Search Results - "Khomutov, A"
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Synthesis of 2-Methylidene Spermidine and its N1-Acetylated Derivative
Published in Russian journal of bioorganic chemistry (2022)“…— Simple and practical synthetic protocols have been developed for the preparation of earlier unknown 2-methylidene derivatives of spermidine and N 1…”
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2
Interaction of DNA Methyltransferase Dnmt3a with Phosphorus Analogs of S-Adenosylmethionine and S-Adenosylhomocysteine
Published in Molecular biology (New York) (01-08-2023)“…Enzymatic methyltransferase reactions are of crucial importance for cell metabolism. S -Adenosyl- L -methionine (AdoMet) is a main donor of the methyl group…”
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3
C-Methylated Analogs of Spermine and Spermidine: Synthesis and Biological Activity
Published in Russian journal of bioorganic chemistry (01-11-2019)“…— Biogenic polyamines spermine and spermidine are present in eukaryotic cells in micro- and millimolar concentrations, that determines the multiplicity of…”
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Antibacterial Activity of Peptide Derivatives of Phosphinothricin against Multidrug-Resistant Klebsiella pneumoniae
Published in Molecules (Basel, Switzerland) (27-01-2023)“…The fast spread of bacteria that are resistant to many classes of antibiotics (multidrug resistant) is a global threat to human and animal health with a…”
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Identification Features of the Transition and Intermediate Layers in the Polygonal Peatlands in Northwestern Siberia
Published in Doklady earth sciences (01-06-2021)“…The upper part of the subsurface component of the Earth’s cryosphere—polygonal peatlands—are considered in this paper. The polygonal peatlands are widespread…”
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Seasonal Thawing Local Changes Indicators for UAV-Based Cryolithozone Mapping
Published in Doklady earth sciences (01-03-2020)“…Remote sensing methods make it possible to evaluate the reaction of the cryolithozone and tundra landscapes in hard-to-reach Arctic areas based on the…”
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Comparative Study of Methanogenic Pathways in the Sediments of Thermokarst and Polygenetic Yamal Lakes
Published in Microbiology (New York) (01-03-2021)“…— Comparative study of methanogen diversity and potential activity of different methanogenic pathways in the sediments of young thermokarst and mature…”
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Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds
Published in Frontiers in pharmacology (15-12-2023)“…Oligoarginine peptides, known mostly for their cell-penetrating properties, are also inhibitors of the nicotinic acetylcholine receptors (nAChRs). Since…”
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9
Identification of a novel substrate-derived spermine oxidase inhibitor
Published in Actanaturae (01-07-2020)“…Homeostasis of the biogenic polyamines spermine (Spm) and spermidine (Spd), present in M-mM concentrations in all eukaryotic cells, is precisely regulated by…”
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Synthesis of chalcones with methylenedioxypolymethoxy fragments based on plant metabolites and study of their antiproliferative properties
Published in Russian chemical bulletin (01-07-2023)“…Natural allylpolyalkoxybenzenes were used to synthesize polyalkoxychalcones featuring various conformations, including β-methyl-substituted S - trans…”
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Insights into the Functioning of the D-amino Acid Transaminase from Haliscomenobacter Hydrossis via a Structural and Spectral Analysis of its Complex with 3-Aminooxypropionic Acid
Published in Actanaturae (12-11-2024)“…Pyridoxal 5'-phosphate-dependent enzymes play a crucial role in nitrogen metabolism. Carbonyl compounds, such as O-substituted hydroxylamines, stand out among…”
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Features of the Destruction of a Microjet of a Diluted Polymer Solution into Main and Satellite Microdrops under the Action of an External Vibrational Impact
Published in Technical physics (01-12-2022)“…An experimental study of the morphology of a laminar microjet flow of dilute aqueous solutions of sodium alginate with and without the addition of hydroxyethyl…”
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13
A Desmethylphosphinothricin Dipeptide Derivative Effectively Inhibits Escherichia coli and Bacillus subtilis Growth
Published in Biomolecules (Basel, Switzerland) (26-09-2023)“…New antibiotics are unquestionably needed to fight the emergence and spread of multidrug-resistant bacteria. To date, antibiotics targeting bacterial central…”
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14
Organophosphorus S -adenosyl- L -methionine mimetics: synthesis, stability, and substrate properties
Published in Frontiers in chemistry (01-08-2024)“…-Adenosyl-l-methionine (SAM)-mediated methylation of biomolecules controls their function and regulates numerous vital intracellular processes. Analogs of SAM…”
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15
Environment, vegetation and greenness (NDVI) along the North America and Eurasia Arctic transects
Published in Environmental research letters (01-01-2012)“…Satellite-based measurements of the normalized difference vegetation index (NDVI; an index of vegetation greenness and photosynthetic capacity) indicate that…”
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Aminooxy analog of histamine is an efficient inhibitor of mammalian L-histidine decarboxylase: combined in silico and experimental evidence
Published in Amino acids (01-03-2014)“…Histamine plays highlighted roles in the development of many common, emergent and rare diseases. In mammals, histamine is formed by decarboxylation of…”
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Aminooxy adsorbents derived from sephareose and toyopearl
Published in Russian journal of bioorganic chemistry (01-09-2016)“…Convenient synthetic schemes being suitable for the preparation of aminooxy-Sepharose and hydroxylamine-containing Toyopearl with capacity of 0.35–0.015 mmols…”
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C -Methylated Spermidine Derivatives: Convenient Syntheses and Antizyme-Related Effects
Published in Biomolecules (Basel, Switzerland) (31-05-2023)“…The biogenic polyamines, spermidine (Spd) and spermine (Spm), are present at millimolar concentrations in all eukaryotic cells, where they participate in the…”
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Synthesis and Antiproliferative Activity of Triphenylphosphonium Derivatives of Natural Allylpolyalkoxybenzenes
Published in ACS omega (01-02-2022)“…Derivatives of natural allylpolyalkoxybenzenes conjugated to triphenylphosphonium (TPP) cations by aliphatic linkers of three, six, seven, and eight atoms were…”
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Biogenic polyamines spermine and spermidine activate RNA polymerase and inhibit RNA helicase of hepatitis C virus
Published in Biochemistry (Moscow) (01-10-2012)“…Influence of the biogenic polyamines spermine, spermidine, and putrescine as well as their derivatives on the replication enzymes of hepatitis C virus (HCV)…”
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