Search Results - "Khokha, R"

MiR-26a inhibits stem cell-like phenotype and tumor growth of osteosarcoma by targeting Jagged1 by Lu, J, Song, G, Tang, Q, Yin, J, Zou, C, Zhao, Z, Xie, X, Xu, H, Huang, G, Wang, J, Lee, D-F, Khokha, R, Yang, H, Shen, J

“…MicroRNAs (miRNAs) are important epigenetic regulators of gene expression. Although several miRNAs have been implicated in osteosarcoma, their role in…”
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TIMP3 controls cell fate to confer hepatocellular carcinoma resistance by Defamie, V, Sanchez, O, Murthy, A, Khokha, R

“…Inflammation enables human cancers and is a critical promoter of hepatocellular carcinoma (HCC). TIMP3 (Tissue inhibitor of metalloproteinase 3), a natural…”
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DIAGNOSTICS OF ALLERGIES: REALITIES AND PROSPECTS. PART 1 by Khokha, R. N.

“…The results of epidemiological studies indicate an increase in the prevalence of allergic diseases. The identifcation of causative allergens is crucial for…”
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FEATURES OF PHYSICAL DEVELOPMENT OF CHILDREN WITH BRONCHIAL ASTHMA. DYNAMIC TENDENCIES by Khokha, R. N.

“…Вackground. Physical development is one of the leading indicators of a child’s health, and in the case of bronchial asthma, it can be a predictor of the…”
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SENSITIZATION OF CHILDREN WITH BRONCHIAL ASTHMA. ANALYSIS OF 10-YEAR DYNAMICS by Khokha, R. N.

“…Вackground. Sensitization to allergens is a major factor contributing to the development of bronchial asthma, maintenance of its symptoms and risk of its…”
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PKA signaling drives mammary tumorigenesis through Src by Beristain, A G, Molyneux, S D, Joshi, P A, Pomroy, N C, Di Grappa, M A, Chang, M C, Kirschner, L S, Privé, G G, Pujana, M A, Khokha, R

“…Protein kinase A (PKA) hyperactivation causes hereditary endocrine neoplasias; however, its role in sporadic epithelial cancers is unknown. Here, we show that…”
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GEOGRAPHICAL FEATURES OF ATOPIC DERMATITIS INCIDENCE IN THE CHILD POPULATION OF THE GRODNO REGION by Khokha, R. N.

“…Research objective. To estimate a geographical variation of the indicator of the incidence of atopic dermatitis among the child population of the Grodno…”
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Molecular mechanisms of tumor invasion and metastasis: an integrated view by Cairns, R A, Khokha, R, Hill, R P

“…As tumors progress to increased malignancy, cells within them develop the ability to invade into surrounding normal tissues and through tissue boundaries to…”
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Matrix metalloproteinases and their tissue inhibitors direct cell fate during cancer development by HOJILLA, C. V, MOHAMMED, F. F, KHOKHA, R

“…Matrix metalloproteinases (MMPs) were initially recognised for their extracellular matrix (ECM)-degrading capability during tissue remodelling. Their…”
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Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation by JONES, R. A, CAMPBELL, C. I, GUNTHER, E. J, CHODOSH, L. A, PETRIK, J. J, KHOKHA, R, MOOREHEAD, R. A

“…Overexpression and hyperactivation of the type I insulin-like growth factor receptor (IGF-IR) has been observed in human breast tumor biopsies. In addition, in…”
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Suppression of the tumorigenic and metastatic abilities of murine B16-F10 melanoma cells in vivo by the overexpression of the tissue inhibitor of the metalloproteinases-1 by Khokha, R

“…Metalloproteinases participate in the first steps of tumor invasion and subsequent metastasis. Three distinct proteins have been identified as tissue…”
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Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell death following mild ischemia by Wetzel, M, Li, L, Harms, K M, Roitbak, T, Ventura, P B, Rosenberg, G A, Khokha, R, Cunningham, L A

“…Tissue inhibitor of metalloproteinase-3 (TIMP-3) is a natural inhibitor of metalloproteinases involved in matrix degradation and ectodomain shedding of many…”
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BRONCHIAL ASTHMA IN CHILDREN: IS IT POSSIBLE TO PREVENT THE DISEASE? by Paramonova, N. S., Khokha, R. N., Harbacheuski, P. R.

“…Background. Bronchial asthma is one of the most common chronic diseases of the respiratory system, significantly impairing the quality of patients’ life…”
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Cellular turnover in the mammary gland is correlated with systemic levels of progesterone and not 17β-estradiol during the estrous cycle by FATA, Jimmie E, CHAUDHARY, Varun, KHOKHA, Rama

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TIMP-3 deficiency in the host, but not in the tumor, enhances tumor growth and angiogenesis by CRUZ-MUNOZ, W, KIM, I, KHOKHA, R

“…Tumor cells, stromal cell compartment and the extracellular matrix (ECM) together generate a multifaceted tumor microenvironment. Matrix metalloproteinases and…”
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The level of specific IgE and patterns of sensitization to the components of the house dust mite allergen Der p 1 and Der p 2 in children with bronchial asthma by Khokha, R N, Paramonova, N S, Zavodnik, L B

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Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3) by Leco, K J, Waterhouse, P, Sanchez, O H, Gowing, K L, Poole, A R, Wakeham, A, Mak, T W, Khokha, R

“…Tissue inhibitors of metalloproteinases regulate ECM degradation by matrix metalloproteinases (MMPs). We have developed a mouse line deficient for tissue…”
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Expression and Prognostic Significance of Metalloproteinases and Their Tissue Inhibitors in Patients With Small-Cell Lung Cancer by MICHAEL, M, BABIC, B, KHOKHA, R, TSAO, M, HO, J, PINTILIE, M, LECO, K, CHAMBERLAIN, D, SHEPHERD, F. A

“…Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are important in tumor development and progression. MMP expression has been correlated…”
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Cytokine stimulated vascular cell adhesion molecule-1 (VCAM-1) ectodomain release is regulated by TIMP-3 by SINGH, Robert J. R, MASON, Justin C, LIDINGTON, Elaine A, EDWARDS, Dylan R, NUTTALL, Robert K, KHOKHA, Rama, KNAUPER, Vera, MURPHY, Gillian, GAVRILOVIC, Jelena

“…Vascular cell adhesion molecule-1 (VCAM-1) is a cell surface adhesion molecule involved in the recruitment of leukocytes to endothelial cells on arterial walls…”
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FOREIGN BODY OF THE ESOPHAGUS IN CHILDREN: A CASE STUDY by Khokha, R. N., Krivetsky, D. S., Vezhel, O. V., Nasridinova, V. A., Isaenko, K. V.

“…The case of a child aged 1.5 years with a foreign body of the esophagus, whose diagnosis was hampered by a combined manifestation of 2 clinical syndromes –…”
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