neutralizing antibodies against SARS-CoV-2 variants in macaques
Published in Frontiers in plant science (28-09-2022)“…Since the outbreak of the coronavirus disease (COVID) pandemic in 2019, the development of effective vaccines to combat the infection has been accelerated…”
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Characterization of plant produced VHH antibodies against cobra venom toxins for antivenom therapy
Published in Biotechnology reports (Amsterdam, Netherlands) (01-06-2024)“…•Single variable domains (VHH) are promising candidates for various applications in biomedical research, diagnosis, and therapy.•The recombinant VHH-Fc…”
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Immunogenicity and efficacy of recombinant subunit SARS-CoV-2 vaccine candidate in the Syrian hamster model
Published in Biotechnology reports (Amsterdam, Netherlands) (01-03-2023)“…•Efficacy of Baiya SARS-CoV-2 Vax 1 was tested in hamster model.•Baiya SARS-CoV-2 Vax 1 provided protection against SARS-CoV-2 challenge in animals.•Clinical…”
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Plant-Produced S1 Subunit Protein of SARS-CoV-2 Elicits Immunogenic Responses in Mice
Published in Vaccines (Basel) (01-11-2022)“…SARS-CoV-2 is responsible for the ongoing COVID-19 pandemic. The virus spreads rapidly with a high transmission rate among humans, and hence virus management…”
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Recombinant human dentin matrix protein 1 (DMP1) induces the osteogenic differentiation of human periodontal ligament cells
Published in Biotechnology reports (Amsterdam, Netherlands) (01-09-2019)“…•Recombinant human dentin matrix protein 1 (DMP1) can be produced in Escherichia coli.•E. coli produced DMP1 could induce the expression of osteogenic-related…”
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SARS‐CoV‐2 omicron variant: Could it be another threat?
Published in Journal of medical virology (01-04-2022)Get full text
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Binding of PmClipSP2 to microbial cell wall components and activation of the proPO-activating system in the black tiger shrimp Penaeus monodon
Published in Developmental and comparative immunology (01-12-2017)“…Clip domain serine proteinases (ClipSPs) play an important role in the prophenoloxidase-activating (proPO) system. In the shrimp Penaeus monodon, the ClipSP…”
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Osteopontin induces osteogenic differentiation by human periodontal ligament cells via calcium binding domain–ALK‐1 interaction
Published in Journal of periodontology (1970) (01-02-2022)“…Background Recently we have generated recombinant human osteopontin (rhOPN) using a plant platform (Nicotiana benthamiana) and demonstrated, when coated on…”
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Development of Plant-Derived Bispecific Monoclonal Antibody Targeting PD-L1 and CTLA-4 against Mouse Colorectal Cancer
Published in Planta medica (01-04-2024)“…Checkpoint blockade immunotherapy has revolutionized cancer treatment, with monoclonal antibodies targeting immune checkpoints, yielding promising clinical…”
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Plant-produced SARS-CoV-2 receptor binding domain
Published in PloS one (11-08-2021)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the ongoing coronavirus disease (COVID-19) pandemic which is characterized by…”
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Receptor binding domain proteins of SARS‐CoV‐2 variants produced in Nicotiana benthamiana elicit neutralizing antibodies against variants of concern
Published in Journal of medical virology (01-09-2022)“…The constantly emerging severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) variants of concerns (VOCs) with mutations in the receptor‐binding domain…”
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Preclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvant
Published in Vaccine (24-04-2023)“…Cost-effective, and accessible vaccines are needed for mass immunization to control the ongoing coronavirus disease 2019 (COVID-19), especially in low- and…”
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Preclinical evaluation of a plant-derived SARS-CoV-2 subunit vaccine: Protective efficacy, immunogenicity, safety, and toxicity
Published in Vaccine (30-07-2022)“…•Efficacy, safety and toxicity of Baiya SARS-CoV-2 Vax 1 was tested in animal models.•Baiya SARS-CoV-2 Vax 1 provided protection against SARS-CoV-2…”
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Characterization of plant produced V HH antibodies against cobra venom toxins for antivenom therapy
Published in Biotechnology reports (Amsterdam, Netherlands) (01-06-2024)“…Cobra ( ) venom contains many toxins including α-neurotoxin (αNTX) and phospholipase A2 (PLA2), which can cause neurodegeneration, respiratory failure, and…”
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