Search Results - "Khojasteh, Mehrnoush"

A stepwise framework for the normalization of array CGH data by Khojasteh, Mehrnoush, Lam, Wan L, Ward, Rabab K, MacAulay, Calum

“…In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is…”
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Abstract 4030: Case classification with tumor antigen presenting and TGF-β signaling biomarkers to predict anti-PD-1 outcome in GI tract tumors using automated quantitative fluorescence multiplex IHC by Wang, Xiangxue, Moh, Shizen, Hubbard, Antony, Muñoz-Rodríguez, José L., Khojasteh, Mehrnoush, Martin, Jim, Zhu, Qingfeng, Anders, Robert, Diaz, Luis, Pestic-Dragovich, Lidija, Tang, Lei, Zhang, Wenjun

“…Abstract Introduction: Anti-PD-1/L1 immune checkpoint blockade results in tumor stabilization or shrinkage in only 15-40% of patients. Predictive biomarkers…”
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Abstract P1-02-17: Artificial intelligence-based whole slide scoring of nuclear breast cancer IHC markers Ki67, ER, and PR matches performance of manual clinical scoring by Kapadia, Monesh, Khojasteh, Mehrnoush, Kouzova, Margarita, Jones, Carol, Xu, Xiao-Meng, Olson, Matthew T., Gladden, Sarah, Sapanara, Nancy, Singh, Shalini, Chen, Chen Chun, Bai, Isaac, Ranger-Moore, Jim, Inge, Landon J., Kurkure, Uday, Bhattacharya, Ipshita, Zhao, Margaret, Zuiderveld, Karel, Chintakindi, Chandana, Lopez, Bryan, Guetter, Christoph

“…Abstract Background: 2.1 million breast cancers are newly diagnosed each year. Current guidelines endorse routine testing for estrogen receptor (ER) and…”
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Abstract A28: Improving detection through SELF (selective excitation light fluorescence) imaging by MacAulay, Calum, Khojasteh, Mehrnoush

“…Abstract The use of fluorescence imaging and spectroscopy for the detection of early neoplastic epithelial lesions has been well established, with clinically…”
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Integrating copy number polymorphisms into array CGH analysis using a robust HMM by Shah, Sohrab P., Xuan, Xiang, DeLeeuw, Ron J., Khojasteh, Mehrnoush, Lam, Wan L., Ng, Raymond, Murphy, Kevin P.

“…Motivation: Array comparative genomic hybridization (aCGH) is a pervasive technique used to identify chromosomal aberrations in human diseases, including…”
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Abstract 5117: An automated 5-plex fluorescent immunohistochemistry enabled characterization of PD-L1 expression and tumor infiltrating immune cells in lung and bladder cancer specimens by Zhang, Wenjun, Hubbard, Antony, Racolta, Adriana, Cummins, Nick, Khojasteh, Mehrnoush, Zhang, Liping, Garsha, Karl, Bredno, Joerg, Harshman, Dustin, Bhaumik, Srabani, Jones, Tobin, Kowanetz, Marcin, Mariathasan, Sanjeev, McCaffery, Ian, Smith, Dustin, Williams, J Andrew, Pestic-Dragovich, Lidija, Morrison, Larry, Tang, Lei

“…Abstract Cancers may escape immune surveillance and eradication through the expression of programmed death-ligand 1 (PD-L1) on tumor cells and in the tumor…”
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Quantitative image analysis of PD-L1, CD8, CD3, CD68 and FoxP3 protein expression in lung and bladder cancer specimens by fully automated multiplex fluorescence immunohistochemistry by Zhang, Wenjun, Khojasteh, Mehrnoush, Cummins, Nick, Hubbard, Antony, Hurley, John, Zhang, Liping, Elgabry, Ehab, Bredno, Joerg, Harshman, Dustin, Day, William, Kowanetz, Marcin, Mariathasan, Sanjeev, Smith, Dustin, Williams, J. Andrew, Pestic-Dragovich, Lidija, Morrison, Larry E., Tang, Lei

“…Abstract only…”
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Automated imaging and analysis of hematopoietic CFU assays of mouse bone marrow by Khojasteh, Mehrnoush, Walasek, Marta A, Wognum, Albertus W, Szilvassy, Stephen J, Egeler, Oliver, Woodside, Steven, Poon, Steven, Thomas, Terry, Eaves, Allen

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Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group by Amgad, Mohamed, Stovgaard, Elisabeth Specht, Balslev, Eva, Thagaard, Jeppe, Chen, Weijie, Dudgeon, Sarah, Sharma, Ashish, Kerner, Jennifer K, Denkert, Carsten, Yuan, Yinyin, AbdulJabbar, Khalid, Wienert, Stephan, Savas, Peter, Voorwerk, Leonie, Beck, Andrew H, Madabhushi, Anant, Hartman, Johan, Sebastian, Manu M, Horlings, Hugo M, Hudeček, Jan, Ciompi, Francesco, Moore, David A, Singh, Rajendra, Roblin, Elvire, Balancin, Marcelo Luiz, Mathieu, Marie-Christine, Lennerz, Jochen K, Kirtani, Pawan, Chen, I-Chun, Braybrooke, Jeremy P, Pruneri, Giancarlo, Demaria, Sandra, Adams, Sylvia, Schnitt, Stuart J, Lakhani, Sunil R, Rojo, Federico, Comerma, Laura, Badve, Sunil S, Khojasteh, Mehrnoush, Symmans, W Fraser, Sotiriou, Christos, Gonzalez-Ericsson, Paula, Pogue-Geile, Katherine L, Kim, Rim S, Rimm, David L, Viale, Giuseppe, Hewitt, Stephen M, Bartlett, John M S, Penault-Llorca, Frédérique, Goel, Shom, Lien, Huang-Chun, Loibl, Sibylle, Kos, Zuzana, Loi, Sherene, Hanna, Matthew G, Michiels, Stefan, Kok, Marleen, Nielsen, Torsten O, Lazar, Alexander J, Bago-Horvath, Zsuzsanna, Kooreman, Loes F S, van der Laak, Jeroen A W M, Saltz, Joel, Gallas, Brandon D, Kurkure, Uday, Barnes, Michael, Salgado, Roberto, Cooper, Lee A D

“…Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral part of the prognostic workflow in triple-negative (TNBC) and…”
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A framework for quantitative assessment of Ki67 distribution in preneoplastic bronchial epithelial lesions by Khojasteh, Mehrnoush, Buys, Timon P H, LeRiche, Jean, Lam, Stephen, Guillaud, Martial, MacAulay, Calum

“…Deregulated cell proliferation is a hallmark of cancer, and Ki67 immunostaining can be used to identify proliferating cells. Evaluation of cell proliferation…”
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Quantification of membrane IHC stains through multi-spectral imaging by Khojasteh, M., Ward, R., MacAulay, C.

“…This work presents a fully automated approach to the quantification of the expression of antibodies in immunohistochemically stained tissue sections…”
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Abstract A18: Spatial dynamics of cellular proliferation in preneoplastic lesions: Comparison between bronchial, oral, and cervical epithelium by Guillaud, Martial D., van Niekerk, Dirk, Khojasteh, Mehrnoush, Carraro, Anita, Korbelik, Jagoda, Frung, Priscilla, Kamalov, Rassim, Rosin, Miriam P., Follen, Michele, Lam, Stephen, MacAulay, Calum

“…Abstract Introduction: Uncontrolled proliferation is a hallmark of cancer and a biologically plausible risk biomarker for preneoplastic epithelium. The…”
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