Search Results - "Khattree, Nidhi"
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Membrane curvature generation by a C-terminal amphipathic helix in peripherin-2/rds, a tetraspanin required for photoreceptor sensory cilium morphogenesis
Published in Journal of cell science (15-10-2013)“…Vertebrate vision requires photon absorption by photoreceptor outer segments (OSs), structurally elaborate membranous organelles derived from non-motile…”
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Journal Article -
2
Protective gene expression changes elicited by an inherited defect in photoreceptor structure
Published in PloS one (20-02-2012)“…Inherited defects in retinal photoreceptor structure impair visual transduction, disrupt relationship with the retinal pigment epithelium (RPE), and compromise…”
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Journal Article -
3
An Intramembrane Glutamic Acid Governs Peripherin/rds Function for Photoreceptor Disk Morphogenesis
Published in Investigative ophthalmology & visual science (01-07-2007)“…Peripherin/rds (P/rds), the product of the retinal degeneration slow (rds) gene, is a tetraspanin protein that plays a pivotal role for photoreceptor outer…”
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4
Regulation of tumor suppressor proteins, p53 and retinoblastoma, by estrogen and antiestrogens in breast cancer cells
Published in Oncogene (21-08-1997)“…We have utilized the estrogen receptor (ER)-positive human breast carcinoma cell line, T47D, to determine the role of ER in regulating cell proliferation, the…”
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5
Uncoupling of Photoreceptor Peripherin/rds Fusogenic Activity from Biosynthesis, Subunit Assembly, and Targeting
Published in The Journal of biological chemistry (17-09-2004)“…Inherited defects in the RDS gene cause a multiplicity of progressive retinal diseases in humans. The gene product, peripherin/rds (P/rds), is a member of the…”
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Journal Article -
6
Hormonal Regulation of the p53 Tumor Suppressor Protein in T47D Human Breast Carcinoma Cell Line ()
Published in The Journal of biological chemistry (01-12-1995)“…Under normal culturing conditions, the T47D human breast cancer cell line expresses progesterone receptor constitutively and is responsive to estrogen. Because…”
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Folding and Subunit Assembly of Photoreceptor Peripherin/rds Is Mediated by Determinants within the Extracellular/Intradiskal EC2 Domain
Published in The Journal of biological chemistry (16-11-2001)“…Peripherin/rds is an integral membrane protein required for the elaboration of rod and cone photoreceptor outer segments in the vertebrate retina; it causes a…”
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8
Estrogen-dependent and independent activation of the P1 promoter of the p53 gene in transiently transfected breast cancer cells
Published in Oncogene (28-01-1999)Get full text
Journal Article -
9
In situ visualization of protein interactions in sensory neurons: glutamic acid-rich proteins (GARPs) play differential roles for photoreceptor outer segment scaffolding
Published in The Journal of neuroscience (03-08-2011)“…Vertebrate photoreceptors initiate vision via a G-protein-mediated signaling cascade organized within a specialized cilium, the outer segment (OS). The…”
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10
Folding and subunit assembly of photoreceptor peripherin/rds is mediated by determinants within the extracellular/intradiskal EC2 domain: implications for heterogeneous molecular pathologies
Published in The Journal of biological chemistry (16-11-2001)“…Peripherin/rds is an integral membrane protein required for the elaboration of rod and cone photoreceptor outer segments in the vertebrate retina; it causes a…”
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Journal Article -
11
Uncoupling of photoreceptor peripherin/rds fusogenic activity from biosynthesis, subunit assembly, and targeting: a potential mechanism for pathogenic effects
Published in The Journal of biological chemistry (17-09-2004)“…Inherited defects in the RDS gene cause a multiplicity of progressive retinal diseases in humans. The gene product, peripherin/rds (P/rds), is a member of the…”
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Journal Article -
12
Hormonal regulation of tumor suppressor proteins in breast cancer cells
Published in Journal of steroid biochemistry and molecular biology (01-01-2001)“…This laboratory is studying hormonal regulation of tumor suppressor proteins, p53 and retinoblastoma (pRB). Estrogen receptor and progesterone receptor…”
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Journal Article Conference Proceeding -
13
Differential regulation of retinoblastoma protein by hormonal and antihormonal agents in T47D breast cancer cells
Published in The Journal of steroid biochemistry and molecular biology (01-05-2001)“…Phosphorylation of the tumor suppressor protein, retinoblastoma (pRb), regulates the progression of the cell cycle. Previous work from this laboratory had…”
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Journal Article -
14
Agonist and antagonist-induced qualitative and quantitative alterations of progesterone receptor from breast cancer cells
Published in Molecular and cellular biochemistry (01-09-1999)“…T47D cells, cultured in medium containing serum stripped of endogenous steroids, proliferate in response to treatment with the progesterone receptor (PR)…”
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