Search Results - "Khayyat, Ahdab N"

Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives by Khayyat, Ahdab N, Mohamed, Khaled O, Malebari, Azizah M, El-Malah, Afaf

“…A new series of benzotriazole moiety bearing substituted imidazol-2-thiones at N1 has been designed, synthesized and evaluated for in vitro anticancer activity…”
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Development of Advanced 3D-Printed Solid Dosage Pediatric Formulations for HIV Treatment by Malebari, Azizah M, Kara, Aytug, Khayyat, Ahdab N, Mohammad, Khadijah A, Serrano, Dolores R

“…The combination of lopinavir/ritonavir remains one of the first-line therapies for the initial antiretroviral regimen in pediatric HIV-infected children…”
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Selective COX-2 Inhibitors: Road from Success to Controversy and the Quest for Repurposing by El-Malah, Afaf A, Gineinah, Magdy M, Deb, Pran Kishore, Khayyat, Ahdab N, Bansal, Monika, Venugopala, Katharigatta N, Aljahdali, Anfal S

“…The introduction of selective COX-2 inhibitors (so-called 'coxibs') has demonstrated tremendous commercial success due to their claimed lower potential of…”
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Accumulation of oxysterols in the erythrocytes of COVID-19 patients as a biomarker for case severity by Khedr, Alaa, Khayat, Maan T, Khayyat, Ahdab N, Asfour, Hany Z, Alsilmi, Rahmah A, Kammoun, Ahmed K

“…Abstract Background Due to the high risk of COVID-19 patients developing thrombosis in the circulating blood, atherosclerosis, and myocardial infarction, it is…”
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Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles by Khayat, Maan T., Zarka, Mohamed A., El-Telbany, Dalia Farag. A., El-Halawany, Ali M., Kutbi, Hussam Ibrahim, Elkhatib, Walid F., Noreddin, Ayman M., Khayyat, Ahdab N., El-Telbany, Rania Farag A., Hammad, Sherif F., Abdel-Naim, Ashraf B., Alolayan, Ebtesam M., Al-Sawahli, Majid Mohammad

“…Resveratrol (RSV), a non-flavonoid stilbene polyphenol, possesses anti-carcinogenic activities against all the major stages of cancer. Zein nanoparticles (ZN…”
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Synergistic Benefits: Exploring the Anti-Virulence Effects of Metformin/Vildagliptin Antidiabetic Combination against Pseudomonas aeruginosa via Controlling Quorum Sensing Systems by Khayat, Maan T, Abbas, Hisham A, Ibrahim, Tarek S, Elbaramawi, Samar S, Khayyat, Ahdab N, Alharbi, Majed, Hegazy, Wael A H, Yehia, Fatma Al-Zahraa A

“…The repurposing of drugs is one of the most competent strategies for discovering new antimicrobial agents. Vildagliptin is a dipeptidyl peptidase-4 inhibitor…”
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HPLC Determination of Imidazoles with Variant Anti-Infective Activity in Their Dosage Forms and Human Plasma by Ali, Oday T, Hassan, Wafaa S, Khayyat, Ahdab N, Almalki, Ahmad J, Sebaiy, Mahmoud M

“…A suitable HPLC method has been selected and validated for rapid simultaneous separation and determination of four imidazole anti-infective drugs, secnidazole,…”
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Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer by Khayyat, Ahdab N., Abbas, Hisham A., Mohamed, Mamdouh F. A., Asfour, Hani Z., Khayat, Maan T., Ibrahim, Tarek S., Youns, Mahmoud, Khafagy, El-Sayed, Abu Lila, Amr S., Safo, Martin K., Hegazy, Wael A. H.

“…Diabetic foot ulcers are recognized to be a severe complication of diabetes, increasing the risk of amputation and death. The bacterial infection of Diabetic…”
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Xylitol Inhibits Growth and Blocks Virulence in Serratia marcescens by Khayyat, Ahdab N., Hegazy, Wael A. H., Shaldam, Moataz A., Mosbah, Rasha, Almalki, Ahmad J., Ibrahim, Tarek S., Khayat, Maan T., Khafagy, El-Sayed, Soliman, Wafaa E., Abbas, Hisham A.

“…Serratia marcescens is an opportunistic nosocomial pathogen and causes wound and burn infections. It shows high resistance to antibiotics and its pathogenicity…”
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The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme by Malebari, Azizah M., Ibrahim, Tarek S., Salem, Ibrahim M., Salama, Ismail, Khayyat, Ahdab N., Mostafa, Samia M., El-Sabbagh, Osama I., Darwish, Khaled M.

