Search Results - "Khoa D. Nguyen"

Enantioselective Formation of All-Carbon Quaternary Centers via C–H Functionalization of Methanol: Iridium-Catalyzed Diene Hydrohydroxymethylation by Nguyen, Khoa D, Herkommer, Daniel, Krische, Michael J

“…The first catalytic enantioselective C–C couplings of methanol (>30 × 106 tons/year) are reported. Insertion of 2-substituted dienes into the methanol C–H bond…”
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Metal-catalyzed reductive coupling of olefin-derived nucleophiles: Reinventing carbonyl addition by Nguyen, Khoa D., Park, Boyoung Y., Luong, Tom, Sato, Hiroki, Garza, Victoria J., Krische, Michael J.

“…α-Olefins are the most abundant petrochemical feedstock beyond alkanes, yet their use in commodity chemical manufacture is largely focused on polymerization…”
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Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture by Paşca, Anca M, Sloan, Steven A, Clarke, Laura E, Tian, Yuan, Makinson, Christopher D, Huber, Nina, Kim, Chul Hoon, Park, Jin-Young, O'Rourke, Nancy A, Nguyen, Khoa D, Smith, Stephen J, Huguenard, John R, Geschwind, Daniel H, Barres, Ben A, Paşca, Sergiu P

“…A method for 3D differentiation of human pluripotent stem cells yields brain cortical spheroids with functional neurons and astrocytes. The spheroids can be…”
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Enantioselective Formation of CF3‑Bearing All-Carbon Quaternary Stereocenters via C–H Functionalization of Methanol: Iridium Catalyzed Allene Hydrohydroxymethylation by Holmes, Michael, Nguyen, Khoa D, Schwartz, Leyah A, Luong, Tom, Krische, Michael J

“…Using an iridium catalyst modified by PhanePhos, CF3-allenes react with methanol to form branched products of hydrohydroxymethylation as single regioisomers…”
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Ruthenium-BINAP Catalyzed Alcohol C–H tert-Prenylation via 1,3-Enyne Transfer Hydrogenation: Beyond Stoichiometric Carbanions in Enantioselective Carbonyl Propargylation by Nguyen, Khoa D, Herkommer, Daniel, Krische, Michael J

“…The chiral ruthenium complex formed in situ from (TFA)2Ru­(CO)­(PPh3)2 and (R)-BINAP is found to catalyze the enantioselective C–C coupling of diverse primary…”
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Thermoneutral Housing Accelerates Metabolic Inflammation to Potentiate Atherosclerosis but Not Insulin Resistance by Tian, Xiao Yu, Ganeshan, Kirthana, Hong, Cynthia, Nguyen, Khoa D., Qiu, Yifu, Kim, Jason, Tangirala, Rajendra K., Tontonoz, Peter, Chawla, Ajay

“…Chronic, low-grade inflammation triggered by excess intake of dietary lipids has been proposed to contribute to the pathogenesis of metabolic disorders, such…”
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Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis by Nguyen, Khoa D., Qiu, Yifu, Cui, Xiaojin, Goh, Y. P. Sharon, Mwangi, Julia, David, Tovo, Mukundan, Lata, Brombacher, Frank, Locksley, Richard M., Chawla, Ajay

“…Exposure to cold drives IL-4-mediated alternative macrophage activation and catecholamine secretion in brown and white adipose tissues to stimulate…”
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Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin by Mauer, Jan, Chaurasia, Bhagirath, Goldau, Julia, Vogt, Merly C, Ruud, Johan, Nguyen, Khoa D, Theurich, Sebastian, Hausen, A Christine, Schmitz, Joel, Brönneke, Hella S, Estevez, Emma, Allen, Tamara L, Mesaros, Andrea, Partridge, Linda, Febbraio, Mark A, Chawla, Ajay, Wunderlich, F Thomas, Brüning, Jens C

“…The role of IL-6 in obesity-associated inflammation remains controversial. Bruening and colleagues identify signaling by IL-6 as an important determinant for…”
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Enantioselective Ruthenium-Catalyzed Carbonyl Allylation via Alkyne–Alcohol C–C Bond-Forming Transfer Hydrogenation: Allene Hydrometalation vs Oxidative Coupling by Liang, Tao, Nguyen, Khoa D, Zhang, Wandi, Krische, Michael J

“…Chiral ruthenium­(II) complexes modified by Josiphos ligands catalyze the reaction of alkynes with primary alcohols to form homoallylic alcohols with excellent…”
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Well-Being Correlates of Perceived Positivity Resonance: Evidence From Trait and Episode-Level Assessments by Major, Brett C., Le Nguyen, Khoa D., Lundberg, Kristjen B., Fredrickson, Barbara L.

