Search Results - "Khochenkov, D. A."

Photodynamic therapy of melanoma by blue-light photoactivation of flavin mononucleotide by Akasov, R. A., Sholina, N. V., Khochenkov, D. A., Alova, A. V., Gorelkin, P. V., Erofeev, A. S., Generalova, A. N., Khaydukov, E. V.

“…Melanoma is one of the most aggressive and lethal form of cancer. Photodynamic therapy (PDT) is a clinically approved technique for cancer treatment, including…”
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Riboflavin photoactivation by upconversion nanoparticles for cancer treatment by Khaydukov, E. V., Mironova, K. E., Semchishen, V. A., Generalova, A. N., Nechaev, A. V., Khochenkov, D. A., Stepanova, E. V., Lebedev, O. I., Zvyagin, A. V., Deyev, S. M., Panchenko, V. Ya

“…Riboflavin (Rf) is a vitamin and endogenous photosensitizer capable to generate reactive oxygen species (ROS) under UV-blue irradiation and kill cancer cells,…”
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In vivo monitoring of vascularization and oxygenation of tumor xenografts using optoacoustic microscopy and diffuse optical spectroscopy by Akhmedzhanova, K G, Kurnikov, A A, Khochenkov, D A, Khochenkova, Yu A, Glyavina, A M, Kazakov, V V, Yudintsev, A V, Maslennikova, A V, Turchin, I V, Subochev, P V, Orlova, A G

“…The research is devoted to comparison of the blood vessel structure and the oxygen state of three xenografts: SN-12C, HCT-116 and Colo320. Differences in the…”
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3-Hydroxyquinazoline Derivatives, Analogues of Erastin, Induce Ferroptosis in Colorectal Cancer Cells by Osipov, V. N., Vartanyan, A. A., Khochenkov, D. A., Gusev, D. V., Fateenkova, O. V., Khachatryan, D. S., Borisova, L. M.

“…Objective: In recent years, significant progress has been achieved in the treatment of patients with colorectal cancer, but in most cases, treatment is…”
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Role of dendritic cells in the immune response to T-independent antigens of type 2 by Khochenkov, D. A.

“…Dendritic cells (DC) belong to the most effective antigen-presenting cells. Their role in the presentation of thymus-dependent antigens and initiation of…”
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1-Imidoyl-1,2,3-benzotriazoles—Novel Reagents for the Synthesis of 1-Aryl-5-trifluoromethylimidazoles by Bunev, A. S., Varakina, E. V., Khochenkov, D. A., Peregudov, A. S.

“…1-Imidoylbenzotriazoles [ N -aryl-1-(1 H -benzotriazol-1-yl)-2,2,2-trifluoroethan-1-imines] reacted with tosylmethyl isocyanide according to van Leusen’s…”
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Biology of dendritic cells by Khochenkov, D. A.

“…Dendritic cells (DC) play a key role in adaptive immune response. By virtue of their extremely wide distribution and high populational diversity, DC interact…”
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Advantages and Possibilities of Fluorescence-Based Methods for the Visualization of Apoptosis and Autophagy in Human Tumor Cells in vitro by Navolokin, N. A., Polukonova, N. V., Mudrak, D. A., Myl’nikov, A. M., Baryshnikova, M. A., Khochenkov, D. A., Bucharskaya, A. B., Polukonova, A. V., Maslyakova, G. N.

“…The possibilities of using fluorescence-based analytical methods and their advantages for visualization and identification of the type of programmed cell death…”
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Upconversion Nanoparticles Decorated with Polysialic Acid for Solid Tumors Visualization In Vivo by Demina, P. A., Sholina, N. V., Akasov, R. A., Khochenkov, D. A., Nechaev, A. V., Balalaeva, I. V., Khaydukov, E. V., Generalova, A. N., Deev, S. M.

“…Upconversion nanoparticles (UCNPs) are a promising nanoplatform for bioreagent formation for in vivo imaging, which emit UV and blue light under the action of…”
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Effect of Derivatives of Hydroxamic Acids on Vasculogenic Mimicry by Vartanian, A. A., Khochenkov, D. A., Khochenkova, Yu. A., Machkova, Yu. S., Khachatryan, D. S., Kolotaev, A. V., Balaev, A. N., Ohmanovich, K. A., Osipov, V. N.

