Search Results - "Khavinson, V Kh"

Peptide KED: Molecular-Genetic Aspects of Neurogenesis Regulation in Alzheimer’s Disease by Khavinson, V. Kh, Lin’kova, N. S., Umnov, R. S.

“…Neuroprotective peptides are promising candidate molecules for the treatment of Alzheimer’s disease (AD). Oral application of KED (Lys-Glu-Asp) improved memory…”
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Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells by Khavinson, V. Kh, Linkova, N. S., Kvetnoy, I. M., Polyakova, V. O., Drobintseva, A. O., Kvetnaia, T. V., Ivko, O. M.

“…Thymalin is a polypeptide complex isolated from the thymus and regulating the functions of the immune system. Thymalin is effective in therapy of acute…”
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Comparison of the Effects of KE and AED Peptides on Functional Activity of Human Skin Fibroblasts during Their Replicative Aging by Fridman, N. V., Linkova, N. S., Kozhevnikova, E. O., Gutop, E. O., Khavinson, V. Kh

“…We studied the effect of KE and AED peptides on the expression of sirtuin-1, sirtuin-6, collagen I, cytokines (IL-1, TGF-β), and transcription factor NF-κB in…”
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Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19 by Khavinson, V Kh, Kuznik, B I, Trofimova, S V, Volchkov, V A, Rukavishnikova, S A, Titova, O N, Akhmedov, T A, Trofimov, A V, Potemkin, V V, Magen, E

“…The paper presents the results of a standard and complex treatment method using the peptide drug thymus thymalin in patients with COVID-19. One of the…”
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Peptide KE in Human Proteome by Terekhov, A. Yu, Kormilets, D. Yu, Linkova, N. S., Kuznik, B. I., Mar’yanovich, A. T., Khavinson, V. Kh

“…Peptide KE exhibits immunoprotective, geroprotective, and oncostatic activities and stimulates functional activity of fibroblasts. The KE motif is present in…”
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Identification of Peptide AEDG in the Polypeptide Complex of the Pineal Gland by Khavinson, V. Kh, Kopylov, A. T., Vaskovsky, B. V., Ryzhak, G. A., Lin’kova, N. S.

“…The polypeptide complex of the epiphysis and the peptide AEDG, constructed on the basis of its amino acid analysis, exert similar biological effects. Both…”
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Effect of Peptide AEDG on Telomere Length and Mitotic Index of PHA-Stimulated Human Blood Lymphocytes by Khavinson, V. Kh, Pendina, A. A., Efimova, O. A., Tikhonov, A. V., Koltsova, A. S., Krapivin, M. I., Petrovskaia-Kaminskaia, A. V., Petrova, L. I., Lin’kova, N. S., Baranov, V. S.

“…We studied the effect of peptide AEDG on telomere length and mitotic index of PHA-stimulated blood lymphocytes from young (18-22 years, N=5) and middle-aged…”
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Nephroprotective Effect of EDL Peptide at Acute Injury of Kidneys of Different Genesis by Zamorskii, I. I., Shchudrova, T. S., Lin’kova, N. S., Nichik, T. E., Khavinson, V. Kh

“…EDL peptide produced a nephroprotective effect on experimental models gentamycin-induced nephropathy and ischemia/reperfusion kidney injury in rats. The…”
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The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity by Khavinson, V. Kh, Linkova, N. S., Chalisova, N. I., Ivko, O. M.

“…The polypeptide drug thymalin is used for various diseases associated with immune dysfunction, viral and bacterial infections, regeneration normalization,…”
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Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells by Ashapkin, V. V., Linkova, N. S., Khavinson, V. Kh, Vanyushin, B. F.

“…Expression levels of genes encoding specific transcription factors and other functionally important proteins vary upon aging of pancreatic and bronchial…”
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Short exogenous peptides regulate expression of CLE, KNOX1, and GRF family genes in Nicotiana tabacum by Fedoreyeva, L. I., Dilovarova, T. A., Ashapkin, V. V., Martirosyan, Yu. Ts, Khavinson, V. Kh, Kharchenko, P. N., Vanyushin, B. F.

“…Exogenous short biologically active peptides epitalon (Ala-Glu-Asp-Gly), bronchogen (Ala-Glu-Asp-Leu), and vilon (Lys-Glu) at concentrations 10 –7 -10 –9 M…”
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Epigenetic Mechanisms of Peptide-Driven Regulation and Neuroprotective Protein FKBP1b by Kuznik, B. I., Davydov, S. O., Popravka, E. S., Lin’kova, N. S., Kozina, L. S., Khavinson, V. Kh

“…Cortexin is a clinically approved cerebral cortex polypeptide complex in calves. The mechanism of cortexin action is not understood well. Two cortexin…”
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The effect of short peptides on the growth and yield of soybeans by Aseeva, T. A., Khavinson, V. Kh, Mironova, E. S., Ryzhak, G. A., Selezneva, N. A., Fedorova, T. N.

“…Aim. Study of the effect of short di‐ and tetrapeptides (AB‐0, AE‐0) on the growth, development and productivity of Batya soybean varieties. Material and…”
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Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA by Fedoreyeva, L. I., Kireev, I. I., Khavinson, V. Kh, Vanyushin, B. F.

“…Marked fluorescence in cytoplasm, nucleus, and nucleolus was observed in HeLa cells after incubation with each of several fluorescein isothiocyanate-labeled…”
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Tripeptides Restore the Number of Neuronal Spines under Conditions of In Vitro Modeled Alzheimer’s Disease by Kraskovskaya, N. A., Kukanova, E. O., Lin’kova, N. S., Popugaeva, E. A., Khavinson, V. Kh

“…In primary culture of mouse hippocampal neurons, peptide EDR (200 ng/ml) under conditions of amyloid synaptotoxicity (a model of Alzheimer’s disease) increased…”
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Short Peptides Regulate Gene Expression by Khavinson, V. Kh, Lin’kova, N. S., Tarnovskaya, S. I.

“…Short peptides constitute the system of signal molecules regulating the functions of the organism at the molecular, genetic, subcellular, cellular, and tissue…”
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Molecular mechanism of interaction between oligopeptides and double-stranded DNA by Khavinson, V Kh, Solovyov, A Yu, Shataeva, L K

“…Formation of Ala-Glu-Asp-Gly peptide complex with duplex DNA [poly(dA-dT):poly(dA-dT)] at neutral pH and ambient temperature was studied experimentally…”
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A new stage of development of gerontology and geriatrics in Russia: problems of creation of a geriatric care system. Part 1. Relevance, regulatory infrastructure by Anisimov, V N, Serpov, V Yu, Finagentov, A V, Khavinson, V Kh

“…This article is a 1st part of the analytical review, focused on a new step in development of geriatrics in Russia. Creation of state system geriatric care as…”
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Peptides (Epigenetic Regulators) in the Structure of Rodents with a Long and Short Lifespan by Khavinson, V. Kh, Kormilets, D. Yu, Mar’yanovich, A. T.

“…We have discovered motives of short-chain epigenetically active peptides in some proteins of long-lived African mole rat Heterocephalus glaber. These…”
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Correction to: Tripeptides Restore the Number of Neuronal Spines under Conditions of In Vitro Modeled Alzheimer’s Disease by Kraskovskaya, N. A., Kukanova, E. O., Lin’kova, N. S., Popugaeva, E. A., Khavinson, V. Kh

“…On the page 553 Acknowledgements should be as follows: The study was supported by the Russian Science Foundation (grant 14-25-00024-P)…”
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