Search Results - "Khodyreva, S. N."

The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context by Kutuzov, M. M., Belousova, E. A., Kurgina, T. A., Ukraintsev, A. A., Vasil’eva, I. A., Khodyreva, S. N., Lavrik, O. I.

“…The regulation of repair processes including base excision repair (BER) in the presence of DNA damage is implemented by a cellular signal:…”
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Apurinic/apyrimidinic (AP) site recognition by the 5'-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1) by Khodyreva, S. N., Prasad, R., Ilina, E. S., Sukhanova, M. V., Kutuzov, M. M., Liu, Y., Hou, E. W., Wilson, S. H., Lavrik, O. I., Hanawalt, Philip C.

“…The capacity of human poly(ADP-ribose) polymerase-1 (PARP-1) to interact with intact apurinic/apyrimidinic (AP) sites in DNA has been demonstrated. In cell…”
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Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in DNA repair by Kosova, A. A., Khodyreva, S. N., Lavrik, O. I.

“…Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is widely known as a glycolytic enzyme. Nevertheless, various functions of GAPDH have been found that are…”
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Interaction of poly(ADP-ribose) polymerase 1 with apurinic/apyrimidinic sites within clustered DNA damage by Kutuzov, M. M, Ilina, E. S, Sukhanova, M. V, Pyshnaya, I. A, Pyshnyi, D. V, Lavrik, O. I, Khodyreva, S. N

“…To study the interaction of poly(ADP-ribose) polymerase 1 (PARP1) with apurinic/apyrimidinic sites (AP sites) within clustered damages, DNA duplexes were…”
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Affinity modification in a proteomic study of DNA repair ensembles by Khodyreva, S. N, Lavrik, O. I

“…This review concerns the use of the affinity modification method as a component of modern proteomic analysis in the search and identification of proteins…”
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5'-Deoxyribose Phosphate Lyase Activity of Apurinic/Apyrimidinic Endonuclease 1 by Ilina, E. S., Lavrik, O. I., Khodyreva, S. N.

“…One of the most common DNA lesions is the appearance of apurinic/apyrimidinic (AP-) sites. The main repair pathway for AP sites is initiated by…”
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Influence of the Poly(ADP-Ribose) Polymerase 1 Level on the Status of Base Excision Repair in Human Cells by Ilina, E. S., Kochetkova, A. S., Belousova, E. A., Kutuzov, M. M., Lavrik, O. I., Khodyreva, S. N.

“…Base excision repair (BER) is aimed at repair of damaged bases, which are the largest group of DNA lesions. The main steps of BER are recognition and removal…”
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Poly(ADP-Ribose) polymerase 1 as a key regulator of DNA repair by Khodyreva, S. N., Lavrik, O. I.

“…Poly(ADP-ribosyl)ation (PARylation) of proteins is one of the immediate cell responses to DNA damage and is catalyzed by poly(ADP-ribose) polymerases (PARPs)…”
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Influence of the Poly(ADP-Ribose) Polymerase 1 Level on the Status of Base Excision Repair in Human Cells by Ilina, E S, Kochetkova, A S, Belousova, E A, Kutuzov, M M, Lavrik, O I, Khodyreva, S N

“…Base excision repair (BER) is aimed at repair of damaged bases, which are the largest group of DNA lesions. The main steps of BER are recognition and removal…”
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RPA subunit arrangement near the 3′-end of the primer is modulated by the length of the template strand and cooperative protein interactions by Lavrik, Olga I., Kolpashchikov, Dmitry M., Weisshart, Klaus, Nasheuer, Heinz-Peter, Khodyreva, Svetlana N., Favre, Alain

“…To analyze the interaction of human replication protein A (RPA) and its subunits with the DNA template-primer junction in the DNA replication fork, we designed…”
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Poly(ADP-ribose) polymerase-1 inhibits strand-displacement synthesis of DNA catalyzed by DNA polymerase beta by Sukhanova, M V, Khodyreva, S N, Lavrik, O I

“…Poly(ADP-ribose) polymerase-1 (PARP-1), a eucaryotic nuclear DNA-binding protein that is activated by breaks in DNA chains, may be involved in the base…”
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Triazinylamidophosphate Oligonucleotides: Synthesis and Study of Their Interaction with Cells and DNA-Binding Proteins by Kupryushkin, M. S., Zharkov, T. D., Ilina, E. S., Markov, O. V., Kochetkova, A. S., Akhmetova, M. M., Lomzov, A. A., Pyshnyi, D. V., Lavrik, O. I., Khodyreva, S. N.

“…In this work, representatives of the class of triazinylamidophosphate oligonucleotide derivatives were obtained for the first time. A scheme for the…”
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Optimization of nucleosome assembly from histones and model DNAs and estimation of the reconstitution efficiency by Kutuzov, M. M., Kurgina, T. A., Belousova, E. A., Khodyreva, S. N., Lavrik, O. I.

“…Nucleosome core particles (NCPs) are basic units of chromatin organization; they represent the most convenient model system for the study of key DNA-dependent…”
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3'-5' exonuclease activity of human apurinic/apyrimidinic endonuclease 1 towards DNAs containing dNMP and their modified analogs at the 3 end of single strand DNA break by Dyrkheeva, N S, Khodyreva, S N, Sukhanova, M V, Safronov, I V, Dezhurov, S V, Lavrik, O I

“…Human DNA apurinic/apyrimidinic (AP-) endonuclease 1 (APE1) is involved in the base excision repair (BER) pathway. The enzyme hydrolyzes DNA from the 5 side of…”
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Ku80 interaction with apurinic/apyrimidinic sites depends on the structure of DNA ends by Kosova, A. A., Khodyreva, S. N., Lavrik, O. I.

“…Aim. The identification of a protein from human cell extract which specifically interacts with the apurinic/apyrimidinic (AP) site in the partial DNA duplex…”
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Role of PARP2 in DNA repair by Kutuzov, M. M., Khodyreva, S. N., Schreiber, V., Lavrik, O. I.

“…The genome stability of higher eukaryotes depends largely on the functioning of the DNA repair systems. In turn, the precise regulation of each step of repair…”
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Interaction of the p70 subunit of RPA with a DNA template directs p32 to the 3′-end of nascent DNA by Kolpashchikov, D.M., Weisshart, K., Nasheuer, H.-P., Khodyreva, S.N., Fanning, E., Favre, A., Lavrik, O.I.

“…Human replication protein A is a heterotrimeric protein involved in various processes of DNA metabolism. To understand the contribution of replication protein…”
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Role of Ku antigen in the repair of apurinic/apyrimidinic sites in DNA by Kosova, A. A., Lavrik, O. I., Khodyreva, S. N.

“…Apurinic/apyrimidinic (AP) sites are some of the most frequent lesions in genomic DNA. It is widely accepted that, regardless of their origin, AP sites are…”
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Interaction of flap endonuclease-1 and replication protein A with photoreactive intermediates of DNA repair by Nazarkina, J K, Petrousseva, I O, Safronov, I V, Lavrik, O I, Khodyreva, S N

“…A new method for enzymatic synthesis of radioactive DNA flapped structures containing a photoreactive dCMP moiety at a branch point with…”
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Use of modified flap structures for study of base excision repair proteins by Nazarkina, Zh K, Pyshnyi, D V, Pyshnaya, I A, Lavrik, O I, Khodyreva, S N

“…To investigate interactions between proteins participating in the long-patch pathway of base excision repair (BER), DNA duplexes with flap strand containing…”
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