Search Results - "Khedri, Zahra"

AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies by Yamada, Kei, Shikida, Natsuki, Shimbo, Kazutaka, Ito, Yuji, Khedri, Zahra, Matsuda, Yutaka, Mendelsohn, Brian A.

“…The need for atom‐precise biomolecule modification, and particularly the irreversible formation of covalent bonds to specific amino acids in proteins, has…”
Get full text

Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1 by Chen, Guo-Yun, Brown, Nicholas K, Wu, Wei, Khedri, Zahra, Yu, Hai, Chen, Xi, van de Vlekkert, Diantha, D'Azzo, Alessandra, Zheng, Pan, Liu, Yang

“…Both pathogen- and tissue damage-associated molecular patterns induce inflammation through toll-like receptors (TLRs), while sialic acid-binding immunoglobulin…”
Get full text

An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism by Song, Hao, Qi, Jianxun, Khedri, Zahra, Diaz, Sandra, Yu, Hai, Chen, Xi, Varki, Ajit, Shi, Yi, Gao, George F

“…Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D…”
Get full text

Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus by Owen, C. David, Tailford, Louise E., Monaco, Serena, Šuligoj, Tanja, Vaux, Laura, Lallement, Romane, Khedri, Zahra, Yu, Hai, Lecointe, Karine, Walshaw, John, Tribolo, Sandra, Horrex, Marc, Bell, Andrew, Chen, Xi, Taylor, Gary L., Varki, Ajit, Angulo, Jesus, Juge, Nathalie

“…Ruminococcus gnavus is a human gut symbiont wherein the ability to degrade mucins is mediated by an intramolecular trans -sialidase ( Rg NanH). Rg NanH…”
Get full text

Generation means analysis of traits related to lodging using two crosses of durum × emmer wheat by Mohammadi, Majid, Mirlohi, Aghafakhr, Majidi, Mohammad Mahdi, Khedri, Zahra, Rezaei, Vahid

“…Lodging is one of the most important factors that affect wheat final yield. Emmer [Triticum turgidum subsp. dicoccum (Schrank ex Schübl.) Thell.] is a likely…”
Get full text

Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk by Samraj, Annie N, Bertrand, Kimberly A, Luben, Robert, Khedri, Zahra, Yu, Hai, Nguyen, Dzung, Gregg, Christopher J, Diaz, Sandra L, Sawyer, Sherilyn, Chen, Xi, Eliassen, Heather, Padler-Karavani, Vered, Wu, Kana, Khaw, Kay-Tee, Willett, Walter, Varki, Ajit

“…N-glycolylneuraminic acid (Neu5Gc) is a non-human red-meat-derived sialic acid immunogenic to humans. Neu5Gc can be metabolically incorporated into glycan…”
Get full text

Novel aspects of sialoglycan recognition by the Siglec-like domains of streptococcal SRR glycoproteins by Bensing, Barbara A, Khedri, Zahra, Deng, Lingquan, Yu, Hai, Prakobphol, Akraporn, Fisher, Susan J, Chen, Xi, Iverson, Tina M, Varki, Ajit, Sullam, Paul M

“…Serine-rich repeat glycoproteins are adhesins expressed by commensal and pathogenic Gram-positive bacteria. A subset of these adhesins, expressed by oral…”
Get full text

Distribution of O-Acetylated Sialic Acids among Target Host Tissues for Influenza Virus by Wasik, Brian R, Barnard, Karen N, Ossiboff, Robert J, Khedri, Zahra, Feng, Kurtis H, Yu, Hai, Chen, Xi, Perez, Daniel R, Varki, Ajit, Parrish, Colin R

“…Sialic acids (Sias) are important glycans displayed on the cells and tissues of many different animals and are frequent targets for binding and modification by…”
Get full text

Chemoenzymatic Synthesis of GD3 Oligosaccharides and Other Disialyl Glycans Containing Natural and Non-natural Sialic Acids by Yu, Hai, Cheng, Jiansong, Ding, Li, Khedri, Zahra, Chen, Yi, Chin, Sharlene, Lau, Kam, Tiwari, Vinod Kumar, Chen, Xi

“…In order to understand the biological importance of naturally occurring sialic acid variations on disialyl structures in nature, we developed an efficient…”
Get full text

Studies on the Detection, Expression, Glycosylation, Dimerization, and Ligand Binding Properties of Mouse Siglec-E by Siddiqui, Shoib, Schwarz, Flavio, Springer, Stevan, Khedri, Zahra, Yu, Hai, Deng, Lingquan, Verhagen, Andrea, Naito-Matsui, Yuko, Jiang, Weiping, Kim, Daniel, Zhou, Jie, Ding, Beibei, Chen, Xi, Varki, Nissi, Varki, Ajit

“…CD33-related Siglecs are a family of proteins widely expressed on innate immune cells. Binding of sialylated glycans or other ligands triggers signals that…”
Get full text

Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates by Hayakawa, Toshiyuki, Khedri, Zahra, Schwarz, Flavio, Landig, Corinna, Liang, Suh-Yuen, Yu, Hai, Chen, Xi, Fujito, Naoko T, Satta, Yoko, Varki, Ajit, Angata, Takashi

“…Siglecs-11 and -16 are members of the sialic acid recognizing Ig-like lectin family, and expressed in same cells. Siglec-11 functions as an inhibitory…”
Get full text

Decreasing the sialidase activity of multifunctional Pasteurella multocida α2-3-sialyltransferase 1 (PmST1) by site-directed mutagenesis by Sugiarto, Go, Lau, Kam, Li, Yanhong, Khedri, Zahra, Yu, Hai, Le, Diem-Thuy, Chen, Xi

“…Pasteurella multocida α2-3-sialyltransferase 1 (PmST1) is a multifunctional enzyme which has α2-6-sialyltransferase, α2-3-sialidase, and α2-3-trans-sialidase…”
Get more information

Correction: An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism by Song, Hao, Qi, Jianxun, Khedri, Zahra, Diaz, Sandra, Yu, Hai, Chen, Xi, Varki, Ajit, Shi, Yi, Gao, George F

Get full text

AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies by Yamada, Kei, Shikida, Natsuki, Shimbo, Kazutaka, Ito, Yuji, Khedri, Zahra, Matsuda, Yutaka, Mendelsohn, Brian A.

“…The need for atom‐precise biomolecule modification, and particularly the irreversible formation of covalent bonds to specific amino acids in proteins, has…”
Get full text

Encoding and Estimating the Remarkable Diversity of Possible Sialyltrisaccharides in Nature by Sasmal, Aniruddha, Khedri, Zahra, Diaz, Sandra, Lewis, Nathan, Varki, Ajit

“…Glycan microarray development is a critical need for high throughput analysis of glycan‐protein interactions. Over last few years we have collaborated with…”
Get full text

Sialoglycan-binding patterns of bacterial AB5 toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits by Khan, Naazneen, Sasmal, Aniruddha, Khedri, Zahra, Secrest, Patrick, Verhagen, Andrea, Srivastava, Saurabh, Varki, Nissi, Chen, Xi, Yu, Hai, Beddoe, Travis, Paton, Adrienne W., Paton, James C., Varki, Ajit

“…Many pathogenic bacteria secrete AB5 toxins that can be virulence factors. Cytotoxic A subunits are delivered to the cytosol following B subunit binding to…”
Get full text

Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome by Srivastava, Saurabh, Verhagen, Andrea, Sasmal, Aniruddha, Wasik, Brian R, Diaz, Sandra, Yu, Hai, Bensing, Barbara A, Khan, Naazneen, Khedri, Zahra, Secrest, Patrick, Sullam, Paul, Varki, Nissi, Chen, Xi, Parrish, Colin R, Varki, Ajit

“…Glycans that are abundantly displayed on vertebrate cell surface and secreted molecules are often capped with terminal sialic acids (Sias). These diverse…”
Get full text

Triazole-linked transition state analogs as selective inhibitors against V. cholerae sialidase by Slack, Teri J., Li, Wanqing, Shi, Dashuang, McArthur, John B., Zhao, Gengxiang, Li, Yanhong, Xiao, An, Khedri, Zahra, Yu, Hai, Liu, Yang, Chen, Xi

“…[Display omitted] Sialidases or neuraminidases are enzymes that catalyze the cleavage of terminal sialic acids from oligosaccharides and glycoconjugates. They…”
Get full text

Rapid Evolution of Bacterial Exotoxin B Subunits Independent of A subunits: Sialic Acid Binding Preferences Correlate with Host Range and Intrinsic Toxicity by KHAN, NAAZNEEN, Verhagen, Andrea, Khedri, Zahra, Diaz, Sandra, Varki, Nissi, Paton, Adrienne, Beddoe, Travis, Paton, James, Varki, Ajit

“…Several well‐known AB bacterial toxins have cytotoxic A subunits that are delivered to the cytosol following B subunit binding to terminal sialic…”
Get full text

Development of Sialoglycan Recognizing Probes (SGRPs) With Defined Specificities: Towards Exploring the Dynamic Mammalian Sialoglycome by Srivastava, Saurabh, Verhagen, Andrea, Wasik, Brian, Yu, Hai, Sasmal, Aniruddha, Bensing, Barbara, Khan, Naazneen, Khedri, Zahra, Diaz, Sandra, Sullam, Paul, Varki, Nissi, Chen, Xi, Parrish, Colin, Varki, Ajit

“…Dense and complex glycans on vertebrate cell surfaces and secreted molecules often terminate with sialic acids (Sias), a diverse family of sugars involved in…”
Get full text