“…— Vasculogenic mimicry, the formation of vascular channels lined with tumor cells of a highly malignant phenotype, is currently considered as an additional…”
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Nanosized Anti-Stokes Phosphors for Antitumor Drug Delivery and Solid Tumor Theranostics by Akasov, R. A., Demina, P. A., Zasedateleva, V. V., Sholina, N. V., Khochenkov, D. A., Generalova, A. N., Selvan, J. Senthil, Khaydukov, E. V., Panchenko, V. Ya

“…—Theranostics is the direction in modern biomedicine aimed at developing drugs that combine the capabilities of diagnosis and therapy of tumors in one agent…”
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EXPRESSION OF THE VASCULAR ENDOTHELIAL GROWTH FACTOR AND ITS RECEPTORS (VEGFR-1 AND VEGFR-2) IN PRIMARY TUMOR CELLS IN PATIENTS WITH RENAL CANCER by Khochenkov, D. A., Volkova, M. I., Timofeev, I. V., Olshanskaya, A. S., Khochenkova, Yu. A., Solomko, E. Sh, Ashuba, S. A., Matveev, V. B.

“…Purpose: to study the expression of vascular endothelial growth factor (vegf-a) and its receptors (vegfr-1 and vegfr-2) in renal cell carcinoma (rcc) cells and…”
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In vitro и in vivo photodynamic therapy of solid tumors with a combination of riboflavin and upconversion nanoparticles by Sholina, N. V., Akasov, R. A., Khochenkov, D. A., Generalova, A. N., Semchishen, V. A., Khaydukov, E. V.

“…Rationale : Riboflavin (vitamin B 2 ) is one of the most promising agents for photodynamic therapy (PDT). However, its use is limited by the excitation in the…”
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Inactivation of Receptor Tyrosine Kinases Overcomes Resistance to Targeted B-RAF Inhibitors in Melanoma Cell Lines by Ryabaya, O O, Malysheva, A A, Khochenkova, Yu A, Solomko, E Sh, Khochenkov, D A

“…The discovery of B-RAF activating mutations in malignant melanoma cells has led to the development of a number of targeted drugs, which block exclusively the…”
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Inactivation of Receptor Tyrosine Kinases Overcomes Resistance to Targeted B-RAF Inhibitors in Melanoma Cell Lines by Ryabaya, O. O., Malysheva, A. A., Khochenkova, Yu. A., Solomko, E. Sh, Khochenkov, D. A.

“…The discovery of B-RAF activating mutations in malignant melanoma cells has led to the development of a number of targeted drugs, which block exclusively the…”
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New approaches in 3D modeling of in vitro growth of primary cultures of malignant gliomas by Khochenkova, Yu. A., Dyrda, I. G., Machkova, Yu. S., Solomko, E. Sh, Sidorova, T. A., Khochenkov, D. A., Avilova, E. A.

“…Background. The incidence of brain gliomas firmly occupies a leading position among all central nervous system tumors – 40–50 % of the cases detected, more…”
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THE ROLE OF EPITHELIAL-TO-MESENCHYMAL TRANSITION AND AUTOPHAGY IN ANTITUMORAL RESPONSE OF MELANOMA CELL LINES TO TARGET INHIBITION OF MEK AND mTOR KINASES by Ryabaya, O. O., Prokofieva, A. A., Khochenkov, D. A., Akasov, R. A., Burov, S. V., Markvicheva, E. A., Stepanova, E. V.

“…Introduction. Cutaneous melanoma is a challenge to treat due to rapid progression of disease and acquired resistance to therapy. Autophagy and the…”
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Antiangiogenic Activity of Alofanib, an Allosteric Inhibitor of Fibroblast Growth Factor Receptor 2 by Khochenkov, D. A., Solomko, E. Sch, Peretolchina, N. M., Ryabaya, O. O., Stepanova, E. V.

“…Alofanib is a potential allosteric inhibitor of FGFR2 used in oncology. The inhibitor blocks the extracellular part of the receptor and prevents its binding…”
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INTERACTION BETWEEN DENDRITIC CELLS AND B CELLS DURING IMMUNE RESPONSE TO T CELL-INDEPENDENT ANTIGENS by Khochenkov, D. A., Gavrilova, M. V.

“…Involvement of dendritic cells (DC) into switching of immune response to T-independent type 2 antigens (TI2 antigens) is poorly studied. The present study…”
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The role of autophagy inhibition in the enhanced cytotoxicity of temozolomide on melanoma cell lines by Ryabaya, O. O., Inshakov, A. N., Malysheva, A. A., Abramov, I. S., Sholina, N. V., Khochenkov, D. A., Stepanova, E. V.

“…Background. Despite advantages in treatment of metastatic melanoma it remains resistant to current therapy. Recent evidence indicates that tumor cells could…”
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