Search Results - "Khokhlova, Vera"
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Histotripsy: A Method for Mechanical Tissue Ablation with Ultrasound
Published in Annual review of biomedical engineering (01-07-2024)“…Histotripsy is a relatively new therapeutic ultrasound technology to mechanically liquefy tissue into subcellular debris using high-amplitude focused…”
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Acoustic holography as a metrological tool for characterizing medical ultrasound sources and fields
Published in The Journal of the Acoustical Society of America (01-09-2015)“…Acoustic holography is a powerful technique for characterizing ultrasound sources and the fields they radiate, with the ability to quantify source vibrations…”
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3
Noninvasive acoustic manipulation of objects in a living body
Published in Proceedings of the National Academy of Sciences - PNAS (21-07-2020)“…In certain medical applications, transmitting an ultrasound beam through the skin to manipulate a solid object within the human body would be beneficial. Such…”
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4
Dynamic Mode Decomposition for Transient Cavitation Bubbles Imaging in Pulsed High-Intensity Focused Ultrasound Therapy
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-05-2024)“…Pulsed high-intensity focused ultrasound (pHIFU) can induce sparse de novo inertial cavitation without the introduction of exogenous contrast agents, promoting…”
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5
Characterization of a multi-element clinical HIFU system using acoustic holography and nonlinear modeling
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-08-2013)“…High-intensity focused ultrasound (HIFU) is a treatment modality that relies on the delivery of acoustic energy to remote tissue sites to induce thermal and/or…”
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6
Fully nonlinear three-dimensional modeling of parametric interactions in the field of a dual-frequency acoustic array
Published in The Journal of the Acoustical Society of America (01-03-2024)“…An algorithm is developed for fully nonlinear three-dimensional (3D) simulation of a difference-frequency acoustic beam resulting from the interaction of two…”
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7
"HIFU Beam:" A Simulator for Predicting Axially Symmetric Nonlinear Acoustic Fields Generated by Focused Transducers in a Layered Medium
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-09-2021)“…"HIFU beam" is a freely available software tool that comprises a MATLAB toolbox combined with a user-friendly interface and binary executable compiled from…”
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8
Quantitative Assessment of Boiling Histotripsy Progression Based on Color Doppler Measurements
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-12-2022)“…Boiling histotripsy (BH) is a mechanical tissue liquefaction method that uses sequences of millisecond-long high intensity focused ultrasound (HIFU) pulses…”
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9
Partial Respiratory Motion Compensation for Abdominal Extracorporeal Boiling Histotripsy Treatments with a Robotic Arm
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-09-2021)“…Extracorporeal boiling histotripsy (BH), a noninvasive method for mechanical tissue disintegration, is getting closer to clinical applications. However, motion…”
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Introduction to the Special Issue on Histotripsy: Approaches, Mechanisms, Hardware, and Applications
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-09-2021)“…Histotripsy is a therapeutic ultrasound technology to liquefy tissue into acellular debris using sequences of high-power focused ultrasound pulses. Research on…”
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11
Histotripsy methods in mechanical disintegration of tissue: towards clinical applications
Published in International journal of hyperthermia (01-03-2015)“…In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within the body to locally affect the targeted site without damaging…”
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Ultrasound-guided tissue fractionation by high intensity focused ultrasound in an in vivo porcine liver model
Published in Proceedings of the National Academy of Sciences - PNAS (03-06-2014)“…The clinical use of high intensity focused ultrasound (HIFU) therapy for noninvasive tissue ablation has been recently gaining momentum. In HIFU, ultrasound…”
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13
Dynamic mode decomposition based Doppler monitoring of de novo cavitation induced by pulsed HIFU: an in vivo feasibility study
Published in Scientific reports (27-09-2024)“…Pulsed high-intensity focused ultrasound (pHIFU) has the capability to induce de novo cavitation bubbles, offering potential applications for enhancing drug…”
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14
Comparative Characterization of Nonlinear Ultrasound Fields Generated by Sonalleve V1 and V2 MR-HIFU Systems
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-06-2023)“…A Sonalleve magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) clinical system (Profound Medical, Canada) has been shown to generate…”
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15
Design of HIFU Transducers for Generating Specified Nonlinear Ultrasound Fields
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-02-2017)“…Various clinical applications of high-intensity focused ultrasound have different requirements for the pressure levels and degree of nonlinear waveform…”
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16
Irregular reflection of spark-generated shock pulses from a rigid surface: Mach-Zehnder interferometry measurements in air
Published in The Journal of the Acoustical Society of America (01-01-2019)“…The irregular reflection of weak acoustic shock waves, known as the von Neumann reflection, has been observed experimentally and numerically for spherically…”
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Effect of surface roughness on nonlinear reflection of weak shock waves
Published in The Journal of the Acoustical Society of America (01-11-2019)“…The authors have recently shown that irregular reflections of spark-generated pressure weak shocks from a smooth rigid surface can be studied using an optical…”
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18
The histotripsy spectrum: differences and similarities in techniques and instrumentation
Published in International journal of hyperthermia (2023)“…Since its inception about two decades ago, histotripsy - a non-thermal mechanical tissue ablation technique - has evolved into a spectrum of methods, each with…”
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Acoustic characterization of high intensity focused ultrasound fields: A combined measurement and modeling approach
Published in The Journal of the Acoustical Society of America (01-10-2008)“…Acoustic characterization of high intensity focused ultrasound (HIFU) fields is important both for the accurate prediction of ultrasound induced bioeffects in…”
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20
Mach stem formation in reflection and focusing of weak shock acoustic pulses
Published in The Journal of the Acoustical Society of America (01-06-2015)“…The aim of this study is to show the evidence of Mach stem formation for very weak shock waves with acoustic Mach numbers on the order of 10(-3) to 10(-2). Two…”
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