Search Results - "Kholmatov, Maxim M."
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Changes in the concentration of EGFR-mutated plasma DNA in the first hours of targeted therapy allow the prediction of tumor response in patients with EGFR-driven lung cancer
Published in International journal of clinical oncology (01-05-2022)“…Purpose This study aimed to analyze changes in the plasma concentration of EGFR-mutated circulating tumor DNA (ctDNA) occurring immediately after the start of…”
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Comparative analysis of expression of mutant and wild-type alleles is essential for reliable PCR-based detection of MET exon 14 skipping
Published in Biochimie (01-10-2019)“…MET exon 14 skipping (exon 14Δ) mutations are associated with tumor sensitivity to a number of tyrosine kinase inhibitors, however clinical testing for MET…”
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Variability in lung cancer response to ALK inhibitors cannot be explained by the diversity of ALK fusion variants
Published in Biochimie (01-11-2018)“…Multiple laboratory evidences indicate that distinct variants of ALK translocations differ in their biochemical properties and responsiveness to ALK tyrosine…”
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Content of circulating tumor DNA depends on the tumor type and the dynamics of tumor size, but is not influenced significantly by physical exercise, time of the day or recent meal
Published in Cancer genetics (01-08-2021)“…•The amount of ctDNA is higher in patients with tumor progression vs. subjects with the control of malignant disease.•Time of the day, recent meal or moderate…”
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Abstract 717: Presence of distant metastases and disease progression but not tumor size, lymph node involvement, circadian rhythms, prior physical exercise or recent food consumption influence the concentration of circulating tumor DNA in cancer patients
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Liquid biopsy is potentially useful for early tumor detection, monitoring of cancer disease during treatment and diagnosis of therapy-related…”
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