Search Results - "Khodorov, Boris I."

Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures by Surin, Alexander M, Khiroug, Serguei, Gorbacheva, Lubov R, Khodorov, Boris I, Pinelis, Vsevolod G, Khiroug, Leonard

“…ATP in neurons is commonly believed to be synthesized mostly by mitochondria via oxidative phosphorylation. Neuronal mitochondria have been studied primarily…”
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Glutamate-induced mitochondrial depolarisation and perturbation of calcium homeostasis in cultured rat hippocampal neurones by Vergun, Olga, Keelan, Julie, Khodorov, Boris I., Duchen, Michael R.

“…The objective of this study was to clarify the relationships between loss of mitochondrial potential and the perturbation of neuronal Ca 2+ homeostasis induced…”
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Measurements of mitochondrial pH in cultured cortical neurons clarify contribution of mitochondrial pore to the mechanism of glutamate-induced delayed Ca2+ deregulation by Bolshakov, Alexey P, Mikhailova, Maria M, Szabadkai, György, Pinelis, Vsevolod G, Brustovetsky, Nickolay, Rizzuto, Rosario, Khodorov, Boris I

“…Abstract To clarify the role of the mitochondrial permeability transition pore (MPT) in the mechanism of the glutamate-induced delayed calcium deregulation…”
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Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture by Vergun, Olga, Sobolevsky, Alexander I., Yelshansky, Maria V., Keelan, Julie, Khodorov, Boris I., Duchen, Michael R.

“…Exposure of hippocampal neurones to glutamate at toxic levels is associated with a profound collapse of mitochondrial potential and deregulation of calcium…”
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Interaction of memantine and amantadine with agonist-unbound NMDA-receptor channels in acutely isolated rat hippocampal neurons by Sobolevsky, Alexander I., Koshelev, Sergey G., Khodorov, Boris I.

“…Using whole-cell patch-clamp techniques, the mechanisms of NMDA channel blockade by amino-adamantane derivatives (AADs) memantine…”
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Mitochondrial Ca2+ cycle mediated by the palmitate-activated cyclosporin A-insensitive pore by Mironova, Galina D, Belosludtsev, Konstantin N, Belosludtseva, Natalia V, Gritsenko, Elena N, Khodorov, Boris I, Saris, Nils-Erik L

“…Earlier we found that in isolated rat liver mitochondria the reversible opening of the mitochondrial cyclosporin A-insensitive pore induced by low…”
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Probing of NMDA Channels with Fast Blockers by Sobolevsky, Alexander I, Koshelev, Sergey G, Khodorov, Boris I

“…Using whole-cell patch-clamp techniques, we studied the interaction of open NMDA channels with tetraalkylammonium compounds: tetraethylammonium (TEA),…”
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Blockade of NMDA channels in acutely isolated rat hippocampal neurons by the Na+/Ca2+ exchange inhibitor KB-R7943 by SOBOLEVSKY, A. I, KHODOROV, B. I

“…Neurons acutely isolated from the CA1 region of rat hippocampal slices using the 'vibrodissociation' method were voltage-clamped in the whole-cell…”
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Role of Ca 2+/H + Exchange and Disturbance of Oxidative Phosphorilation in Glutamate-Induced Delayed Calcium Deregulation in Cultured Neurons by Pinelis, Vsevolod G., Surin, Alexander M., Khiroug, Leo S., Krasilnikova, Irina A., Rozhnev, Sergej V., Khodorov, Boris I.

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Store-operated Orai1 and IP3 receptor-operated TRPC1 channel by Zarayskiy, Vladislav, Monje, Francisco, Peter, Krisztina, Csutora, Peter, Khodorov, Boris I, Bolotina, Victoria M

“…Store-operated channels (SOC) are known to be physiologically activated following agonist-induced IP3 production and depletion of Ca2+ stores. Here we present…”
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Measurements of mitochondrial pH in cultured cortical neurons clarify contribution of mitochondrial pore to the mechanism of glutamate-induced delayed Ca 2+ deregulation by Bolshakov, Alexey P., Mikhailova, Maria M., Szabadkai, György, Pinelis, Vsevolod G., Brustovetsky, Nickolay, Rizzuto, Rosario, Khodorov, Boris I.

