Search Results - "Khera, Manoj Kumar"

Synthesis and in vitro activity of novel 1,2,4-triazolo[4,3-a]pyrimidine oxazolidinone antibacterial agents. Part II by Khera, Manoj Kumar, Cliffe, Ian A., Prakash, Om

“…The synthesis and antibacterial activity of 1,2,4-triazolo[4,3-a]pyrimidine oxazolidinones is reported. The synthesis and antibacterial activity of…”
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Synthesis of Conformationally Constrained Analogues of Linezolid:  Structure−Activity Relationship (SAR) Studies on Selected Novel Tricyclic Oxazolidinones by Selvakumar, Natesan, Srinivas, Deekonda, Khera, Manoj Kumar, Kumar, Magadi Sitaram, Mamidi, Rao N. V. S, Sarnaik, Hemanth, Charavaryamath, Chandrashekar, Rao, Bonthu Srinivasa, Raheem, Mohammed A, Das, Jagattaran, Iqbal, Javed, Rajagopalan, Ramanujam

“…In an effort to discover potent antibacterials based on the entropically favored “bioactive conformation” approach, we have designed and synthesized a series…”
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Synthesis of novel tricyclic oxazolidinones by a tandem SN2 and SNAr reaction : SAR studies on conformationally constrained analogues of Linezolid by SELVAKUMAR, N, YADI REDDY, B, SUNIL KUMAR, G, MANOJ KUMAR KHERA, SRINIVAS, D, SITARAM KUMAR, M, DAS, Jagattaran, IQBAL, Javed, TREHAN, Sanjay

“…A series of conformationally constrained analogues of Linezolid were synthesised by employing a tandem SN(2) and SNAr reaction as the key step and tested for…”
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An efficient total synthesis of 9-methoxycarbazole-3-carbaldehyde based on a novel methodology for the preparation of methoxyindoles by Selvakumar, N., Khera, Manoj Kumar, Reddy, B.Yadi, Srinivas, D., Azhagan, A.Malar, Iqbal, Javed

“…A direct synthesis of naturally occurring 9-methoxycarbazole-3-carbaldehyde 1 , based on our methodology for the synthesis of 1-methoxyindoles, is reported. A…”
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In Vitro and In Vivo Activities of DS-2969b, a Novel GyrB Inhibitor, against Clostridium difficile by Mathur, Tarun, Barman, Tarani Kanta, Kumar, Manoj, Singh, Diksha, Kumar, Ram, Khera, Manoj Kumar, Yamada, Makiko, Inoue, Shin-Ichi, Upadhyay, Dilip Jatashankar, Masuda, Nobuhisa

“…DS-2969b is a novel GyrB inhibitor that is currently under clinical development for the treatment of infection (CDI). In this study, the and activities of…”
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Synthesis of novel tricyclic oxazolidinones by a tandem SN 2 and SNAr reaction: SAR studies on conformationally constrained analogues of Linezolid by Selvakumar, N., Yadi Reddy, B., Sunil Kumar, G., Khera, Manoj Kumar, Srinivas, D., Sitaram Kumar, M., Das, Jagattaran, Iqbal, Javed, Trehan, Sanjay

“…The synthesis of a series of tricyclic oxazolidinones employing a tandem SN 2 and SNAr reaction as the key step is disclosed. SAR studies on these novel…”
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A direct entry to the 1-methoxyindole skeleton and to the corresponding indoles by a novel rearrangement: general syntheses of substituted 1-methoxyindoles by Selvakumar, N, Reddy, B.Yadi, Azhagan, A.Malar, Khera, Manoj Kumar, Babu, J.Moses, Iqbal, Javed

“…A short and efficient route to 1-methoxyindoles via a novel rearrangement is disclosed. This route involves only three steps from commercially available nitro…”
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Influence of ethylene-Oxy spacer group on the activity of linezolid: Synthesis of potent antibacterials possessing a thiocarbonyl group by Selvakumar, N., Raheem, Mohammed A., Khera, Manoj Kumar, Rajale, Trideep V., Kumar, Magadi Sitaram, Kandepu, Sreenivas, Das, Jagattaran, Rajagopalan, R., Iqbal, Javed, Trehan, Sanjay

“…The influence of an ethylene-oxy spacer element between the heterocycle and the aromatic ring in linezolid is reported. The introduction of such spacer group…”
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Influence of ethylene-oxy spacer group on the activity of linezolid: Synthesis of potent antibacterials possessing a thiocarbonyl groups: Antibacterial agents: solutions for the evolving problems of resistance by SELVAKUMAR, N, RAHEEM, Mohammed A, MANOJ KUMAR KHERA, RAJALE, Trideep V, MAGADI SITARAM KUMAR, KANDEPU, Sreenivas, DAS, Jagattaran, RAJAGOPALAN, R, IQBAL, Javed, TREHAN, Sanjay

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