“…The membrane-bound human carbonic anhydrase (hCA) IX is widely recognized as a marker of tumor hypoxia and a prognostic factor within several human cancers…”
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Secnidazole Is a Promising Imidazole Mitigator of Serratia marcescens Virulence by Khayyat, Ahdab N., Abbas, Hisham A., Khayat, Maan T., Shaldam, Moataz A., Askoura, Momen, Asfour, Hani Z., Khafagy, El-Sayed, Abu Lila, Amr S., Allam, Ahmed N., Hegazy, Wael A. H.

“…Serratia marcescens is an opportunistic pathogen that causes diverse nosocomial infections. S. marcescens has developed considerable resistance to different…”
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A green approach to the analysis of co-administered ampicillin/sulbactam and paracetamol in human urine by SELIM, BASMA M., ABDELSALAM, RANDA A., EL-GINDY, ALAA, EID, BASMA G., NEAMATALLAH, THIKRYAT, KHAYYAT, AHDAB N., HADAD, GHADA M., ELKHOUDARY, MAHMOUD M.

“…The novelty of this work is the simultaneous analysis of sulbactam (SUL), ampicillin (AMP), and paracetamol (PARA) in human urine samples, using the…”
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In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors by Ibrahim, Tarek S, Taher, Ehab S, Samir, Ebtihal, M Malebari, Azizah, Khayyat, Ahdab N, Mohamed, Mamdouh F A, Bokhtia, Riham M, AlAwadh, Mohammed A, Seliem, Israa A, Asfour, Hani Z, Alhakamy, Nabil A, Panda, Siva S, Al-Mahmoudy, Amany M M

“…Two sets of diphenyl ether derivatives incorporating five-membered 1,3,4-oxadiazoles, and their open-chain aryl hydrazone analogs were synthesized in good…”
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Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis by Khayat, Maan T, Ibrahim, Tarek S, Darwish, Khaled M, Khayyat, Ahdab N, Alharbi, Majed, Khafagy, El-Sayed, Ali, Mohamed A M, Hegazy, Wael A H, Abbas, Hisham A

“…Bacteria communicate with each other using quorum sensing (QS) which works in an inducer/receptor manner. QS plays the main role in orchestrating diverse…”
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Ultra-performance liquid chromatography-tandem mass spectrometric method for quantitation of the recently Food and Drug Administration approved combination of vaborbactam and meropenem in human plasma by Kammoun, Ahmed K, Khedr, Alaa, Khayyat, Ahdab N, Hegazy, Maha A

“…A parenteral medical combination containing vaborbactam and meropenem is used mainly to treat complicated urinary tract infections. A novel ultra-performance…”
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Anti-Quorum Sensing Activities of Gliptins against Pseudomonas aeruginosa and Staphylococcus aureus by Khayat, Maan T, Abbas, Hisham A, Ibrahim, Tarek S, Khayyat, Ahdab N, Alharbi, Majed, Darwish, Khaled M, Elhady, Sameh S, Khafagy, El-Sayed, Safo, Martin K, Hegazy, Wael A H

“…The development of bacterial resistance to traditional antibiotics constitutes an emerging public health issue. Promising approaches have been innovated to…”
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Sodium Citrate Alleviates Virulence in Pseudomonas aeruginosa by Khayat, Maan T, Ibrahim, Tarek S, Khayyat, Ahdab N, Alharbi, Majed, Shaldam, Moataz A, Mohammad, Khadijah A, Khafagy, El-Sayed, El-Damasy, Dalia A, Hegazy, Wael A H, Abbas, Hisham A

“…The development of bacterial resistance is an insistent global health care issue, especially in light of the dwindled supply of new antimicrobial agents. This…”
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Exploitation of multi-walled carbon nanotubes/Cu()-metal organic framework based glassy carbon electrode for the determination of orphenadrine citrate by Kammoun, Ahmed K, Abdelrahman, Mona H, Khayyat, Ahdab N, Elbaramawi, Samar S, Ibrahim, Tarek S, Abdallah, Nehad A

“…Metal organic frameworks (MOFs), with structural tunability, high metal content and large surface area have recently attracted the attention of researchers in…”
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A sensitive liquid chromatography-tandem mass spectrometric method for determination of five β-blockers after labeling with either hydrazonoyl chloride or dansyl chloride reagent by Khedr, Alaa, Khayyat, Ahdab N., El-Shorbagi, Abdel-Nasser A., Kammoun, Ahmed K.

“…•Derivatization of five β-blockers with hydrazonoyl chloride and dansyl chloride.•Relative MS response of labeled to unlabeled is improved 2.3 to 3.7…”
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A new approach for characterization of phosphatidylcholines and lysophosphatidylcholine in human plasma by Khedr, Alaa, Khayat, Maan T, Khayyat, Ahdab N

“…Aim: Characterization of phosphatidylcholines (PCs) and lysophosphatidylcholine in human plasma using LC-IT-MSn. The characterization approach was based on…”
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