Search Results - "Khaw, P.T"

Toxicity of natural tear substitutes in a fully defined culture model of human corneal epithelial cells by Geerling, G., Daniels, J.T., Dart, J.K.G., Cree, I.A., Khaw, P.T.

“…Serum and saliva have recently been advocated as natural tear substitutes for intractable aqueous-deficient dry eyes, but the effects of these fluids on…”
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Skin and oral fibroblasts exhibit phenotypic differences in extracellular matrix reorganization and matrix metalloproteinase activity by Stephens, P., Davies, K.J., Occleston, N., Pleass, R.D., Kon, C., Daniels, J., Khaw, P.T., Thomas, D.W.

“…Background Oral mucosal wounds are characterized by rapid re‐epithelialization and remodelling. In vitro, oral mucosal fibroblasts exhibit a fetal phenotype…”
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The Role of the Immune System in Conjunctival Wound Healing After Glaucoma Surgery by Chang, L, Crowston, J.G, Cordeiro, M.Francesca, Akbar, A.N, Khaw, P.T

“…The immune system has a fundamental role in the development and regulation of ocular healing, which plays an important role in the pathogenesis of most…”
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The influence of mmp activity on force generation by dupuytren's fibroblasts by Townley, W.A, Klass, B, Rolfe, K.J, Cambrey, A.D, Khaw, P.T, Grobbelaar, A.O

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Prospects for the application of Müller glia and their derivatives in retinal regenerative therapies by Eastlake, K., Lamb, W.D.B., Luis, J., Khaw, P.T., Jayaram, H., Limb, G.A.

“…Neural cell death is the main feature of all retinal degenerative disorders that lead to blindness. Despite therapeutic advances, progression of retinal…”
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Receptor‐targeted liposome‐peptide‐si RNA nanoparticles represent a novel and efficient si RNA delivery system to prevent conjunctival fibrosis by Yu‐Wai‐Man, C., Tagalakis, A., Manunta, M., Hart, S.L., Khaw, P.T.

“…Abstract only…”
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Receptor‐targeted liposome‐peptide‐si RNA nanoparticles represent a novel and efficient si RNA delivery system to prevent conjunctival fibrosis by Yu‐Wai‐Man, C., Tagalakis, A., Manunta, M., Hart, S.L., Khaw, P.T.

“…Abstract only…”
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Strategies for optic nerve rescue and regeneration in glaucoma and other optic neuropathies by Dahlmann-Noor, A.H., Vijay, S., Limb, G. Astrid, Khaw, P.T.

“…Glaucoma is the most common age-related optic nerve disease and also the most common neuropathy, affecting ∼60 million people worldwide in its most common…”
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Downregulating the Myocardin‐related transcription factor/ Serum response factor (MRTF/SRF) pathway is a novel therapeutic approach to prevent post‐surgical fibrosis in glaucoma by Yu‐Wai‐Man, C., Treisman, R., Khaw, P.T., Bailly, M.

“…Purpose Glaucoma is the first leading cause of irreversible blindness worldwide and fibrosis is the main cause of failure of glaucoma surgery. There are…”
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Receptor‐targeted liposome‐peptide‐siRNA nanoparticles represent a novel and efficient siRNA delivery system to prevent conjunctival fibrosis by Yu‐Wai‐Man, C., Tagalakis, A., Manunta, M., Hart, S.L., Khaw, P.T.

“…Purpose Glaucoma is the leading cause of irreversible blindness worldwide and fibrosis is the main cause of failure of glaucoma surgery. We have previously…”
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Receptor‐targeted liposome‐peptide‐siRNA nanoparticles represent a novel and efficient siRNA delivery system to prevent conjunctival fibrosis by Yu‐Wai‐Man, C., Tagalakis, A., Manunta, M., Hart, S.L., Khaw, P.T.

“…Purpose Glaucoma is the leading cause of irreversible blindness worldwide and fibrosis is the main cause of failure of glaucoma surgery. We have previously…”
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Transplanted olfactory ensheathing cells incorporated into the optic nerve head ensheathe retinal ganglion cell axons: Possible relevance to glaucoma by Li, Y., Li, D., Khaw, P.T., Raisman, G.

“…A mixture of olfactory ensheathing cells and fibroblasts cultured from the adult rat olfactory mucosa was transplanted through a scleral incision into the…”
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Triamcinolone attenuates macrophage/microglia accumulation associated with NMDA-induced RGC death and facilitates survival of Müller stem cell grafts by Singhal, S., Lawrence, J.M., Salt, T.E., Khaw, P.T., Limb, G.A.

“…Retinal ganglion cell (RGC) death in glaucoma models is associated with accumulation of activated microglia, a sign of neural degeneration which has been shown…”
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Defining “occludable” angles in population surveys: drainage angle width, peripheral anterior synechiae, and glaucomatous optic neuropathy in east Asian people by Foster, P J, Aung, T, Nolan, W P, Machin, D, Baasanhu, J, Khaw, P T, Alsbirk, P-H, Lee, P S, Seah, S K L, Johnson, G J

“…Background/aim: A current consensus in epidemiological studies of primary angle closure (PAC) is to diagnose the condition only if the posterior (usually…”
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Intraocular pressure and visual field loss in primary angle closure and primary open angle glaucomas by Gazzard, G, Foster, P J, Devereux, J G, Oen, F, Chew, P, Khaw, P T, Seah, S

“…Aim: To compare the correlation between visual field loss and the pretreatment intraocular pressure (IOP) in primary angle closure glaucoma (PACG) and primary…”
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Inhibition of matrix metalloproteinase activity reduces collagen lattice contraction by Dupuytren's fibroblasts by Townley, W., Cambrey, A.D., Khaw, P.T., Grobbelaar, A.O.

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Gene therapy: new "magic bullets" to prevent ocular scarring; will the advances in modern molecular biology open doors to new therapies? by Khaw, P.T, Cambrey, A.D, Limb, G.A, Daniels, J.T

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T lymphocyte mediated lysis of mitomycin C treated Tenon’s capsule fibroblasts by Crowston, J G, Chang, L H, Daniels, J T, Khaw, P T, Akbar, A N

“…Aims: To evaluate the effect of T cell co-culture on mitomycin C treated and untreated Tenon’s capsule fibroblasts. Methods: IL-2 dependent allogeneic T cells…”
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Surgery for glaucoma in the 21st century by Khaw, P T, Wells, A P, Lim, K S

“…The presence of a bleb in patients undergoing viscocanalostomy strongly suggests that subconjunctival drainage is occurring, which is likely given that it is…”
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The effects of single doses of β radiation on the wound healing behaviour of human Tenon’s capsule fibroblasts by Constable, P H, Crowston, J G, Occleston, N L, Khaw, P T

“…Aim: To determine the effects of single doses of β radiation on the wound healing functions of human Tenon’s capsule fibroblasts (hTf). Methods: hTf were grown…”
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