“…Positivity resonance is a type of interpersonal connection characterized by shared positivity, mutual care and concern, and behavioral and biological…”
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Loving-kindness meditation slows biological aging in novices: Evidence from a 12-week randomized controlled trial by Le Nguyen, Khoa D., Lin, Jue, Algoe, Sara B., Brantley, Mary M., Kim, Sumi L., Brantley, Jeffrey, Salzberg, Sharon, Fredrickson, Barbara L.

“…•Over 12 weeks, loving-kindness meditation buffered telomere attrition.•Telomere length decreased in the mindfulness group and the control group.•The…”
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Eosinophils secrete IL-4 to facilitate liver regeneration by Goh, Y. P. Sharon, Henderson, Neil C., Heredia, Jose E., Eagle, Alex Red, Odegaard, Justin I., Lehwald, Nadja, Nguyen, Khoa D., Sheppard, Dean, Mukundan, Lata, Locksley, Richard M., Chawla, Ajay

“…The liver is a central organ for the synthesis and storage of nutrients, production of serum proteins and hormones, and breakdown of toxins and metabolites…”
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Shaping of infant B cell receptor repertoires by environmental factors and infectious disease by Nielsen, Sandra C A, Roskin, Krishna M, Jackson, Katherine J L, Joshi, Shilpa A, Nejad, Parastu, Lee, Ji-Yeun, Wagar, Lisa E, Pham, Tho D, Hoh, Ramona A, Nguyen, Khoa D, Tsunemoto, Hannah Y, Patel, Sonal B, Tibshirani, Robert, Ley, Catherine, Davis, Mark M, Parsonnet, Julie, Boyd, Scott D

“…Antigenic exposures at epithelial sites in infancy and early childhood are thought to influence the maturation of humoral immunity and modulate the risk of…”
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Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements by Boyd, Scott D, Gaëta, Bruno A, Jackson, Katherine J, Fire, Andrew Z, Marshall, Eleanor L, Merker, Jason D, Maniar, Jay M, Zhang, Lyndon N, Sahaf, Bita, Jones, Carol D, Simen, Birgitte B, Hanczaruk, Bozena, Nguyen, Khoa D, Nadeau, Kari C, Egholm, Michael, Miklos, David B, Zehnder, James L, Collins, Andrew M

“…Individual variation in the Ig germline gene repertoire leads to individual differences in the combinatorial diversity of the Ab repertoire, but the study of…”
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Germline-encoded specificities and the predictability of the B cell response by Vieira, Marcos C, Palm, Anna-Karin E, Stamper, Christopher T, Tepora, Micah E, Nguyen, Khoa D, Pham, Tho D, Boyd, Scott D, Wilson, Patrick C, Cobey, Sarah

“…Antibodies result from the competition of B cell lineages evolving under selection for improved antigen recognition, a process known as affinity maturation…”
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Bacterial Cellulose‐Based Material from Coconut Water as Efficient Green Adsorbent for Heavy Metal Cations by Nguyen, Hanh M. H., Pham, Co D., Nguyen, Khoa D., Tran, An T. T., Le, Nhan T. H., Ho, Phuoc H., Le, Ha V.

“…Nata de coco produced via coconut water fermentation using Acetobacter xylinum was directly applied to remove metal cations in aqueous solutions without any…”
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An open metal site metal–organic framework Cu(BDC) as a promising heterogeneous catalyst for the modified Friedländer reaction by Phan, Nam T.S., Nguyen, Tung T., Nguyen, Khoa D., Vo, Anh X.T.

“…•Cu(BDC) was used as catalyst for the modified Friedländer.•High conversions were achieved using catalytic amounts of the Cu(BDC).•The catalyst could be…”
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A comprehensive scheme for the objective upper body assessments of subjects with cerebellar ataxia by Tran, Ha, Nguyen, Khoa D, Pathirana, Pubudu N, Horne, Malcolm K, Power, Laura, Szmulewicz, David J

“…Cerebellar ataxia refers to the disturbance in movement resulting from cerebellar dysfunction. It manifests as inaccurate movements with delayed onset and…”
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Preparation of Cu-modified bacterial cellulose aerogels derived from nata de coco towards the enhanced adsorption of hydrophobic organic solvents by Nguyen, Hanh H. M., Tan, Khang V. M., Van, Thanh T. T., Nguyen, Hanh N., Phan, Anh N. Q., Tran, An T. T., Le, Phung K., Le, Kien A., Nguyen, Khoa D., Le, Ha V.

“…This study presented a simple and eco-friendly method to load copper nanoparticles on the surface of bacterial cellulose from nata de coco produced via the…”
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Microglia and Other Cellular Mediators of Immunological Dysfunction in Schizophrenia: A Narrative Synthesis of Clinical Findings by Nguyen, Khoa D, Amerio, Andrea, Aguglia, Andrea, Magnani, Luca, Parise, Alberto, Conio, Benedetta, Serafini, Gianluca, Amore, Mario, Costanza, Alessandra

“…Schizophrenia is a complex psychiatric condition that may involve immune system dysregulation. Since most putative disease mechanisms in schizophrenia have…”
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