“…To clarify the role of the mitochondrial permeability transition pore (MPT) in the mechanism of the glutamate-induced delayed calcium deregulation (DCD) and…”
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Store-Operated Orai1 and IP3 Receptor-Operated TRPC1 Channel: Separation of the Siamese Twins by Zarayskiy, Vladislav V., Monje, Francisco, Peter, Krisztina, Csutora, Peter, Khodorov, Boris, Bolotina, Victoria M.

“…Store-operated channels (SOC) are known to be physiologically activated following agonist-induced IP 3 production and depletion of Ca 2+ stores. Here we…”
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Mitochondrial Ca super(2+) cycle mediated by the palmitate-activated cyclosporin a-insensitive pore by Mironova, Galina D, Belosludtsev, Konstantin N, Belosludtseva, Natalia V, Gritsenko, Elena N, Khodorov, Boris I, Saris, Nils-Erik L

“…Earlier we found that in isolated rat liver mitochondria the reversible opening of the mitochondrial cyclosporin A-insensitive pore induced by low…”
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Blockade of NMDA channels in acutely isolated rat hippocampal neurons by the Na +/Ca 2+ exchange inhibitor KB-R7943 by Sobolevsky, Alexander I., Khodorov, Boris I.

“…Neurons acutely isolated from the CA1 region of rat hippocampal slices using the ‘vibrodissociation’ method were voltage-clamped in the whole-cell…”
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Eosine-induced blockade of N-methyl-D-aspartate channels in acutely isolated rat hippocampal neurons by Sobolevsky, A I, Yelshansky, M V, Khodorov, B I

“…Acutely isolated rat hippocampal neurons were voltage-clamped in the whole-cell configuration. The currents through N-methyl-D-aspartate (NMDA) channels were…”
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Effect of a prolonged glutamate challenge on plasmalemmal calcium permeability in mammalian central neurones. Mn2+ as a tool to study calcium influx pathways by Khodorov, B I, Fayuk, D A, Koshelev, S G, Vergun, O V, Pinelis, V G, Vinskaya, N P, Storozhevykh, T P, Arsenyeva, E N, Khaspekov, L G, Lyzhin, A P, Isaev, N, Victorov, I V, Dubinsky, J M

“…The rate of Mn(2+)-induced fluorescence quenching (RFQ) was used as a relative measure of plasma membrane Ca2+ permeability (PCa) in fura-2-loaded cultured…”
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Bepridil exacerbates glutamate-induced deterioration of calcium homeostasis and cultured nerve cell injury by Storozhevykh, T P, Sorokina, E G, Vinskaya, N P, Pinelis, V G, Vergun, O V, Fayuk, D A, Sobolevskiy, A I, Khodorov, B I

“…Application of 50 microM bepridil (BPD) to cultured nerve cells did not greatly affect the resting cytoplasmic Ca2+ concentration ([Ca2+]i) but caused its…”
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Comparative analysis of the effects of synthetic derivatives of batrachotoxin on sodium currents in frog node of Ranvier by KHODOROV, B. I, YELIN, E. A, ZABOROVSKAYA, L. D, MAKSUDOV, M. Z, TIKHOMIROVA, O. B, LEONOV, V. N

“…1. In voltage-clamp experiments on frog myelinated nerve fibers, the effects of nine synthetic derivatives of batrachotoxin (BTX) obtained from…”
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Voltage dependence of intramembrane charge movement and conductance activation of batrachotoxin-modified sodium channels in frog node of Ranvier by Dubois, J M, Schneider, M F, Khodorov, B I

“…Sodium current and sodium channel intramembrane gating charge movement (Q) were monitored in voltage-clamped frog node of Ranvier after modification of all…”
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Properties of different Ca 2+ pools in permeabilized rat thymocytes by GUKOVSKAYA, Anna S., ZINCHENKO, Valery P., PETRUNYAKA, Victor V., KHODOROV, Boris I., EVTODIENKO, Yury V.

“…The regulation of free Ca 2+ concentration by intracellular pools and their participation in the mitogen‐induced changes of the cytosolic free Ca 2+…”
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