Search Results - "Khoo, Cheen P"
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Lentiviral delivered aflibercept OXB-203 for treatment of neovascular AMD
Published in Molecular therapy. Methods & clinical development (14-09-2023)“…Neovascular age-related macular degeneration (nAMD) is a leading cause of blindness in the aging population, with vascular endothelial growth factor (VEGF)…”
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The angiogenic properties of mesenchymal stem/stromal cells and their therapeutic potential
Published in British medical bulletin (01-12-2013)“…Blood vessel formation is fundamental to development, while its dysregulation can contribute to serious disease. Expectations are that hundreds of millions of…”
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miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration
Published in Scientific reports (09-03-2017)“…Circulating endothelial colony forming cells (ECFCs) contribute to vascular repair where they are a target for therapy. Since ECFC proliferative potential is…”
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Association of Maternal Antiangiogenic Profile at Birth With Early Postnatal Loss of Microvascular Density in Offspring of Hypertensive Pregnancies
Published in Hypertension (Dallas, Tex. 1979) (01-09-2016)“…Offspring of hypertensive pregnancies are more likely to have microvascular rarefaction and increased blood pressure in later life. We tested the hypothesis…”
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Junctional Adhesion Molecule‐A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4
Published in Stem cells (Dayton, Ohio) (01-06-2016)“…Hematopoietic stem/progenitor cells (HSPCs) reside in specialized bone marrow microenvironmental niches, with vascular elements (endothelial/mesenchymal…”
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A novel function for the haemopoietic supportive murine bone marrow MS-5 mesenchymal stromal cell line in promoting human vasculogenesis and angiogenesis
Published in British journal of haematology (01-05-2012)“…Summary The bone marrow contains specific microenvironmental stem cell niches that maintain haemopoiesis. CXCL12‐expressing mesenchymal stromal cells are…”
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The hematopoietic chemokine CXCL12 promotes integration of human endothelial colony forming cell-derived cells into immature vessel networks
Published in Stem cells and development (15-11-2014)“…Proangiogenic factors, vascular endothelial growth factor (VEGF), and fibroblast growth factor-2 (FGF-2) prime endothelial cells to respond to "hematopoietic"…”
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Endothelial progenitor cells and their potential therapeutic applications
Published in Regenerative medicine (01-11-2008)“…Endothelial progenitor cells (EPCs) are derived from the bone marrow (BM) and peripheral blood (PB), contributing to tissue repair in various pathological…”
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Comparison of two angiogenic quantification methods in the Matrigel assay
Published in Vascular pharmacology (01-05-2012)Get full text
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Effects of obstetric factors and storage temperatures on the yield of endothelial colony forming cells from umbilical cord blood
Published in Angiogenesis (London) (01-09-2011)“…As umbilical cord blood (UCB) is a rich source of endothelial colony-forming cells (ECFC), our aim was twofold: (1) to examine potential obstetric selection…”
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Effects of obstetric factors and storage temperatures on the yield of endothelial colony forming cells from umbilical cord blood
Published in Vascular pharmacology (01-05-2012)Get full text
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