Search Results - "Khodorov, B I"

Study on ATP concentration changes in cytosol of individual cultured neurons during glutamate-induced deregulation of calcium homeostasis by Surin, A. M., Gorbacheva, L. R., Savinkova, I. G., Sharipov, R. R., Khodorov, B. I., Pinelis, V. G.

“…For the first time, simultaneous monitoring of changes in the concentration of cytosolic ATP ([ATP] c ), pH (pH c ), and intracellular free Ca 2+ concentration…”
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Blockade of NMDA channels in acutely isolated rat hippocampal neurons by the Na+/Ca2+ exchange inhibitor KB-R7943 by SOBOLEVSKY, A. I, KHODOROV, B. I

“…Neurons acutely isolated from the CA1 region of rat hippocampal slices using the 'vibrodissociation' method were voltage-clamped in the whole-cell…”
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Batrachotoxin as a tool to study voltage-sensitive sodium channels of excitable membranes by Khodorov, B I

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Mathematical modelling of delayed calcium deregulation in brain neurons caused by hyperstimulation of glutamate receptors by Chastukhin, D S, Borodin, A V, Khodorov, B I

“…Mathematical model presented in this paper is based on the data obtained in experimental studies of the mechanism of glutamate-induced deregulation of Ca2+…”
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Bepridil-induced Blockade of NMDA Channels in Rat Hippocampal Neurones by SOBOLEVSKY, A, KOSHELEV, S, KHODOROV, B.I

“…Neurones isolated from the CA1 region of rat hippocampal slices by the “vibrodissociation” method were voltage-clamped in the whole-cell configuration. The…”
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Glutamate-induced mitochondrial depolarisation and perturbation of calcium homeostasis in cultured rat hippocampal neurones by Vergun, Olga, Keelan, Julie, Khodorov, Boris I., Duchen, Michael R.

“…The objective of this study was to clarify the relationships between loss of mitochondrial potential and the perturbation of neuronal Ca 2+ homeostasis induced…”
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Role of inactivation in local anesthetic action by Khodorov, B I

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Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture by Vergun, Olga, Sobolevsky, Alexander I., Yelshansky, Maria V., Keelan, Julie, Khodorov, Boris I., Duchen, Michael R.

“…Exposure of hippocampal neurones to glutamate at toxic levels is associated with a profound collapse of mitochondrial potential and deregulation of calcium…”
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Dramatic effect of glycolysis inhibition on the cerebellar granule cells bioenergetics by Khodorov, B. I., Mikhailova, M. M., Bolshakov, A. P., Surin, A. M., Sorokina, E. G., Rozhnev, S. A., Pinelis, V. G.

“…Cultured cerebellar granule cells were co-loaded with Ca 2+ -sensitive dye fura-2FF and rhodamine-123 sensitive to changes in the mitochondrial potential (ΔΨ m…”
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Mitochondrial lipid pore in the mechanism of glutamate-induced calcium deregulation of brain neurons by Mironova, G. D., Belosludtsev, K. N., Surin, A. M., Trudovishnikov, A. S., Belosludtseva, N. V., Pinelis, V. G., Krasilnikova, I. A., Khodorov, B. I.

“…The work examines the mechanism of central nerve cell death upon stimulation of brain NMDA receptors with the stimulatory mediator glutamate. A prolonged…”
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Effects of repetitive stimulation, veratridine and ouabain on cytoplasmic pH in frog nerve fibres: role of internal Na by Valkina, O.N., Vergun, O.V., Turovetsky, V.B., Khodorov, B.I.

“…Changes of cytoplasmic pH (pH i) in frog nerve fibres during repetitive stimulation have been measured using the fluorescent pH indicator dye fluorescein…”
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Synaptic mechanisms of use-dependent potentiation and use-dependent inhibition of evoked burst discharges in rat hippocampal slices by Kalashnikova, N. V., Motin, V. G., Khodorov, B. I.

“…The mechanisms of activity-dependent modulation of burst discharges in rat hippocampal slices have been studied. The extracellular registration of field…”
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Probing of NMDA Channels with Fast Blockers by Sobolevsky, Alexander I, Koshelev, Sergey G, Khodorov, Boris I

“…Using whole-cell patch-clamp techniques, we studied the interaction of open NMDA channels with tetraalkylammonium compounds: tetraethylammonium (TEA),…”
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Changes in mitochondrial NAD(P)H and glutamate-induced delayed calcium deregulation in cultured rat cerebellar granule neurons by Surin, A. M., Zobova, S. N., Tukhbatova, G. R., Senilova, Y. E., Pinelis, V. G., Khodorov, B. I.

“…Changes in cytosolic [Ca 2+ ] i , mitochondrial potential (ΔVm), and mitochondrial NAD(P)H autofluorescence were compared in experiments on cultured cerebellar…”
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Evidence for pore opening in mitochondrial membrane during glutamate-induced delayed calcium deregulation in brain neurons by Surin, A. M., Pinelis, V. G., Vinogradov, A. D., Khodorov, B. I.

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Arachidonic acid enhances intracellular [Ca2+]i increase and mitochondrial depolarization induced by glutamate in cerebellar granule cells by Surin, A M, Bolshakov, A P, Mikhailova, M M, Sorokina, E G, Senilova, Ya E, Pinelis, V G, Khodorov, B I

“…Maturation of primary neuronal cultures is accompanied by an increase in the proportion of cells that exhibit biphasic increase in free cytoplasmic Ca2+…”
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Changes in ATP content in cerebellar granule cells during hyperstimulation of glutamate receptors: possible role of NO and nitrite ions by Sorokina, E G, Reutov, V P, Senilova, Ya E, Khodorov, B I, Pinelis, V G

“…In primary 7-8-day culture of cerebellar granule cells, glutamate exposure (100 microM, 10-240 min) induced a 60-30% drop in ATP level; during the…”
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Toxic effect of glutamate on granular cells of the cerebellum reduces cell ATP content. The role of calcium ions by Pinelis, V. G., Bykova, L. P., Bogachev, A. P., Isaev, N. K., Viktorov, I. V., Khodorov, B. I.

“…The content of ATP in cultured cerebellar granular cells during and after glutamate intoxication is determined using the luciferin-luciferase method. A 15-min…”
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Role of protein kinase C in Ca2+ homeostasis disorders in cultured rat neurons during hyperstimulation of glutamate receptors by Persiyantseva, N. A., Birikh, K. R., Dvoretskova, E. A., Pinelis, V. G., Khodorov, B. I.

“…The primary culture of rat cerebellar neurons was used to study protein kinase C activity, intracellular variations in calcium concentration ([Ca 2+ ] i ),…”
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Role of protein kinase C in Ca(2+) homeostasis disorders in cultured rat neurons during hyperstimulation of glutamate receptors by Persiyantseva, N A, Birikh, K R, Dvoretskova, E A, Pinelis, V G, Khodorov, B I

“…The primary culture of rat cerebellar neurons was used to study protein kinase C activity, intracellular variations in calcium concentration ([Ca(2+)]i),…”
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