Search Results - "Khoo, C. H."

Wolbachia Establishment and Invasion in an Aedes aegypti Laboratory Population by Xi, Zhiyong, Khoo, Cynthia C. H, Dobson, Stephen L

“…A proposed strategy to aid in controlling the growing burden of vector-borne disease is population replacement, in which a natural vector population is…”
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The RNA interference pathway affects midgut infection- and escape barriers for Sindbis virus in Aedes aegypti by Khoo, Cynthia C H, Piper, Joseph, Sanchez-Vargas, Irma, Olson, Ken E, Franz, Alexander W E

“…The RNA interference (RNAi) pathway acts as an innate antiviral immune response in Aedes aegypti, modulating arbovirus infection of mosquitoes. Sindbis virus…”
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A meta-epidemiological study of bias in randomized clinical trials of open and laparoscopic surgery by Amer, M A, Herbison, G P, Grainger, S H, Khoo, C H, Smith, M D, McCall, J L

“…Blinding, random sequence generation, and allocation concealment are established strategies to minimize bias in RCTs. Meta-epidemiological studies of drug…”
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Thyroid autoantibody profiles in ophthalmic dominant and thyroid dominant Graves' disease differ and suggest ophthalmopathy is a multiantigenic disease by Goh, S. Y., Ho, S. C., Seah, L. L., Fong, K. S., Khoo, D. H. C.

“…Summary background  Thyroid‐associated ophthalmopathy (TAO) occurs in 25–50% of patients with Graves’ disease (GD) and is occasionally seen in hypothyroid…”
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Network meta‐analysis of surgical management of gastro‐oesophageal reflux disease in adults by Amer, M. A., Smith, M. D., Khoo, C. H., Herbison, G. P., McCall, J. L.

“…Background Proton pump inhibitors are the mainstay of treatment for gastro‐oesophageal reflux disease, but are associated with ongoing costs and side‐effects…”
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Transgene-mediated suppression of the RNA interference pathway in Aedes aegypti interferes with gene silencing and enhances Sindbis virus and dengue virus type 2 replication by Khoo, C. C. H., Doty, J. B., Heersink, M. S., Olson, K. E., Franz, A. W. E.

“…RNA interference (RNAi) is the major innate antiviral pathway in Aedes aegypti that responds to replicating arboviruses such as dengue virus (DENV) and Sindbis…”
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Interspecific transfer of Wolbachia into the mosquito disease vector Aedes albopictus by Xi, Zhiyong, Khoo, Cynthia C.H, Dobson, Stephen L

“…-infected males are used to suppress mosquito egg hatch. We discuss the results in relation to developing appropriate…”
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Isolation of midgut escape mutants of two American genotype dengue 2 viruses from Aedes aegypti by Khoo, Cynthia CH, Doty, Jeffrey B, Held, Nicole L, Olson, Ken E, Franz, Alexander WE

“…BACKGROUND: Several studies have shown that American genotype dengue 2 viruses (DENV2) have reduced viral fitness in the mosquito vector, Aedes aegypti,…”
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Infection, growth and maintenance of Wolbachia pipientis in clonal and non-clonal Aedes albopictus cell cultures by Khoo, C C H, Venard, C M P, Fu, Y, Mercer, D R, Dobson, S L

“…Insect cell lines provide useful in vitro models for studying biological systems, including interactions between mosquitoes and obligate intracellular…”
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Mutations in Potassium Channel Kir2.6 Cause Susceptibility to Thyrotoxic Hypokalemic Periodic Paralysis by Ryan, Devon P., Dias da Silva, Magnus R., Soong, Tuck Wah, Fontaine, Bertrand, Donaldson, Matt R., Kung, Annie W.C., Jongjaroenprasert, Wallaya, Liang, Mui Cheng, Khoo, Daphne H.C., Cheah, Jin Seng, Ho, Su Chin, Bernstein, Harold S., Maciel, Rui M.B., Brown, Robert H., Ptáček, Louis J.

