Search Results - "Kheir, Tony Bou"

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells by Sancho, Patricia, Burgos-Ramos, Emma, Tavera, Alejandra, Bou Kheir, Tony, Jagust, Petra, Schoenhals, Matthieu, Barneda, David, Sellers, Katherine, Campos-Olivas, Ramon, Graña, Osvaldo, Viera, Catarina R., Yuneva, Mariia, Sainz, Bruno, Heeschen, Christopher

“…The anti-diabetic drug metformin targets pancreatic cancer stem cells (CSCs), but not their differentiated progenies (non-CSCs), which may be related to…”
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miR-449 inhibits cell proliferation and is down-regulated in gastric cancer by Bou Kheir, Tony, Futoma-Kazmierczak, Ewa, Jacobsen, Anders, Krogh, Anders, Bardram, Linda, Hother, Christoffer, Grønbæk, Kirsten, Federspiel, Birgitte, Lund, Anders H, Friis-Hansen, Lennart

“…Gastric cancer is the fourth most common cancer in the world and the second most prevalent cause of cancer related death. The development of gastric cancer is…”
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The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1 by Cioffi, Michele, Trabulo, Sara M, Vallespinos, Mireia, Raj, Deepak, Kheir, Tony Bou, Lin, Meng-Lay, Begum, Julfa, Baker, Ann-Marie, Amgheib, Ala, Saif, Jaimy, Perez, Manuel, Soriano, Joaquim, Desco, Manuel, Gomez-Gaviro, Maria Victoria, Cusso, Lorena, Megias, Diego, Aicher, Alexandra, Heeschen, Christopher

“…The stromal microenvironment controls response to injury and inflammation, and is also an important determinant of cancer cell behavior. However, our…”
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DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster by Zagorac, Sladjana, Alcala, Sonia, Fernandez Bayon, Gustavo, Bou Kheir, Tony, Schoenhals, Matthieu, González-Neira, Anna, Fernandez Fraga, Mario, Aicher, Alexandra, Heeschen, Christopher, Sainz, Jr, Bruno

“…Pancreatic ductal adenocarcinoma (PDAC) and other carcinomas are hierarchically organized, with cancer stem cells (CSC) residing at the top of the hierarchy,…”
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Inhibiting NR5A2 targets stemness in pancreatic cancer by disrupting SOX2/MYC signaling and restoring chemosensitivity by Zheng, Quan, Tang, Jiajia, Aicher, Alexandra, Bou Kheir, Tony, Sabanovic, Berina, Ananthanarayanan, Preeta, Reina, Chiara, Chen, Minchun, Gu, Jian-Min, He, Bin, Alcala, Sonia, Behrens, Diana, Lawlo, Rita T, Scarpa, Aldo, Hidalgo, Manuel, Sainz, Jr, Bruno, Sancho, Patricia, Heeschen, Christopher

“…Pancreatic ductal adenocarcinoma (PDAC) is a profoundly aggressive and fatal cancer. One of the key factors defining its aggressiveness and resilience against…”
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Epigenetic dynamics across the cell cycle by Bou Kheir, Tony, Lund, Anders H

“…Progression of the mammalian cell cycle depends on correct timing and co-ordination of a series of events, which are managed by the cellular transcriptional…”
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Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation by Tomaz, Rute A, Harman, Jennifer L, Karimlou, Donja, Weavers, Lauren, Fritsch, Lauriane, Bou-Kheir, Tony, Bell, Emma, Del Valle Torres, Ignacio, Niakan, Kathy K, Fisher, Cynthia, Joshi, Onkar, Stunnenberg, Hendrik G, Curry, Edward, Ait-Si-Ali, Slimane, Jørgensen, Helle F, Azuara, Véronique

“…Jmjd2 H3K9 demethylases cooperate in promoting mouse embryonic stem cell (ESC) identity. However, little is known about their importance at the exit of ESC…”
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Loss of PRDM11 promotes MYC-driven lymphomagenesis by Fog, Cathrine Kolster, Asmar, Fazila, Côme, Christophe, Jensen, Klaus Thorleif, Johansen, Jens Vilstrup, Kheir, Tony Bou, Jacobsen, Linda, Friis, Carsten, Louw, Alison, Rosgaard, Louise, Øbro, Nina Friesgaard, Marquart, Hanne Vibeke, Anthonsen, Kristian, Braat, Arie Koen, van Lohuizen, Maarten, Ralfkiaer, Elisabeth, Grønbæk, Kirsten, Lund, Anders Henrik

“…The PR-domain (PRDM) family of genes encodes transcriptional regulators, several of which are deregulated in cancer. By using a functional screening approach,…”
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