“…Thyrotoxic hypokalemic periodic paralysis (TPP) is characterized by acute attacks of weakness, hypokalemia, and thyrotoxicosis of various etiologies. These…”
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Analysis of TP53 gene expression and p53 level of human hypopharyngeal FaDu (HTB-43) head and neck cancer cell line after microRNA-181a inhibition by Cheah, Y K, Cheng, R W, Yeap, S K, Khoo, C H, See, H S

“…The identification of new biomarkers for early detection of highly recurrent head and neck cancer is urgently needed. MicroRNAs (miRNAs) are small and…”
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Effects of genetic immunization of Swiss outbred mice with human thyroid stimulating hormone receptor cDNA plasmids harboring gain-of-function mutations by Ho, Su-Chin, Goh, Sui-Sin, Kee, Irene H C, Chow, Pierce K H, Yeo, Chin-Pin, Khoo, Daphne H C

“…Animal models of Graves’ disease have been generated in recent years with various vaccination protocols using wild-type TSH receptor. In this study, we report…”
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Detection of thyroid peroxidase mRNA and protein in orbital tissue by Lai, Oi Fah, Zaiden, Norazean, Goh, Sui Sin, Mohamed, Nur-Ezan, Seah, Lay Leng, Fong, Kee Siew, Estienne, Valerie, Carayon, Pierre, Ho, Su Chin, Khoo, Daphne H C

“…Objective: We have previously reported that the absence of thyroid peroxidase antibodies (TPOAb) in Graves’ disease (GD) was associated with an increased risk…”
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Diabetes outcomes in specialist and general practitioner settings in Singapore: challenges of right-siting by Wee, Shiou Liang, Tan, Caren G P, Ng, Hilda S H, Su, Scott, Tai, Virginia U M, Flores, John V P G, Khoo, Daphne H C

“…The Singapore public healthcare system has increasingly used the term "right-siting" to describe the principle that stable chronic disease patients should be…”
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Comparison of transgene expression in Aedes aegypti generated by mariner Mos1 transposition and ΦC31 site-directed recombination by Franz, A. W. E., Jasinskiene, N., Sanchez-Vargas, I., Isaacs, A. T., Smith, M. R., Khoo, C. C. H., Heersink, M. S., James, A. A., Olson, K. E.

“…Transgenic mosquitoes generated by transposable elements (TEs) often poorly express transgenes owing to position effects. To avoid these effects, the ΦC31…”
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Stability and loss of a virus resistance phenotype over time in transgenic mosquitoes harbouring an antiviral effector gene by Franz, A.W.E, Sanchez-Vargas, I, Piper, J, Smith, M.R, Khoo, C.C.H, James, A.A, Olson, K.E

“…Transgenic Aedes aegypti were engineered to express a virus-derived, inverted repeat (IR) RNA in the mosquito midgut to trigger RNA interference (RNAi) and…”
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Examining the STEM-Science Achievement Test (SSAT) Using Rasch Dichotomous Measurement Model by Jamaludin, J., Lay, Y. F., Khoo, C. H., Leong, A. S. Y.

“…The main purpose of this study is to develop a valid and reliable instrument to measure the STEM-Science achievement of primary school students in Malaysia…”
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Initial experience of laparoscopic retroperitoneal partial nephrectomy in an academic hospital in Malaysia by Khoo, H C, Lim, L Y, Shukor, S, Zainal Adwin, Z A, Zulkifli, M Z, Fam, X I

“…Laparoscopic retroperitoneal partial nephrectomy (LRPN) is a technically demanding kidney surgery due to the limited space and unfamiliar approach in the…”
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A Germline Mutation of the Thyrotropin Receptor Gene Associated with Thyrotoxicosis and Mitral Valve Prolapse in a Chinese Family by Khoo, D. H. C., Parma, J., Rajasoorya, C., Ho, S. C., Vassart, G.

“…Activating mutations of the TSH receptor (TSH-R) have been reported to result in toxic adenomas, multinodular goiters, sporadic neonatal hyperthyroidism, and…”
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Malaysian consensus statement on FDG PET-CT reporting format for lymphoma by Tan, T H, Wong, T H, Khoo, C H, Mahaletchumy, T, Ng, C S, Ghazali, M W

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